Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip حسب Yupeng Li (507508)

"…Atorvastatin enhanced the antioxidant capacity of NPCs and decreased intracellular ROS accumulation. It promoted Nrf2 activation and upregulated the expression of downstream antioxidant factors, thereby exerting a protective effect against oxidative stress–induced injury. …"

Table 1_Ayahuasca partially preserves striatal integrity in juvenile non-human primates exposed to chronic stress: evidence from stereological evaluation.docx حسب Wigínio Gabriel de Lira-Bandeira (20749421)

"…It may undergo several morphophysiological changes in neuropsychiatric diseases. Depression, a complex psychiatric disorder, affects millions of people around the world and leads to an increased risk of suicide, decreased quality of life, and functional impairment. …"

Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx حسب Haipeng Zhang (3413288)

"…Four hub genes—SRC, TLR8, FCAR, and HIF1A—were identified using LASSO and RF algorithms. …"

Image_2_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... حسب Huan Xiang (460100)

"…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…"

Image_1_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... حسب Huan Xiang (460100)

"…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…"

<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... حسب Kangning Yan (22751487)

"…Furthermore, aboveground Si content decreased significantly from leaves (10.54–21.45 g kg–1) to branches (3.81–5.61 g kg–1) and culms (1.07–1.98 g kg–1). …"

Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip حسب Shuxian Pan (8868356)

"…Based on machine learning-selected indicators, antiviral therapy and The HBV DNA copy number showed a significant correlation with both the occurrence and severity of irAEs. …"

Hypoxia response and tracheogenesis in <i>PGR</i> mutants. حسب Daiki Fujinaga (21301129)

"…<p>(A) Relative expression levels of <i>branchless</i> (<i>bnl</i>) in <i>PGR</i> mutants from 0 to 96 hours after puparium formation (APF). …"

DataSheet1_Leaf functional traits highlight phenotypic variation of two tree species in the urban environment.docx حسب Ahram Cho (20437850)

"…The leaf functional traits of Norway Maple and Little − leaved Linden were studied in three locations in the summer of 2023: an urban park (University of Illinois Chicago, Chicago, IL), a suburban park (Morton Arboretum, Lisle, IL), and a suburban residential site (Lombard, IL). …"

Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation حسب Chenfei Li (5921768)

"…<p>This study aims to investigate the protective effects and mechanisms of 20S-protopanaxadiol (PPD), a key component derived from ginseng folium, against diabetic nephropathy (DN).…"

Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z... حسب Peng Ren (337555)

"…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…"

Data Sheet 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.pdf حسب Rui Jiang (264894)

"…This study aimed to investigate the therapeutic potential of exosomes derived from human classical interscapular brown adipocytes (hcBAC-exos) in alleviating symptoms of RA in a mouse model.</p>Methods<p>We established a mouse model of collagen-induced arthritis (CIA) to evaluate the efficacy of hcBAC-exos. …"

Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx حسب Xiongbao Wang (12508462)

"…Therefore, LAMP1 emerges as a novel biomarker associated with the diagnosis and prognosis of renal cancer. …"

Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"

Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"

All data. حسب Ke Li (106849)

"…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …"

The relationship between early-onset preeclampsia and the prognostic nutritional index and inflammatory markers حسب Alev Esercan (19818890)

"…</p> <p>In our case control study, 70 patients with early-onset preeclampsia and 140 pregnant women composed the normotensive (control) group. There was a significant difference between the groups according to PIV (p = 0.04). …"

Data Sheet 1_Mobility status, nutritional intervention and meal eaten are associated with discharge home: the nutritionDay study in China.docx حسب Bei Zhou (5219792)

"…Mobile patients who could walk unaided had a 1.2 to 1.3 times higher chance of discharge home and a significantly shorter duration of hospital stay after nutritionDay than those with reduced mobility, especially in patients receiving artificial nutrition (median: 8 days vs. 11 days, p < 0.001) and those with incomplete meal intake (median: 6 days vs. 8 days, p < 0.001). …"

Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif حسب Wei Liu (20030)

"…In vitro, KSG mitigated Aβ_25-35-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …"

Fine mapping of the <i>PSV1</i> locus implicates the mitotic cell cycle regulator <i>DUO3.</i> حسب Matthew T. Parker (10217926)

"…Sperm nuclei that inherit the Db-1 haplotype of <i>PSV1</i> have significantly increased expression of <i>UBC20</i> and decreased expression of <i>CYCB1;2</i>, compared to sister nuclei that inherit the Col-0 haplotype. …"