بدائل البحث:
linear decrease » linear increase (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
linear decrease » linear increase (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
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3781
Source data for Fig 5.
منشور في 2025"…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …"
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3782
Source data for Fig 1.
منشور في 2025"…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …"
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3783
Flow cytometry gating strategy for MDSC.
منشور في 2025"…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …"
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3784
Source data for Fig 3.
منشور في 2025"…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …"
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3785
Source data for Fig 4.
منشور في 2025"…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …"
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3786
Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations
منشور في 2025"…Enzyme kinetics results suggest that the improvement in enzyme performance largely stems from the decrease in enzyme–substrate affinity along the substrate transfer pathway. …"
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3787
Participant characteristics by village.
منشور في 2025"…We hypothesized that farmers with greater market-based wealth and more farming experience would have higher odds of adaptation. …"
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3788
Description of the variables and data sources.
منشور في 2025"…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …"
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3789
Descriptive statistics of the variables.
منشور في 2025"…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …"
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3790
Eq 13.
منشور في 2025"…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …"
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3791
School learning model dispositions data.
منشور في 2025"…P-values<0.050 were considered significant. From 2019 to 2021, reported persistent feelings of sadness/hopelessness (2019 = 36.3%, 2021 = 41.3%), seriously considering suicide (17.0-18.7%), making suicide plan(s) (14.2-16.9%), and experiencing sexual dating violence in past 12 months (6.7-7.8%) increased significantly, while alcohol use (22.5-17.1%), binge drinking (8.5-6.2%), and marijuana use (20.2-14.3%) in past 30 days, ever prescription opioid misuse (16.0-13.2%), and gun-carrying (5.5-4.5%), physical fighting (22.3-17.3%), and any sexual violence (11.3-10.4%) in past 12 months decreased significantly. …"
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3792
Cataract induction does not affect hunting behaviour in optimal light conditions (left panels) but causes impairments in challenging light environments (right panels).
منشور في 2025"…Similarly, under bright and UV light, we did not detect differences in hunting success (E,G; <i>n</i><sub><i>control</i></sub> = 12, <i>n</i><sub><i>lens3RNAi </i></sub>= 23, <i>p</i><sub>horizontal</sub> = 0.28, <i>p</i><sub>vertical</sub> = 0.23), but observed a weak (nonsignificant) decrease in the hunting success of treatment individuals under dim white light (F,H; <i>n</i><sub><i>control</i></sub> = 13, <i>n</i><sub><i>lens3RNAi </i></sub>= 22, <i>p</i><sub>horizontal</sub> = 0.22, <i>p</i><sub>vertical</sub> = 0.42).…"
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3793
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3794
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3795
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3796
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3797
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3798
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
منشور في 2025"…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …"
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3799
The minimal data set.
منشور في 2025"…However, the extensive use of insecticides poses a significant threat to the survival and efficacy of <i>T. ostriniae</i>. …"
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3800