P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). حسب Hong Yan Huang (20135965)

"…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …"

Image 2_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Table 6_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Table 5_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

Image 5_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Image 1_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tiff حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Table 7_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Table 4_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.xlsx حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Image 6_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff حسب M. Firoz Mian (10013314)

"…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …"

Image 4_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif حسب Bin He (75597)

"…These subtypes exhibited significantly different distributions between AF and SR. …"

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... حسب Abdulaziz Almutairi (9584768)

"…What is the specific question(s) we wanted to answer?</b></p><p dir="ltr">· Does MF-iPLA₂b-derived lipid signaling impact diabetes development ?…"

Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx حسب Alexandra Prodea (22617710)

"…The toxicity assessment revealed that triterpenes have in general, insignificant or absent toxicity, with only a small number of studies reporting serious side effects such as leukopenia, hepatotoxicity and mortality at specific doses that were reversed in some cases by the use of carriers, which hold the potential to enhance the therapeutic effect of triterpenes while reducing their systemic toxicity.</p>Conclusion<p>We concluded that the current in vivo evidence does not support the clinical translation of triterpenes for the treatment of breast cancer due to methodological and clinical heterogeneity as well as the lack of toxicity data in a significant number of studies. …"

Table 1_Impact of the Yangtze River on Sediment source-to-sink processes in estuarine bays: a study of the Oujiang River Estuary, SE China.docx حسب Xia Guang (21570056)

"…Our findings revealed a dynamic pattern of sediment distribution, with the predominant clay minerals in the surface sediment of the offshore area being illite, followed by kaolinite and chlorite, with a minor smectite content. Notably, we observed a gradual increase in the proportions of illite and smectite from the upstream to the estuary, while kaolinite decreased accordingly. …"

Data Sheet 1_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.pdf حسب Alexandra Prodea (22617710)

"…The toxicity assessment revealed that triterpenes have in general, insignificant or absent toxicity, with only a small number of studies reporting serious side effects such as leukopenia, hepatotoxicity and mortality at specific doses that were reversed in some cases by the use of carriers, which hold the potential to enhance the therapeutic effect of triterpenes while reducing their systemic toxicity.</p>Conclusion<p>We concluded that the current in vivo evidence does not support the clinical translation of triterpenes for the treatment of breast cancer due to methodological and clinical heterogeneity as well as the lack of toxicity data in a significant number of studies. …"

Data Sheet 1_Impact of a structured food sequence and mobile health monitoring on gestational diabetes outcomes: a clinical trial.pdf حسب Ria Murugesan (21795620)

"…A p-value <0.05 was considered statistically significant.</p>Results<p>The intervention group showed significant reductions in 1-h and 2-h postprandial blood glucose levels (−8.41 mg/dL and −7.56 mg/dL respectively, both p < 0.001), decreased LDL cholesterol (−7.33 mg/dL, p < 0.001), increased HDL cholesterol (+6.15 mg/dL, p < 0.001), and improved hemoglobin levels. …"

Table 1_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx حسب Francesco Campa (20997323)

"…Aging was associated with increased R/H and decreased phase angle, whereas older individuals with higher ALSM exhibited a greater phase angle and lower R/H, and Xc/H. …"

Table 2_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx حسب Francesco Campa (20997323)

"…Aging was associated with increased R/H and decreased phase angle, whereas older individuals with higher ALSM exhibited a greater phase angle and lower R/H, and Xc/H. …"

Data Sheet 1_Unveiling frailty: comprehensive and sex-specific characterization in prematurely aging PolgA mice.pdf حسب Dilara Yılmaz (19710658)

"…While these approaches have been applied to aging mice, their effectiveness in prematurely aging mouse models such as PolgA^D257A/D257A (PolgA) has not been completely explored. We demonstrated that frailty became evident in PolgA mice around 40 weeks, validated through body weight loss, reduced walking speed, decreased physical activity, and weaker grip strength. …"