Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…In this study, we utilised structure-based virtual screening (SBVS) from NCI library to discover novel DYRK1A inhibitors. …”

Data Sheet 1_Synergistic remediation of continuous cropping obstacles in facility agriculture: insights from the Stropharia rugosoannulata-Ornamental Sunflower Rotation System.docx by Jia Lu (181094)

“…The SR-OS2 system significantly enhanced soil properties by increasing pH (+0.57 units), decreasing electrical conductivity (−37.56%), and boosting available phosphorus (+84.2%), while also shifting microbial communities toward bacterial dominance with a 37.4% increase in bacterial Chao1 diversity and a 39.1% decrease in fungal diversity, alongside strengthened bacterial connectivity (+42%) and reduced fungal modularity in co-occurrence networks. …”

Actual Vs predicted revenue. by Guibing You (21728593)

“…To address this challenge, we propose F-TransR, a Transformer-based multimodal revenue prediction model. …”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Genetic evidence linking gastroesophageal reflux disease to chronic kidney disease and kidney failure: a two-step Mendelian randomization study by Fanghong Zheng (8931326)

“…Interventions with these factors could significantly decrease the burden of CKD attributable to GERD.…”

None - by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”

Dust particle size distribution. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Model parameter setting. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Grid division diagram. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Unpowered dust removal device stereogram. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Physical model. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Dust particle flow trace diagram. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Discrete phase parameter setting. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Dust deposition, escape data table. by Yuxuan Liu (349237)

“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”

Image_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.JPEG by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Table_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.DOCX by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome by Geoffrey S. Kelly (21537766)

“…After adjustments, droperidol use was associated with a reduced length of stay (mean ratio 0.76; 95% CI: 0.62 0.94; <i>P</i> = 0.01), decreased total medication administration (OR 0.34; 95% CI: 0.20–0.58; <i>P <</i>0.001) and decreased usage of opioids (OR 0.16; 95% CI: 0.07–0.39; <i>P <</i>0.001). …”

Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf by figshare admin frontiersin (4545187)

“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”

Image 1_SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.tif by Junchen Pan (19417598)

“…RT-PCR and Western blot analyses were used to investigate the relevant molecular mechanisms.</p>Results<p>We show that SQLE is significantly overexpressed in pancreatic cancer, and abrogation of SQLE results in a significant increase in squalene accumulation within tumor cells. …”

Data Sheet 1_Shifts in soil microbial and nematode communities over progression of pine wilt disease occurring in Pinus koraiensis stands.pdf by Siyu Tian (9874001)

“…Consequently, we observed a lower inter-kingdom network complexity in the soil community of the pines following the PWD, in which the bacterial networks decreased but fungal networks increased in complexity. …”