Photomicrographs of H&E-stained cerebellum sections from control and different pregnant mothers: control (A & B) and BM (C & D) groups, showing normal histological structure of the... حسب Amoura M. Abou-El-Naga (21001524)

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction حسب Zhihui Liu (95891)

"…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …"

Immuno-infiltration analysis. حسب Wan-Jing Zhen (20427813)

S1 File - حسب Ruiming Xiao (6389546)

"…In this study, metabolomics analysis revealed a significant increase in the main contents of lactic acid and propionic acid in FCM, while most glycosides and their derivatives decreased after three days of microbial fermentation. …"

Primers used for PCR and qRTPCR. حسب Huan W. Yang (19746645)

"…There were no significant changes in NF-κB signalling between vaccine and Dkp23 infection in PK-15 cells, except for moderate levels of differences in NF-κB target genes expression which might be a reflection of differences in intracellular bacterial load. …"

Western blots used for Fig 4C. حسب Huan W. Yang (19746645)

"…There were no significant changes in NF-κB signalling between vaccine and Dkp23 infection in PK-15 cells, except for moderate levels of differences in NF-κB target genes expression which might be a reflection of differences in intracellular bacterial load. …"

GSVA results. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

Differential expressed genes. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

S1 Raw image - حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

Venn plot. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

Key module genes. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

Univariate and multivariate Cox analysis. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

S3 Fig - حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

KEGG enrichment analysis. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

GSEA results. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

GO enrichment analysis. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"

Magnification x2 of Fig 1B. حسب Huan W. Yang (19746645)

"…There were no significant changes in NF-κB signalling between vaccine and Dkp23 infection in PK-15 cells, except for moderate levels of differences in NF-κB target genes expression which might be a reflection of differences in intracellular bacterial load. …"

GSEA and GSVA enrichment analysis. حسب Wan-Jing Zhen (20427813)

Construction of diagnostic model of ERSRGs. حسب Wan-Jing Zhen (20427813)

Flow chart of the study process. حسب Wan-Jing Zhen (20427813)

"…</p><p>Conclusions</p><p>This study elucidated the interplay between metabolism and the immune microenvironment in SIC, providing fresh perspectives on the investigation of potential SIC pathogenesis. PDHB emerged as a significant biomarker of SIC, with implications on its progression through the regulation of ERS and metabolism.…"