Image2_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…We found that ADMA disrupted physical barrier function as evident by significant decrease in electrical resistance and increase in paracellular permeability of hBMVEC monolayers. …”

Image 6_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…Despite their lipopolysaccharide membrane layer, we demonstrate that, in liquid, GCA increases permeability, changes the surface of the Enterobacteriaceae membrane, and compromises its integrity. …”

raw data of "Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming" by Quan Zhang (20376574)

“…Furthermore, we identify that CdtB translocates to mitochondria with the assistance of Hsp90, leading to a decrease in the activity of mitochondrial respiratory complex V due to its interaction with ATP5A1. …”

Raw_data_N_adition_increased_SOC_PNAS.xlsx by Guoyong Yan (14273351)

“…We found that SOC significantly increased with N addition, driven by the combined responses of plants, soil, and microbes. …”

Image 3_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…Despite their lipopolysaccharide membrane layer, we demonstrate that, in liquid, GCA increases permeability, changes the surface of the Enterobacteriaceae membrane, and compromises its integrity. …”

Image 5_The Effect of glycocholic acid on the growth, membrane permeability, conjugation and antibiotic susceptibility of Enterobacteriaceae.pdf by Bar Piscon (20906495)

“…Despite their lipopolysaccharide membrane layer, we demonstrate that, in liquid, GCA increases permeability, changes the surface of the Enterobacteriaceae membrane, and compromises its integrity. …”

Image1_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…We found that ADMA disrupted physical barrier function as evident by significant decrease in electrical resistance and increase in paracellular permeability of hBMVEC monolayers. …”

Table 1_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx by Nianfeng Tang (21536069)

“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”

Table 3_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx by Nianfeng Tang (21536069)

“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”

Table 4_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx by Nianfeng Tang (21536069)

“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”

Table 2_Retinal vessel metric analysis of type 1 diabetes mellitus in OCT angiography.docx by Nianfeng Tang (21536069)

“…In addition, the VD of the inferior parafoveal vein (P = 0.022) and superior parafoveal artery (P = 0.03) were significantly decreased in the NPDR group. Comparing the VD among NDR subgroups and control group, the VD of the superficial inferior parafovea of T1DM patients of early stage (less than 5 years) was significantly lower than that of normal people (p < 0.05), while the VD of the inferior parafoveal artery increased (P = 0.012).…”

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…Additionally, OATD-01-treated mice had lower CHIT1, F4/80, and α-smooth muscle actin positivity, as well as significantly lower levels of inflammatory markers, pro-fibrotic genes, and matrix remodeling-related mRNAs than vehicle-treated mice. …”

CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability by Zhanghui Zeng (3571331)

“…Compared to the wild-type, all mutants displayed normal plant height, tiller number, and grain size, although the <i>loxC1</i> and <i>loxAloxC1</i> mutants exhibited significantly lower thousand grain weights. Notably, the total LOX activity in mature grains decreased by 36–42% in <i>loxC1</i> mutants and by 94% in <i>loxAloxC1</i> mutants, with no significant change observed in <i>loxB</i> mutants. …”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…Additionally, OATD-01-treated mice had lower CHIT1, F4/80, and α-smooth muscle actin positivity, as well as significantly lower levels of inflammatory markers, pro-fibrotic genes, and matrix remodeling-related mRNAs than vehicle-treated mice. …”

Table 1_Assessment of platelet-to-white blood cell ratio on short-term mortality events in patients hospitalized with acute decompensated heart failure: evidence from a cohort stud... by Xin Huang (11077)

“…Further threshold analysis revealed a threshold point for PWR at 15.88, where a decrease in PWR below this threshold was significantly associated with increased risk of all-cause mortality (p for log-likelihood ratio test = 0.046). …”

Data Sheet 1_Dietary supplementation with hydroxy-methionine manganese improves meat quality, antioxidant capacity, and lipid metabolism in Cherry Valley ducks (Anas platyrhynchos... by Yang Liu (4829)

“…Results showed that the 120 mg/kg MnHMet group had significantly lower triglyceride (TG) levels than the MnSO₄ group (P < 0.05). …”

Table_1_Regional and social disparities in cessation behavior and motivation to quit among U.S. adult current smokers, Tobacco Use Supplement to the U.S. Census Bureau's Current Po... by Candon Johnson (11572623)

“…Notably, the Asian non-Hispanic group in the Northeast experienced a significant decrease in quit interest (–17.9%) but an increase in recent successful cessation (+369.2%).…”

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx by Ameya Joshi (1290186)

“…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…”

A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease by Akanksha Chhabra (71080)

“…Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). …”

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…For Kermadec Trench specimens from ~7,000 m, largely undamaged by cool surface waters, Na+ averaged 199 mmol/kg (Yancey et al. 2014), much lower than in seawater (~470 mM). This 199 mmol/kg is higher than in shallow fish, but is expected if TMAO is largely intracellular and is osmotically balanced by higher NaCl in extracellular fluids (as we found for bathyal and abyssal fish). …”