Supplementary Material for: Efficacy and safety of transdermal medical cannabis (THC:CBD: CBN formula) to treat painful diabetic peripheral neuropathy of the lower extremities by Seevathee K. (20196534)

“…Conclusion: This novel transdermal medical cannabis formulation (THC:CBD:CBN) demonstrated significant therapeutic efficacy in ameliorating painful DPN symptoms while maintaining a favorable safety profile. …”

Data source and description. by Yunxia Zhang (30848)

“…The results show that: (1) the level of non-grain of cultivated land in Lianyungang City increased gradually from 6.01% to 11.10% from 2002 to 2022, and grain cultivation was mainly shifted to greenhouse vegetables, construction and development and abandonment. (2) the level of non-grain of cultivated land showed a spatial pattern of high along the north-west-south-east and decreasing to the two sides, and the pattern showed a trend of gradual weakening, with Moran’s I decreased from 0.90 to 0.42. (3) The dominant factors of the spatial differentiation of non-grain of cultivated land in different periods are different, among which GDP, population density, NDVI, and precipitation are always the main influencing factors. …”

Analytical framework. by Yunxia Zhang (30848)

“…The results show that: (1) the level of non-grain of cultivated land in Lianyungang City increased gradually from 6.01% to 11.10% from 2002 to 2022, and grain cultivation was mainly shifted to greenhouse vegetables, construction and development and abandonment. (2) the level of non-grain of cultivated land showed a spatial pattern of high along the north-west-south-east and decreasing to the two sides, and the pattern showed a trend of gradual weakening, with Moran’s I decreased from 0.90 to 0.42. (3) The dominant factors of the spatial differentiation of non-grain of cultivated land in different periods are different, among which GDP, population density, NDVI, and precipitation are always the main influencing factors. …”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Psychometric analysis of the social connectedness instrument.docx by Brian Kelley (1271004)

“…Introduction<p>Social connectedness is decreasing, especially among young adults, which poses a significant public mental and physical health threat globally. …”

Supplementary file 1_Monitoring the dual-season hydrological dynamics of the Pong reservoir in Himachal Pradesh, India.docx by Rajesh Sarda (13162317)

“…The study employed a spatial linear trend modelling approach to identify trends in relative water depth, revealing a decreasing trend and a quantifiable reduction in the reservoir’s depth for both seasons. …”

Table 1_Global burden of disease changes related to high red meat diets and breast cancer from 1990 to 2021 and its prediction up to 2030.docx by Yujun Tong (6179414)

“…Stratification by Socio-Demographic Index (SDI) revealed a significant decline in disease burden in high-SDI regions, while the ASR in low-SDI regions trended upward. …”

<b>Efficacy of strength and conditioning training on dance injury, physical fitness and dance performance in Chinese pre-professional dancers</b> by Matthew Wyon (11437009)

“…The intervention group also demonstrated lower weekly injury prevalence (28% vs 15%, p<0.001) and injury incidence (8.09 vs 5.16 injuries per 1000hrs, p<0.05) during the intervention period compared to their own injury just a year earlier. Conclusion: Strength and conditioning training improved physical fitness levels and decreased the risk of injury in pre-professional dancers, without detrimentally affecting dance performance</p>…”

Supplementary file 1_Collaborative optimal operation control of HVAC systems based on multi-agent.docx by Chen Fu (165356)

“…<p>The HVAC system of public buildings, as a thermostatically controlled load, accounting for a relatively significant proportion of building energy consumption. …”

<b><i>N</i></b>^{<strong>6</strong>}<b>-Methyladenosine demethylase FTO controls</b><b>macrophage homeostasis in diabetic vasculopathy</b> by Siguo Feng (19924429)

“…<p dir="ltr"><b>Abstract</b></p><p dir="ltr">Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playing a pivotal role in the progression of these complications. …”

DataSheet1_Effects of fertilization on litter decomposition dynamics and nutrient release in orchard systems.docx by Huayue Nie (20385747)

“…<p>Plant litter decomposition is a significant ecosystem function that regulates nutrient cycling, soil fertility, and biomass production. …”

Alcohol perceptions and driving decisions among adolescents: Exploring the role of peer and parental influences in Virginia by Asmaa Namoos (21304297)

“…Though parent distracted driving positively influenced adolescent driving behavior, this effect was not statistically significant (coefficient = 0.008, <i>P</i> = .320).</p> <p>The findings indicate a significant reduction in risky behaviors such as drinking and driving and an increase in seat belt use among adolescents. …”

Data Sheet 1_Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations.pdf by Shuang Hu (182425)

“…With the decomposition of leaf litter, the total N content increased gradually, while other nutrients (C, P, K, cellulose and hemicellulose) decreased progressively. Litter characteristics had significant effects on microbial community structure: C/N, TK and residual hemicellulose (RH) were the primary driving factors affecting fungal community structure, whereas bacterial community structure was influenced by TK, RH, residual cellulose (RC) and lignin contents.…”

GPCR kinase, <i>Ppa</i>-GRK-2 is required for light avoidance. by Kenichi Nakayama (2354653)

“…<i>Ppa-grk-2</i> mutants had decreased light avoidance. One-way ANOVA, Dunnett’s multiple comparison tests, compared with wild type. n.s = not significant, ***<i>P</i> < 0.001, ****<i>P</i> < 0.0001.…”

PVD neurons show reduced lysosome function during aging and in the <i>hlh-30</i> mutant. by Ruiling Zhong (22339779)

“…<p><b>(A–D)</b> A fluorescent reporter for luminal acidity of neuronal lysosomal compartments shows that acidity decreases with aging and in the <i><i>hlh-30</i></i> mutant. …”

Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation. by Stefanos Giannakopoulos (15628394)

“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”

Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”

Changes in the separation and spread of evidence distributions induced by energy, contrast, and variability manipulations. by Medha Shekhar (19502698)

“…Note that the energy results in both panels are equivalent to the 4-layer CNN results from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012578#pcbi.1012578.g003" target="_blank">Fig 3</a>. …”

Routine blood biochemical biomarkers in amyotrophic lateral sclerosis: Systematic review and cohort analysis by Robert J. Nona (18558903)

“…To provide further information about the roles of these four biomarkers roles we performed a systematic review. In addition, we also performed a new study of the role of these biomarkers in predicting survival, using data from our local ALS cohort. …”

Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer by Lisa N. Chesner (19677087)

“…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …”