Data Sheet 1_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.pdf by Alexandra Prodea (22617710)

“…The toxicity assessment revealed that triterpenes have in general, insignificant or absent toxicity, with only a small number of studies reporting serious side effects such as leukopenia, hepatotoxicity and mortality at specific doses that were reversed in some cases by the use of carriers, which hold the potential to enhance the therapeutic effect of triterpenes while reducing their systemic toxicity.</p>Conclusion<p>We concluded that the current in vivo evidence does not support the clinical translation of triterpenes for the treatment of breast cancer due to methodological and clinical heterogeneity as well as the lack of toxicity data in a significant number of studies. …”

Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf by Dilara Yılmaz (19710658)

“…While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse models such as PolgA^D257A/D257A (PolgA) has not been completely explored. We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …”

Water bridges by Raman Jangra (19231711)

“…To delineate the structural role of water molecules in shaping the interactions between RNA and proteins, we comprehensively analyzed a dataset of 329 high-resolution crystal structures of RNA–protein complexes to identify water-mediated hydrogen-bonded contacts at the RNA–protein interface. …”

Data Sheet 1_Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood.pdf by Hanane Omichessan (4991552)

“…Serum levels of PFOS and PFOA were measured by liquid chromatography coupled to tandem mass spectrometry.</p>Results<p>We found 64 CpG sites with significant hypomethylation or hypermethylation associated with increased levels of PFOA or PFOS (p-value_Bonferroni < 0.05). …”

Spatial variation and clgassification of anthropogenic soils formed by long-term “<i>Dorotsuke”</i> soil-dressing in Andosols of the Omiya Upland along the Arakawa River, Japan by Shokichi Wakabayashi (3872428)

“…The two anthropogenic horizons exceeded 50 cm in thickness with different soil textures, while one of the other two showed significant mixing with Andosol. The profiles exhibited a vertical attenuation of andic characteristics, including increased bulk density, decreased short-range-order mineral content, and reduced phosphate retention, from the buried Andosol up to the topsoil. …”

Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo... by William L. Tong (22238845)

“…<p>See the text for more details of the task in the continuous setting. B: ADP significantly outperforms INC when the task is difficult (low <i>ε</i>). …”

Data Sheet 1_Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database.docx by Peiyang Cao (10808613)

“…Notably, strong ADE signals were detected for decreased urine osmolality [n = 5, ROR 149.74, PRR 149.7, IC (Information Component) 7.13, EBGM (Empirical Bayes Geometric Mean) 139.79], osmotic demyelination syndrome (n = 38, ROR 128.47, PRR 128.25, IC 6.92, EBGM 120.91), and pulmonary-related tumors such as bronchial metastatic carcinoma, bronchial carcinoma, metastatic small cell lung carcinoma, and small cell lung carcinoma. …”

Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx by Xingxing Yin (7919447)

“…The distribution of older adult care institutions and the aging population shows a positive trend, with the matching degree constantly increasing. The mean deviation index (M) decreased from 0.015 in 2005 to 0.011 in 2020. …”

Table 1_Effects of singing on vascular health in older adults with coronary artery disease: a randomized, crossover trial.docx by Mehri Bagherimohamadipour (21189317)

“…</p>Results<p>Sixty-five subjects (mean age 67.7 ± 0.8 years, 40% female) completed the study. …”

TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts by Thuc Ly (12832686)

“…Using both a literature based, and an unbiased approach, we studied the molecular machinery involved in autophagosome trafficking in CAFs. …”

DataSheet1_IVIG response in pediatric acute-onset neuropsychiatric syndrome correlates with reduction in pro-inflammatory monocytes and neuropsychiatric measures.docx by Isaac Melamed (6291590)

“…</p>Results<p>All ten patients included in the study were male, White, with mean age 12.4 years (range 6–16). Statistically significant improvements following IVIG treatment were demonstrated in all psychometric assessments and parent questionnaires including CY-BOCS (obsessive compulsive scale), YGTSS (tic scale) and a parent PANS rating scale (for all scales p<0.001). …”

Table_3_Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data.XLSX by Yongyue Miao (19925808)

“…Background<p>Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. …”

Table_2_Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data.xlsx by Yongyue Miao (19925808)

“…Background<p>Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. …”

Data_Sheet_1_Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data.zip by Yongyue Miao (19925808)

“…Background<p>Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. …”

Table_1_Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011–2018 data.docx by Yongyue Miao (19925808)

“…Background<p>Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. …”

Thymoquinone loaded nanoemulgel in streptozotocin induced diabetic wound by Urati Anuradha (20306190)

“…</p> <p>In diabetic wound animal model nanoemulgel showed significant decreased levels of TNF-α, IL-6, MMP-9 and IL-1β. …”

Table 1_Has carbon finance been able to promote clean energy development? — a low-carbon technology innovation perspective.xlsx by Rui Cui (622759)

“…It is found that carbon finance significantly promotes clean energy development, but this contribution decreases with the intervention of low-carbon technology innovation. …”

Image 2_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb... by Jiayao Qu (11309880)

“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”

Image 1_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb... by Jiayao Qu (11309880)

“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”

Image 2_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... by Xinchi Shang (11982840)

“…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …”