Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”

Insight into Greenhouse Gas Emission Characteristics of Light-Duty Vehicles in China Driven by Technological Innovation by Xinping Yang (17371783)

“…As anticipated, with advancements in emission standards and powertrains, vehicular GHG emissions have significantly decreased. However, our findings also revealed surprising trends. …”

Fig 3 - by Laura Garcia-Toscano (20477540)

“…<p>Hsp90 mutation or inhibition decreases accumulation of phosphorylated TDP-43 <b>A.…”

Data Sheet 1_Antibacterial effects of coniferyl alcohol-derived dehydrogenation polymer on chlamydial infection in vitro.pdf by Anna Pfundner (22409281)

“…Infection and adhesion assays demonstrated a significant reduction in infection levels, suggesting that DHP/Alg directly targets Chlamydia elementary bodies, thereby disrupting their ability to adhere and initiate infection. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…C57BL/6J mice treated with two cycles of cisplatin (3.5 mg/kg) showed a significant elevation in ABR thresholds, along with loss of outer hair cells and inner hair cells synapse. …”

Image 3_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Image 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Table 1_Feeding citrus pomace fermented with combined probiotics improves growth performance, meat quality, fatty acid profile, and antioxidant capacity in yellow-feathered broiler... by Yanchen Liu (3691888)

“…</p>Results<p>The results showed that dietary FCP significantly increased (p < 0.05) the final-body-weight and average-daily-gain of broilers, and the pH_{45 min} and b*_{24 h} values in breast muscle, while tendentiously lowering the feed-to-gain ratio (p = 0.076). …”

Table 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc by Yaojin Sun (21692411)

“…Background<p>Hemophilia, a genetic disorder characterized by deficiencies in clotting factors VIII or IX, often results in joint and muscle bleeding, leading to hemophilic arthropathy and reduced quality of life. …”

Data Sheet 1_Algicidal activity of Streptomyces sp. LMJ-114 against Microcystis aeruginosa.pdf by Mijia Du (18080947)

“…The treatments of both culture broth supernatant and mycelia of strain LMJ-114 significantly affected the contents of retinoic acids (RAs) and microcystins (MCs), and 4 days later, RAs eliminated completely, and 7 days later, microcystin RR (MC-RR) decreased by 96.7 and 87.9%, respectively, and microcystin LR (MC-LR) contents decreased by 89.9 and 81.0%, respectively. …”

Table 1_Ultrasonographic examination of the patellar ligament after capsular and fascial imbrication for the treatment of cranial cruciate ligament rupture in dogs.docx by Mario Candela Andrade (20932802)

“…Thickening of the patellar ligament after capsular and fascial imbrication (CFI) is a frequently reported complication, but its clinical significance remains unclear.…”

Data Sheet 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc by Yaojin Sun (21692411)

“…Background<p>Hemophilia, a genetic disorder characterized by deficiencies in clotting factors VIII or IX, often results in joint and muscle bleeding, leading to hemophilic arthropathy and reduced quality of life. …”

Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx by Yanzheng Xie (22596953)

“…</p>Methods<p>By leveraging the unique long-range focusing capability, we establish a tapered-fiber-probe (TFP) strategy enabling non-contact and highprecision near-infrared (NIR) optical pacing in zebrafish embryos, where sustained micron-scale spatial precision (3 μm FWHM) was achieved at physiologically relevant working distances.…”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Projecting global shifts in the invasive potential of Bidens pilosa L. under climate change using species distribution models.xlsx by Linran Fan (2210911)

“…Our findings suggest a likely decline of suitable habitats in tropical regions and an expansion into temperate regions, with climate suitability decreasing under higher temperatures. …”

Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

“…Furthermore, both QWBZP decoction and QWBZP-TG decreased the levels of DAO, D-Lactate, sIgA, IL-6, and TNF-α in the AAD mice. …”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…Complete blood count (CBC), blood biochemistry, short-chain fatty acids (SCFAs), gut microbiota composition in the colon, and metabolites in the cecum were analyzed.</p> <p>DYY significantly reduced symptom scores and decreased CRP level, while also regulating parameters in CBC and biochemical profiles. …”

Table 2_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

“…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”

Table 1_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

“…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”