Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

"…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …"

Statistical data. حسب Bo Yang (104813)

"…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …"

Sensitivity of land types to threat factors. حسب Bo Yang (104813)

"…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …"

DataSheet1_Updated evidence of the Naoshuantong capsule against ischemic stroke: a systematic review and meta-analysis of randomized controlled trials.docx حسب Cuilin Que (19743256)

"…Background<p>Stroke is a serious health issue that can result in death or disability, leading to a significant economic strain on society and families. …"

Table 1_Unpacking the cost implications of diagnosis-related groups reform for lumbar disc herniation patients in Chinese medicine: a closer look at evidence from China.xls حسب Meng-en Chen (22274533)

"…Objectives<p>Lumbar disc herniation (LDH) presents a significant economic burden globally, worsening in China due to an aging population. …"

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx حسب Ruochen Zhang (3434996)

"…In order to compare N/P efficiency more intuitively, we combined N/P content, N/P uptake, N/P uptake efficiency and N/P recover efficiency to calculate N/P comprehensive efficiency.…"

Data Sheet 1_Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study.pdf حسب Yan Xia (534241)

"…</p>Conclusions<p>Compared with IMRT, TOMO decreases the incidence of radiation pneumonitis but fails to improve acute skin toxicity. …"

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... حسب Neves P.D.M.M. (20408168)

"…The kidney is a frequent target of SARS-CoV-2, potentially developing lesions in glomeruli, vessels, and tubulointerstitium in response to this infection. Herein we present the analysis of the first large Latin American cohort of adult patients undergoing kidney biopsy due to COVID-19-associated kidney disorders. …"

Repetitive stress modulates loudness perception. حسب Ghattas Bisharat (20706928)

"…(c) Perceptual boundaries in different conditions. We define the perceptual boundary as the intensity where the psychometric fit to the choice function, crosses PLoud = 0.5. …"

Table 1_Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort.docx حسب Mary Ngongang Kameni (20924126)

"…Our most significant findings include the association of double mutant alleles (AA) of rs4646140 and rs2074192 in the ace2 gene with decreased IL-6 and IL-2 expression levels respectively in TB-COVID-19 participants. …"

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... حسب Deliang Kong (382201)

"…</p>Results<p>From 2016 to 2022, the incidence rate of PTB in southwest China showed a decreasing trend (AAPC = -10.22, 95% CI: −11.49% ~ −8.94%), while the incidence rate of PTB-DM increased rapidly (AAPC = 14.25, 95% CI: 11.35% ~17.23%). …"

PDLB - Balance Sheet حسب Nguyen Linh (19516642)

"…</p><p><br></p><p dir="ltr">ECIP capital: PDLB received $225M of ECIP capital, and the regulators assigned them the lowest possible dividend (0.5%) on this capital for the first year of payments (announced in June). If we assume PDLB continues to pay 0.5% on this preferred and they have a cost of preferred equity of 10%, then we can calculate the value of this $225M liability as just $11M, with the rest a write-up to equity.…"

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx حسب Mehri Hajiaghayi (19822665)

"…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …"

<i>mig-21</i> sensitizes adult DTCs to polarizing signals. حسب Xin Li (51274)

"…A robust “extra turn” defect rate of control on <i>vab-3</i> RNAi (n=38/57) decreases with <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=24/65), p < 0.01. …"

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” حسب Chanping You (9067448)

"…</p><p><br></p><p dir="ltr">This study investigated the role of AR in chemotherapy response using two AR-positive breast cancer cell lines. We assessed responses to multiple chemotherapeutic agents—palbociclib, docetaxel, doxorubicin, paclitaxel, and cisplatin. …"

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity حسب Mengyu Liu (2890397)

"…<p>Trimethyltin chloride (TMT) is widely used as a constituent of fungicides and plastic stabilizers in the industrial and agricultural fields, and is generally acknowledged to have potent neurotoxicity, especially in the hippocampus; however, the mechanism of induction of neurotoxicity by TMT remains elusive. Herein, we exposed Neuro-2a cells to different concentrations of TMT (2, 4, and 8 μM) for 24 h. …"

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. حسب DIMITRIOS KIMOGLOU (20499350)

"…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …"

Study group background characteristics. حسب Zicheng Hu (3825313)

"…This ratio was disrupted when blood CD4+ T-cells fell to <50 cells/μL and the CSF WBC count decreased to negligible levels; in this group the CSF:blood HIV-1 RNA ratio decreased nearly 10-fold to an overall ratio of <1:100. …"

LRIG1 and CDK6 expression in the lateral ventricular wall cells حسب Hyung-song Nam (8914220)

"…Although the <i>Cdk6</i> mRNA decreases significantly in the neuroblasts, the DCX+ neuroblasts still show a lot of td-sfGFP immunoreactivity.…"

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. حسب Melinda L. Tursky (20790436)

"…The mean number of variants detected per sample above the standard CHIP threshold of ≥ 0.02 VAF increased linearly with subject age (E). Greater than 99.9% of variants detected were below ≥ 0.02 VAF, potentially including those with prognostic or predictive clinical relevance (F). …"