Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…<p dir="ltr"><b>I</b><b>NTRODUCTION</b></p><p dir="ltr">Trimethylamine N-oxide (TMAO) is a small organic molecule found at osmotically-significant concentrations in many marine animal taxa. …”

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... by Jing Lu (120666)

“…Following multivariable adjustment, lower SI was associated with an increased risk of all-cause and cardiovascular mortality in CVD patients. …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf by Jiatao Li (10033795)

“…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …”

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... by Jia-Wei Feng (10754067)

“…</p>Results<p>Logistic regression identified five independent clinical risk factors: maximum tumor diameter, multiple lesions, upper pole location, decreased monocyte count, and lower lymphocyte-to-monocyte ratio (LMR). …”

Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d... by Sathivel Thivijan (20393742)

“…The combined attributes of H. uvarum higher alcohol content, enhanced fruity notes, improved clarity, lower acetic acid (0.52 ± 0.03 g L⁻¹), and significant residual sugar (162.37 ± 2.48 g L⁻¹) make it a promising candidate for improving the overall quality of regional wines. …”

Data Sheet 1_Synchronized nutrition fertilizer improves soil microbial diversity and sugarcane yield through agrochemical and enzymatic regulation.docx by Xiuxiu Qi (22354858)

“…</p>Results<p>Results showed that yield, °Brix in the SNFert, even with 15% and 25% less fertilizer input, were no significant differences with those of CF. Specifically, SNF1 increased sugarcane yield and tillers by 6.84% and 18.63%, raised pH and urease by 0.40 units and 2.29 times, reduced Nmin and EC by 81.69% and 77.69% with 15% lower fertilizer input, respectively. …”

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx by Qingqing Zhuang (22109089)

“…Serum sGFAP decreased from 278.0 to 130 pg/mL (p = 0.027), while sNfL levels transiently increased before stabilizing. …”

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF by Yury Maritza Zapata-Lopera (19725616)

“…They prevent the activation of iNOS and nNOS, reducing harmful reactive oxygen and nitrogen species, and boosting antioxidant enzymes like catalase and superoxide dismutase. This lowers oxidative stress and decreases the expression of proteins and genes linked to cell death, such as Bax, Bcl-2, and caspase-3. …”

Ameliorating role of co-administration of granulocyte colony stimulating factor and sodium bicarbonate on the skeletal muscle of a rat model of chronic kidney disease (A histologic... by Fayza E. Ahmed (20487163)

“…The CKD group revealed a significant increase in MDA and TNF-α. Furthermore, features of renal injury, muscle degenerative changes, increased collagen and decreased CD34 and myogenin expression were observed. …”

Data Sheet 1_Deep learning-based image reconstruction benefits diffusion tensor imaging for assessing severity of depression.docx by Yuanyuan Cui (276987)

“…Compared to patients with mild-to-moderate depression, those with severe depression showed lower FA values in the right corticospinal tract (CST) on ORI DTI. …”

Table 1_Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia).docx by Katarína Pukanská (20431835)

“…</p>Results<p>Between 2018 and 2023, the ice volume in certain sections of the cave decreased by up to 667 m³, with notable reductions in ice thickness ranging from 0.3 to 0.9 m in areas like the Small Hall and Collapsed Dome. …”

Supplementary Material for: Diverse Obesity Trajectories in a Family including Identical Twins with a Pathogenic MC4R Variant by figshare admin karger (2628495)

“…Twin 1 had a peak BMI of 29.1 kg/m2, which decreased to 19.7 kg/m2 with intensive exercise and diet control without weight-lowering medication. …”

Image 2_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Image 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Table 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Image 10_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Image 7_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”