Data Sheet 3_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Image2_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Table1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Table3_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Data Sheet 1_A new strategy improving TB diagnosis: stratified urine LAM test based on lymphocyte counts.docx حسب Hongzhi Li (271473)

"…For patients with lymphocyte counts <0.8 × 10⁹/L, the cost of AIMLAM was further reduced to $67.84 (a 47.74% decrease), which was lower than GeneXpert ($111.65) and sputum culture ($94.28).…"

Dynamic functional connectivity changes in left DLPFC-tDCS protocol (F3a-Fp2c). حسب Yanqing Dong (8829548)

"…Warmer colors indicate an increase in FC, while cooler colors indicate a decrease in FC. Color bars indicate statistical t-values ().…"

Supplementary Material for: Innovative regenerative treatment with Nanofat injection for hypertensive ischemic leg ulcer: a case report حسب figshare admin karger (2628495)

"…Pain management was significantly improved, with the visual analog scale (VAS) decreasing from 8/10 to 0/10 within seven days. …"

Data Sheet 1_The CaSBP11 gene functions as a negative regulator in pepper drought stress.doc حسب Huai-Xia Zhang (8493453)

"…Conversely, overexpression of CaSBP11 in Nicotiana benthamiana decreased drought tolerance, with CaSBP11-overexpressing plants showing reduced ABA sensitivity, lower stomatal aperture and ABA levels, and increased stomatal density and ROS production compared to wild-type plants. …"

Diagnostic utility of cytomorphometric evaluation of exfoliated buccal mucosal cells in age estimation: a systematic review and meta-analysis حسب R Keerthika (21338964)

"…Twelve studies, and two subgroups included for qualitative and quantitative data synthesis, revealed a significant decrease in cellular parameters and an increase in nuclear parameters in healthy individuals as age progressed. …"

DataSheet1_Accumulation of coumaric acid is a key factor in tobacco continuous cropping obstacles.docx حسب Meng Jia (696568)

"…Introduction<p>Phenolic acids are believed to play a significant role in tobacco continuous cropping obstacles, but the strength and potential mechanisms of different phenolic acids remain unclear.…"

Photon budgets and the effects of relative CDOM and pigment absorptions on primary production along a coastal salinity gradient حسب Aleksandr Berezovski (20459366)

"…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …"

Image 1_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.png حسب Adalyat Alenova (22696712)

"…In contrast, the composite prognosis score demonstrated a strong positive correlation with treatment success (r = 0.578; p < 0.0001).…"

Image 2_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.jpeg حسب Adalyat Alenova (22696712)

"…In contrast, the composite prognosis score demonstrated a strong positive correlation with treatment success (r = 0.578; p < 0.0001).…"

Data Sheet 1_Preclinical evidence for luteolin in ulcerative colitis: a meta-analysis and systematic review.docx حسب Yiyi Feng (12530035)

"…</p>Results<p>The meta-analysis revealed that LUT significantly ameliorated colon length, reduced the disease activity index, alleviated body weight loss, and decreased histological scores. …"

Table 1_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.docx حسب Mohamed E. A. Mostafa (19834779)

"…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …"

Table 2_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.xlsx حسب Mohamed E. A. Mostafa (19834779)

"…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …"

Data Sheet 1_Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study.pdf حسب Kaiwen Wang (838527)

"…</p>Results<p>There was no causal relationship between sex hormones and IBD in women (P > 0.05), and there was a causal and positive correlation between SHBG and testosterone and IBD in men.The OR for SHBG was 1.22 (95% CI: 1.09-1.37, P = 0.0004), and for testosterone was 1.20 (95% CI: 1.04-1.39, P = 0.0145).IBD did not significantly interact with female sex hormones but resulted in a decrease in SHBG (OR = 1.02, 95% CI: 1.00-1.04, P = 0.0195) and testosterone (OR = 1.01, 95% CI: 1.00 -1.02, P = 0.0200) in men.…"

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer حسب Chen Zhang (66790)

"…<p>Despite surgical and intravesical chemotherapy interventions, non-muscle invasive bladder cancer (NMIBC) poses a high risk of recurrence, which significantly impacts patient survival. …"