Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... by Yuanhang Rong (19207540)

“…Risk of bias was evaluated following the Systematic Review Center for Laboratory Animal Experiments. The mean difference (MD) or standard mean difference (SMD) with 95% confidence intervals (CIs) were used to evaluate the effect of Tan ⅡA on cognitive function, neuropathology, neuroinflammation, oxidative stress, apoptosis, and neural/synaptic plasticity, with P < 0.05 considered a significant difference. …”

Upper-crust thermal evolution of the Patagonian Precordillera basement (Argentina): insights from fission track, (U-Th)/He thermochronology and geodynamic significance by Paulo Marcos (7459064)

“…This first stage might have resulted from coupled tectonothermal processes consisting of extensional faulting and high-temperature gradient. Subsequently, a relatively fast temperature decrease (2.75–5°C/My) for the late Early Cretaceous to Paleocene is likely related to a compressive stage associated with the growth of the early Andean Orogen. …”

Images and quantitative results from bone fragment evaluation. by Marsel Ganeyev (21453399)

Histologic evaluation of the osteotomy site. by Marsel Ganeyev (21453399)

Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Table 1_Gamma knife radiosurgery for cerebral cavernous malformations: biologically effective dose predicts therapeutic outcomes.docx by Xiaoman Shi (12587770)

“…During follow-up, 13 patients (10.6%) experienced hemorrhage and AHR decreased from 13.6 to 4.3% per 100 lesion-years (IRR = 0.314; p < 0.001). …”

Evolutionary relationships between tooth size and jaw protrusion. by Nick Peoples (21593888)

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Impact of p53 T253I on DNA damage responsive mRNA expression. by Nathaniel C. Holcomb (22793595)

Impact of p53 T253I on expression of DNA damage responsive proteins. by Nathaniel C. Holcomb (22793595)

Subcellular fractionation of HEK293 p53 wt and mutant proteins. by Nathaniel C. Holcomb (22793595)

Flow chart of sediment P fractionation procedure. by Jiayu Hu (673291)

“…The NH₄Cl-Po and NaHCO₃-Po concentrations in sediments showed the greatest decrease (accounting for 97.6% of total decrease) during the experiment. …”

The raw data of the paper with the title of " The Protective Effect of Schisandrin C against Methicillin-Resistant Staphylococcus aureus - Induced Otitis Media " by Weifang Sun (22459180)

“…<p dir="ltr"><a href="" target="_blank">Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a significant pathogen in </a><a href="" target="_blank">otitis media</a> (OM), including acute otitis media (AOM) and chronic suppurative otitis media (CSOM), presenting considerable therapeutic challenges due to its biofilm formation, host immune evasion and promotion of persistent inflammation. …”

Table 3_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.xlsx by Aihua Guo (13267712)

“…</p>Conclusions<p>This study clarifies NOTCH1’s role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.…”

Table 1_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx by Aihua Guo (13267712)

“…</p>Conclusions<p>This study clarifies NOTCH1’s role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.…”

Table 2_Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity.docx by Aihua Guo (13267712)

“…</p>Conclusions<p>This study clarifies NOTCH1’s role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.…”

Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... by Liang Wu (131111)

“…Gut microbiota analysis revealed a significant increase in the abundance of Turicibacter, while a reduction of Ruminococcus. …”