Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx by Hailan Yan (18174379)

“…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …”

Table 4_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... by Ulrike Gimsa (9730208)

“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”

<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... by Kangning Yan (22751487)

“…Furthermore, aboveground Si content decreased significantly from leaves (10.54–21.45 g kg–1) to branches (3.81–5.61 g kg–1) and culms (1.07–1.98 g kg–1). …”

Table 3_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... by Ulrike Gimsa (9730208)

“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”

Data Sheet 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.pdf by Rui Jiang (264894)

“…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …”

Table 5_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... by Ulrike Gimsa (9730208)

“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”

Data Sheet 1_Effectiveness of community-based management models in chronic obstructive pulmonary disease: a systematic review and meta-analysis.docx by Miao Zhan (2625718)

“…The community-based management models demonstrated significant improvements in the 6-min walk test (mean difference [MD] = 39.73; 95% confidence interval [CI, 30.15, 49.32]; p < 0.00001) and lung function parameters (forced expiratory volume in the first second/forced vital capacity [FEV1/FVC]: MD = 6.17; 95% CI [4.54, 7.79], p < 0.00001; FEV1% predicted: MD = 4.91, 95% CI [3.96, 5.85], p < 0.00001). …”

Toxic activity of AS56 on the larval feeding behavior of <i>S. exigua.</i> by Niayesh Shahmohammadi (21262234)

“…Different letters above standard error bars or asterisks denote significant differences among means at Type I error = 0.05 (LSD test). …”

Data Sheet 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.xlsx by Xiong-Gang Yang (22645370)

“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”

Image 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.jpeg by Xiong-Gang Yang (22645370)

“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”

Table 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.docx by Xiong-Gang Yang (22645370)

“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”

Additive Benefits of Control-IQ+ AID to GLP-1 Receptor Agonist Use in Adults with Type 2 Diabetes by Timothy E. Graham (22352054)

“…</p><p dir="ltr">Results: Among GLP1-ra users, mean HbA1c decreased by 0.8% from a baseline of 8.0±1.2% with AID, which represented a mean improvement of -0.5% (95% CI -0.8 to -0.3, p<0.001) compared with the CGM group. …”

Supplementary Material for: Additive inhibition of HERG channels expressed in Xenopus oocytes by antipsychotic drugs and citrus juice flavonoid naringenin by Yang K.-H.S. (18331101)

“…Methods: In the present study, we evaluated the effect of combining naringenin with antipsychotics on the function of HERG channels expressed in Xenopus oocytes. …”

Method for establishing the multipath adaptive mitigation model considering deformation displacement of monitoring stations by Guo Zihuai (20442074)

“…The comparison between MAMM and the Multipath Hemispherical Model (MHM) indicates that, in the simulated displacement experiments, MHM’s effectiveness in mitigating multipath errors significantly decreases as the actual displacement distance increases, whereas MAMM consistently maintains an improvement rate in positioning precision of over 100%, markedly surpassing that of MHM. …”

S1 File - by Qian Wang (32718)

“…Prior cancer history had little impact on DSS; however, the presence of prior solid cancer history, latency period of 10+ years, and prior administration of radiotherapy or chemotherapy significantly decreased OS. Prior cancer history had no effect on DSS, but survival compromised OS under specific circumstances.…”

Table 1_The impact of digital economy on the supply chain resilience of cross-border healthcare e-commerce.xlsx by Jianyu Liu (313522)

“…The results indicate that the digital economy significantly enhance supply chain resilience, with reduced reliance on foreign trade, increased export technology complexity, and decreased export concentration being key pathways for this improvement. …”

Data Sheet 1_China’s readiness for transitioning to a low-carbon economy: mitigant and catalyst factors for a geopolitical conflict.zip by Yan Chen (4308)

“…This study examines the relationship between Low-Carbon Economic Development (LCED) and Geopolitical Risk (GPR) in China by focusing on the challenges and opportunities they present. We use a qualitative analysis to identify that rising GPR, exacerbated by market instability, resource allocation conflicts, and trade disputes, significantly hinders LCED progress. …”

Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg by Na Wang (193263)

“…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

The effect of cognitive behavioral therapy-based psychoeducation on substance abuse proclivity in adolescent smokers by Behiye Dilmen Bayar (19133390)

“…The difference between the posttest SAPS total mean scores of the control and experimental groups was statistically significant.…”