Docetaxel and quercetin-loaded lipid nanocarrier optimized by quality by design for glioblastoma therapy: a ligand-conjugated and therapeutic repurposing approach by Zufika Qamar (22259678)

“…Compared to non-conjugated NLC and (DTX-QUR) suspension (SUS), Tf-(DTX-QUR) NLC showed 3.6- and 5.8-fold decrease in IC₅₀, respectively. Cellular uptake studies demonstrated significantly (<i>***p < 0.001</i>) high internalization of Tf-conjugated NLC to U87-MG cells. …”

Table 1_Interobserver variability in organ delineation on radiotherapy treatment planning for nasopharyngeal carcinoma: A dosimetric and prognostic analysis.docx by Meining Chen (18693919)

“…Compared to standard delineations, all four physicians showed decreased TCPs (average decrease in ΔTCP >1%) and a significant increase in NTCPs of OARs. …”

PCAIs disrupt actin filaments in NCI-H23 cells. by Matthew D. Gregory (19929096)

PCAIs inhibit NCI-H23 cell line viability. by Matthew D. Gregory (19929096)

“…However, CRAF/RAF1 phosphorylation decreased by 40%, suggesting significant changes in the KRAS/MAPK signaling patterns. …”

PCAIs disrupt actin filaments in NCI-H23 cells. by Matthew D. Gregory (19929096)

“…However, CRAF/RAF1 phosphorylation decreased by 40%, suggesting significant changes in the KRAS/MAPK signaling patterns. …”

PCAIs suppress 3D NCI-H23 cell invasion. by Matthew D. Gregory (19929096)

“…However, CRAF/RAF1 phosphorylation decreased by 40%, suggesting significant changes in the KRAS/MAPK signaling patterns. …”

PCAIs suppress NCI-H23 cancer cell migration. by Matthew D. Gregory (19929096)

“…However, CRAF/RAF1 phosphorylation decreased by 40%, suggesting significant changes in the KRAS/MAPK signaling patterns. …”

PCAIs induce apoptosis in NCI-H23 cells. by Matthew D. Gregory (19929096)

“…However, CRAF/RAF1 phosphorylation decreased by 40%, suggesting significant changes in the KRAS/MAPK signaling patterns. …”

The effect of PCAIs on BRAF and RAF1 (CRAF) protein phosphorylation. by Matthew D. Gregory (19929096)

TRV-based silencing of <i>NbGAPCs</i> in <i>Nicotiana benthamiana</i> plants. by Yongle Zhang (11355546)

CTV p20 interacts with NbSGS3 and mediates autophagic degradation of NbSGS3. by Yongle Zhang (11355546)

Effects of activators and inhibitors on TcPiezo channels. by Guozhong Huang (673424)

“…Downregulation of <i>TcPiezo2</i> expression (+Tet) showed a significant decrease of lysosomal Ca²⁺ release as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1013105#ppat.1013105.g004" target="_blank">Fig 4A</a>. …”

TRV-based silencing of <i>NbATG5</i> and <i>NbATG7</i> in <i>Nicotiana benthamiana</i> plants. by Yongle Zhang (11355546)

The effect of PCAIs on MAPK pathway protein phosphorylation. by Matthew D. Gregory (19929096)

Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study by Emiko Otsuka (7519313)

“…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …”

MST1 upregulates CD36 expression via PPARγ. by Jianyang Li (461703)

Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx by Luana Pulvirenti (2925741)

“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”

Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx by Luana Pulvirenti (2925741)

“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”

Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_Urinary and oral microbiota in Polish women: a pilot case-control study of breast cancer.docx by Anna Marciniak (12354534)

“…</p>Results<p>BC case urine microbiota contained an increased abundance of Corynebacterium (5.2-fold, but not significant) and Gammaproteobacteria including unknown genus and Pseudomonas (1.7- and 1.8-fold) and decreased abundance of Family XI (0.3-fold) and Bifidobacteriaceae (0.4-fold) compared to HCs. …”