Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf حسب Juanjuan Zhang (432819)

"…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …"

Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx حسب Xinxin Li (281237)

"…Furthermore, we observed that enforced upregulation of SMAD4 resulted in enhanced cytotoxicity of NK cells towards CRC cells. …"

Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... حسب Huihui Zhu (4483621)

"…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …"

Table 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.xlsx حسب Ye Li (290115)

"…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …"

Image 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.tif حسب Weichao He (16832265)

"…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …"

Mass spectrometry of Pparα-En4 pulldown proteins. حسب Tingting Jiang (169999)

"…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"

Table 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.docx حسب Kaisong Huang (5412626)

"…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …"

Data Sheet 1_Soil fungal community and co-occurrence network patterns at different successional stages of black locust coppice stands.docx حسب Huimei Tian (499744)

"…Significant changes in the relative abundance of certain fungal guilds were observed by both stand conversion and seasonal variation (p < 0.05). …"

Table 1_Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic revie... حسب Zhenzhen Zhao (782550)

"…A significant association was found between decreased serum BDNF concentrations and cognitive impairment in PD (SMD = −1.035; 95% CI [−1.340, −0.730]; P < 0.001). …"

Caffeine induces proteome-wide changes in a Rob-dependent manner. حسب Christoph Binsfeld (21763112)

"…The double-sided Fisher’s exact test p-value for enrichment of OMPs among significantly decreased proteins is shown. (D) Comparison of proteome changes between wild type and Δ<i>rob</i> upon caffeine treatment. …"

Table_1_Refugees’ integration and emotional distress over the course of 9 months.pdf حسب Flurina Potter (16537140)

"…</p>Results<p>Overall, emotional distress decreased, and integration increased over time. In particular, the sub-dimensions of social, economic, and linguistic integration increased significantly over time<sub>.…"

Table_1_Refugees’ integration and emotional distress over the course of 9 months.pdf حسب Flurina Potter (16537140)

"…</p>Results<p>Overall, emotional distress decreased, and integration increased over time. In particular, the sub-dimensions of social, economic, and linguistic integration increased significantly over time<sub>.…"

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... حسب Yuhua Jiang (10300159)

"…PSCK9 inhibitors and potent statins significantly reduced LDL-C levels from baseline vs. placebo regardless of background therapy. …"

Table 1_Efficacy of valgus osteotomy in treating nonunion of femoral neck fractures post-internal fixation.docx حسب Haohao Xu (8909687)

"…The mean neck-shaft angle increased from 118.91° to 139.26° (p < 0.001), whereas the Pauwels angle decreased from 62.07° to 46.91° (p < 0.001). …"

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx حسب Mingming Xie (20963636)

"…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …"

Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip حسب Peixi Zhao (620068)

"…</p>Methods<p>Using data from the GBD 2021 data, we conducted a secondary analysis. We assessed the prevalence, mortality, and disability-adjusted life years (DALYs) of MS across 204 countries/territories from 1990 to 2021, calculating age-standardized rates.…"

Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx حسب Peixi Zhao (620068)

"…</p>Methods<p>Using data from the GBD 2021 data, we conducted a secondary analysis. We assessed the prevalence, mortality, and disability-adjusted life years (DALYs) of MS across 204 countries/territories from 1990 to 2021, calculating age-standardized rates.…"

Data Sheet 1_Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner.docx حسب Moriah R. Arnold (20908868)

"…</p>Methods<p>Our study created and characterized Snca knockout in the spontaneously developing melanoma TG3 mouse line, TG3+/+Snca-/-. </p>Results<p>We show that αSyn loss-of-function significantly delays melanoma onset and slows tumor growth in vivo in males. …"