Supplementary Material for: Diverse Obesity Trajectories in a Family including Identical Twins with a Pathogenic MC4R Variant by figshare admin karger (2628495)

“…Twin 2 had a sedentary lifestyle and epilepsy and had a peak BMI of 30.1 kg/m2; she responded well to naltrexone-bupropion and BMI decreased to 26 kg/m2. Conclusion: The manifestation of obesity, even in cases of monogenic obesity, can vary significantly due to the influence of environmental and lifestyle factors.…”

Table1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Table 1_The prevalence and correlates of falls in adults with attention-deficit/hyperactivity disorder: cross-sectional study.docx by Maraheb M. Alkhalidi (22389535)

“…</p>Results<p>Forty-five adults (35 women; mean age = 28.4 ± 6.3 years) were enrolled in the study. …”

Data Sheet 1_Increased epicardial tissue and reduced TAPSE and MAPSE scores in borderline personality disorders. Early indicators for cardiovascular risk?.pdf by Charlotte F. M. Schaefer (21466880)

“…Additionally, significant decreases in right (TAPSE) and left (MAPSE) ventricular function, albeit within the normal range, were measured in BPD patients. …”

DataSheet1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.docx by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Table2_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway. by Jingtong Xiong (22272139)

“…(d) CCK-8 OD values were decreased after Nrf2/HO-1 inhibition, with lower values observed in the OGD/R+CLIC1 silencing+Nrf2/HO-1 inhibition group than the OGD/R+CLIC1 silencing group. …”

Table4_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Fig 3 - by Nehal Shawky Nagy (17721213)

“…Values are expressed as mean ± SEM; n = 3 rats for each group. Different superscripts on the columns are significantly different at p≤0.05.…”

Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx by Yihan Sun (3432287)

“…No significant increase in adverse drug events (ADEs) was observed (RR = 1.32, 95% CI 0.58–2.96). …”

Sex-specific brain volume changes in ECM. by Alicia Comino Garcia Muñoz (22075399)

“…The color code used in the brain views inserted in the graphs indicates whether the brain structure represented is increasing (green), decreasing (red) or remaining unchanged (blue). Data are presented as mean ± SD. 10 males (purple symbols), 10 females (yellow symbols). …”

S2 Data - by Chelsea A. Simpson (9579303)

“…</sub> For panels C and E, error bars show the mean and standard deviation of at least 3 biological replicates. …”

Table3_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Side effect. by My Tra Thi Nguyen (22120541)

“…UAS7 average scores decreased from a baseline mean of 28.9 to 2.9, indicating substantial reduction in disease activity. …”

The quality metrics of 4C-seq data. by Tingting Jiang (169999)

“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”

<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor by Mo-Fei Li (21624535)

“…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …”

Data Sheet 1_Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway.docx by Xinxin Li (281237)

“…Although recent advancements have highlighted the pivotal role of ribosomes in the progression of B-ALL, the specific function of ribosomal protein L9 (RPL9), a key component of ribosomal structural protein, still unclear. In this study, we observed a significant upregulation of RPL9 in human B-ALL cells compared to normal B cells, suggesting RPL9’s potential key role in B-ALL progression. …”

Renal function and risk of dementia: a Mendelian randomization study by Haowen Huang (1430386)

“…At the stratum of genetic susceptibility, we tested the causal relationship between variations index in renal function and the occurrence of dementia. …”

Image 1_Yacon root is a functional food beneficial for human health: a meta-analysis of clinical trials.pdf by Ling-Hui Pan (9341084)

“…The pooled results showed that YR significantly reduced BMI [SMD = −0.81, 95%CI (−1.54, −0.08)], decreased stool pH [SMD = −1.12, 95%CI (−1.61, −0.62)], softened stools [SMD = 0.94, 95%CI (0.08, 1.80)], facilitated defecation [SMD = 4.03, 95% CI (0.54, 7.52)], improved fiber consumption patterns [SMD = 0.58, 95%CI (0.18, −0.99)]. …”

Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx by Mallory A. Perry-Eaddy (20842868)

“…</p>Methods<p>We conducted a post hoc secondary analysis of the MitoPSe clinical study, including N = 119 critically ill children who survived sepsis. …”