The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model by Zichen Huang (6587885)

“…The IRF-1–associated gene–based machine learning model provides a robust, noninvasive diagnostic tool.</p>…”

Statistical analysis of the AUC measurement. by Esra Ayan (21156015)

“…The mean AUC decreased in both samples.</p> <p>(TIF)</p>…”

Isolation and characterization of the <i>clr4–1</i> mutant strain. by Ziyue Liu (381532)

“…Data are presented as mean ± SD from three independent experiments. Statistical significance was determined using a one-way ANOVA followed by Dunnett’s multiple comparison test, with WT as the reference sample (*<i>p</i> < 0.05 and **<i>p</i> < 0.01; N.S.: not significant).…”

Data Sheet 1_Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.pdf by Louis Schreel (22385035)

“…</p>Results<p>Beneficial cardiometabolic effects included a decrease in mean Lp(a) of 6.6 mg/dl (−21%), a reduction in mean triglyceride of 40.6 mg/dl (−30%), a reduction in mean apoB of 0.14 g/L (−10,5%) and an increase in mean HDL-C of 3 mg/dL (+5%), a reduction in mean hsCRP of 0.94 mg/L (−45%), a reduction in mean TNF-α of 1.31 pg/ml (−7%), a reduction in mean MDA-LDL of 36.77 U/L (−38%), a reduction in mean nitrotyrosine of 225 nmol/L (−28%), a mean weight reduction of 4 kg (−4,6%), a mean visceral fat reduction of 0.69% (−10%) and a mean fat mass reduction of 3.7 kg (−12%). …”

The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis by Guowen Zhao (19775328)

“…<p>Gastrointestinal bleeding is an important gastrointestinal complication among peritoneal dialysis patients and correlated with a higher risk of mortality. Increased uric acid levels are a significant complication for peritoneal dialysis patients and have been associated with an increased risk of hemorrhagic stroke. …”

Fig S1. by Leonardo Santos (477304)

“…Black arrows indicate the formation of heteroduplexes, which are absent in the controls of uninduced and untransfected cells, as well as in induced but untransfected cells (Ctrl and Ctrl2, respectively). A noticeable decrease in amplicon yield suggests significant modifications following Cas9 cleavage and DNA repair processes. …”

Efficacy and safety of anticoagulation in asymptomatic cirrhotic patients with portal vein thrombosis: a systematic review and meta-analysis by Qingping Wu (789611)

“…Compared to no intervention, anticoagulation significantly increased the PVT recanalization rate (OR = 3.89, <i>p</i> < .001) and decreased the PVT progression rate (OR = 0.28, <i>p</i> < .001) as well as overall mortality (OR = 0.66, <i>p</i> = .008). …”

RBM39 is methylated by PRMT6 at arginine 92. by Tongjia Zhang (16496661)

Table 1_The effectiveness of exercise interventions in the improvement of sleep in older adult people: a meta-analysis.docx by Di Geng (1681915)

“…Background<p>Sleep problems are prevalent among the older adult population, with a significant impact on their health and overall well-being. …”

Data Sheet 1_Factors affecting posaconazole plasma concentrations: a meta-analysis and systematic review.docx by Ruochen Qu (16946790)

“…High-fat meals, age, and sex did not have a significant impact on posaconazole oral suspension (POS) concentrations. …”

Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx by Yi-Ting Sun (4691629)

“…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …”

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…VMAT significantly improved the V₃₀ of PTV-brain-SIB (p<0.001), decreased HI (p=0.003), and increased CI (p<0.001). …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for α-diversity index were estimated using a random effects model. …”

<b>Fire Severity Alters Soil Microbial Diversity and Community Stability in a Subtropical Forest Ecosystem</b> by Xuezhao (21803957)

“…Moreover, low-severity fires increased the functional taxa associated with chemoheterotrophic and aerobic chemoheterotrophic bacteria, whereas the ectomycorrhizal fungi was significantly reduced in fired plots. Network analysis indicated that the complexity and connectivity of microbial networks gradually decreased with increasing fire severity.…”

Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc by Hua Chai (280388)

“…<p>Carbon (C) fluxes in semiarid grasslands subject to precipitation variability play a critical role in the terrestrial C cycle. However, how ecosystem C fluxes respond to variability in precipitation (both decreases and increases precipitation along a gradient) remains unclear. …”

Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx by Jianzu Wu (13935369)

“…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …”

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

The Patient Global Impression of Change as a complementary tool to account for neurobehavioral and mental health symptom improvement for patients with concussion by Rosemay A. Remigio-Baker (7864583)

“…</p> <p>Higher PGIC scores were related to a higher prevalence of clinically-relevant <i>decrease</i> in NSI, PCL-5 or PHQ-8 scores. …”

Supplementary Material for: High-sensitivity Troponin I Measurement in a Large Contemporary Cohort: Implications for Clinical Care by Esau D. (20563829)

“…Male sex, higher HDL-C, higher Hgb A1c, decreasing eGFR, and increasing systolic blood pressure were significant predictors of increased hsTnI. …”