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18181
Data Sheet 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.pdf
Published 2025“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”
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18182
Data Sheet 1_Genome-wide development of SSR molecular markers for modern sugarcane cultivars.docx
Published 2025“…In this study, We searched for and identified SSR loci within the genomes of 14 Poaceae plants. Notably, a significant positive correlation (r = 0.958) was detected between genome size and the number of SSRs. …”
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18183
Table 2_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx
Published 2025“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”
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18184
Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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18185
Dynamic visualization of DNA methylation in cell cycle genes during iPSC cardiac differentiation
Published 2024“…<p>Existing analyses with conventional assays have generated significant insights into static states of DNA methylation but were unable to visualize the dynamics of epigenetic regulation.…”
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18186
Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i>
Published 2024“…Knockout strains of single BbNoxA, BbNoxB, BbNoxR, and double BbNoxA and BbNoxB were constructed via homologous recombination, and their phenotypic characteristics were examined. …”
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18187
Aquaporin and red cell O2 permeability
Published 2025“…The permeability of human and mouse red cell membranes for oxygen”</p><p dir="ltr">Abstract It has been demonstrated that aquaporin-1 (AQP1), one of the most abundant red cell membrane proteins, constitutes a functionally important channel for CO2 in red cell membranes. …”
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18188
Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf
Published 2025“…The known fusion KANSL1-ARL17A/B occurred with a high frequency in 69% of the patients. …”
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18189
Workflow of the study.
Published 2025“…<div><p>Immune dysregulation is a pathogenic factor in ulcerative colitis (UC), in which mitochondrial involvement is increasingly recognized. …”
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18190
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
Published 2025“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. …”
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18191
<b>Canagliflozin-induced adaptive metabolism in bone</b>
Published 2025“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”
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18192
Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario
Published 2025“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”
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18193
Image 2_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18194
Image 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18195
Table 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18196
Image 10_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18197
Image 7_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18198
Table 1_The mechanism of Guanxin Qiwei dropping pills target Dubosiella to improve atherosclerosis.docx
Published 2025“…The correlation analysis further demonstrated a significant positive correlation between Dubosiella and the aforementioned metabolites.…”
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18199
Table 5_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.docx
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”
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18200
Image 4_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf
Published 2025“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”