Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys by Ornella Binazon (20718978)

“…<p>Efgartigimod is a human IgG₁ antibody F_c fragment that reduces IgG levels through neonatal F_c receptor blockade. …”

CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells. by Jovana Deretic (13113617)

“…Ciliary vesicle ectocytosis or fragments were categorized based on the size of the released EVs, vesicle < 500 nm and fragment > 500 nm, and plotted as a bar plot. (<i>p</i> values of Welch’s <i>t</i> test, **<i>p</i> = 0.0074, ***<i>p</i> = 0.0007, ns = not significant). …”

Image 2_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…The CSA of the right PCUN showed a significant positive correlation with MMSE score in LPD patients. …”

Image 1_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…The CSA of the right PCUN showed a significant positive correlation with MMSE score in LPD patients. …”

Image 3_Changes of brain structure and structural covariance networks in Parkinson’s disease with different sides of onset.tif by Tianqi Xu (9574329)

“…The CSA of the right PCUN showed a significant positive correlation with MMSE score in LPD patients. …”

Table 1_Redox status of biomarkers in serum of dogs with hypothyroidism and its treatment with levothyroxine sodium.docx by Ling Zhu (56356)

“…Dogs with hypothyroidism had decreased levels of serum T4 and fT4 and increased levels of serum TSH. …”

Table 2_Redox status of biomarkers in serum of dogs with hypothyroidism and its treatment with levothyroxine sodium.docx by Ling Zhu (56356)

“…Dogs with hypothyroidism had decreased levels of serum T4 and fT4 and increased levels of serum TSH. …”

Robust chain-length specific reductions in some intermediate chain and long chain PE phospholipids in peroxisomal mutant brain. by Michael F. Wangler (21526595)

“…<p><b>A.</b> Levels in mol% of PE 33:3 in <i>pex2</i> and <i>pex16</i> mutant brains show significant decreases in <i>pex</i> mutant brains. …”

Table 1_How social integration affects the income of relocated households: evidence from China.xlsx by Chuangxin Zhao (20561618)

“…The results show that: social integration has a significant positive effect on the household income level of relocated farmers, and the effect of social integration on household income decreases with the increase of income level. …”

Structural analysis of wild type and mutated variants of CXCR4. by Bonoshree Sarkar (20469331)

“…The changes in H-bond in the 3D structure of the CXCR4 protein likely have a significant impact on the structure functions of the protein.…”

Data Sheet 1_Global burden of inflammatory bowel disease in the elderly: trends from 1990 to 2021 and projections to 2051.docx by Ying Liu (18461)

“…Estimated annual percentage changes (EAPCs) were computed to quantify temporal trends. A Bayesian Age-Period-Cohort model was employed to project future trends.…”

Care quality. by Youssef Hbid (18803761)

“…Stroke multidisciplinary access increased during the first lockdown but decreased in subsequent periods. Access to thrombectomy sequentially increased across time periods; by 40% during first lockdown (adjusted Odd-Ratio: 1.4; 95% CI:1.24–1.58), second lockdown (aOR: 1.77; 1.66–1.92), and 2-folds post-lockdown (aOR: 2.03; 1.92–2.15). …”

Outcomes at discharge. by Youssef Hbid (18803761)

“…Stroke multidisciplinary access increased during the first lockdown but decreased in subsequent periods. Access to thrombectomy sequentially increased across time periods; by 40% during first lockdown (adjusted Odd-Ratio: 1.4; 95% CI:1.24–1.58), second lockdown (aOR: 1.77; 1.66–1.92), and 2-folds post-lockdown (aOR: 2.03; 1.92–2.15). …”

Patient characteristics. by Youssef Hbid (18803761)

“…Stroke multidisciplinary access increased during the first lockdown but decreased in subsequent periods. Access to thrombectomy sequentially increased across time periods; by 40% during first lockdown (adjusted Odd-Ratio: 1.4; 95% CI:1.24–1.58), second lockdown (aOR: 1.77; 1.66–1.92), and 2-folds post-lockdown (aOR: 2.03; 1.92–2.15). …”

Data Sheet 1_Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021.doc by Ming Wang (172316)

“…Additionally, gender plays a significant role in the distribution of this burden, with males experiencing a higher burden than females. …”

Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx by Qingguo Liu (9620123)

“…</p>Conclusions<p>Despite a decline in ASDR, the absolute burden of stroke attributable to metabolic risks among young adults has increased globally, with significant regional and national disparities. …”

Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …”

Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Image 4_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Data Sheet 1_Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass.docx by Ruoyu Gou (11835929)

“…Background<p>Chronic Obstructive Pulmonary Disease (COPD) is a major global health concern, with lifestyle factors playing a crucial role in its prevention. …”