يعرض 6,841 - 6,860 نتائج من 8,845 نتيجة بحث عن 'significantly ((((mean decrease) OR (we decrease))) OR (greatest decrease))', وقت الاستعلام: 0.46s تنقيح النتائج
  1. 6841

    The PCR primers for 4C-seq library construction. حسب Tingting Jiang (169999)

    منشور في 2025
    "…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"
  2. 6842

    Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts حسب Kevin E. Ayala (21979064)

    منشور في 2025
    "…</p> <p>We report that voriconazole and posaconazole are highly effective in all host backgrounds tested, while isavuconazole and itraconazole exhibit host-specific efficacy and toxicity. …"
  3. 6843

    Data Sheet 1_Impact of multiple environmental factors on influenza–like illness in Fujian Province, China, 2015–2023: a multicity study.zip حسب Xiaoyan Yao (8723622)

    منشور في 2025
    "…Introduction<p>Influenza-like illness (ILI) represents a significant global public health challenge influenced by environmental factors. …"
  4. 6844

    Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx حسب Hui Li (32376)

    منشور في 2025
    "…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …"
  5. 6845

    Table 1_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

    منشور في 2025
    "…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"
  6. 6846

    Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls حسب Wenyong Liao (21669332)

    منشور في 2025
    "…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…"
  7. 6847

    Image 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.tif حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"
  8. 6848

    Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf حسب Mallory A. Perry-Eaddy (20842868)

    منشور في 2025
    "…</p>Methods<p>We conducted a post hoc secondary analysis of the MitoPSe clinical study, including N = 119 critically ill children who survived sepsis. …"
  9. 6849

    Table 4_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

    منشور في 2025
    "…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"
  10. 6850

    Table 1_Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer.xlsx حسب Xiucheng Jiang (18849564)

    منشور في 2025
    "…Notably, mitochondrial haplogroup D4 was significantly associated with a decreased risk of developing EC. …"
  11. 6851

    Image 2_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg حسب Kaisong Huang (5412626)

    منشور في 2024
    "…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …"
  12. 6852

    Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 حسب Adam Eckardt (20573576)

    منشور في 2025
    "…Bet1L knockdown decreased motor neuron size in the lumbar spinal cord, which innervated the siRNA-injected hindlimb. …"
  13. 6853

    Data Sheet 3_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"
  14. 6854

    Table 4_Impact of prior exposures on biomarkers of blast during military tactical training.xlsx حسب Zhaoyu Wang (3059889)

    منشور في 2025
    "…Aβ40 and Aβ42 levels were significantly decreased in response to blast at the follow-up (~16 h) LLB exposure timepoint, concomitant with elevated expression of genes involved in amyloid-beta regulation and clearance in SMs with mTBI.…"
  15. 6855

    Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

    منشور في 2025
    "…Cellular experiments further investigated the expression of cholesterol metabolism-related proteins and the effect of the cholesterol-depleting agent Methyl-β-cyclodextrin (MβCD) on DLBCL cells.</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …"
  16. 6856

    <b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b> حسب Rasimcan Meral (5022425)

    منشور في 2025
    "…We have recently shown that glucagon-like peptide-1 agonists are associated with metabolic improvements in FPLD. …"
  17. 6857

    Table 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"
  18. 6858

    Data Sheet 1_Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis.docx حسب Yiwen Wang (666361)

    منشور في 2024
    "…Network analysis showed that the positive correlation with GC-enriched bacteria increased, and the positive correlation with GC-depleted bacteria decreased compared to healthy individuals. Functional analyses indicated that pathways related to carbohydrate metabolism were significantly enriched in GC, while biosynthesis of unsaturated fatty acids was diminished. …"
  19. 6859

    Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 حسب Adam Eckardt (20573576)

    منشور في 2025
    "…Bet1L knockdown decreased motor neuron size in the lumbar spinal cord, which innervated the siRNA-injected hindlimb. …"
  20. 6860

    Table 7_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx حسب Miguel Ângelo-Dias (20936444)

    منشور في 2025
    "…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"