Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders by Santosh Kumar Rai (22382996)

“…We have developed a potent GPR119 agonist, MKP10241, which has elevated cyclic adenosine monophosphate (cAMP) levels in the GPR119 expressing cell line and reduced blood glucose levels and HbA1c in acute models and a chronic diabetic mouse model. …”

Table 1_Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.docx by Jian Song (4232)

“…</p>Results<p>The results showed that mice with short-term exposure to a high-humidity environment showed a significant increase in the expression of AQP3 and a significant decrease in the expression of AQP4 in the colon, and the TLR4/NF-κb/IL-6 pathway was activated. …”

Data Sheet 2_Forecasting the production and export of shrimp in Bangladesh: a policy focused time series analysis.docx by Mobin Hossain Shohan (21495368)

“…The VAR(1) model predicts a slight decline in production by 2026–27, with exports potentially decreasing by a factor of 3.2 compared to 2010–11. …”

Data Sheet 1_Forecasting the production and export of shrimp in Bangladesh: a policy focused time series analysis.docx by Mobin Hossain Shohan (21495368)

“…The VAR(1) model predicts a slight decline in production by 2026–27, with exports potentially decreasing by a factor of 3.2 compared to 2010–11. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…”

Data Sheet 1_The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms.docx by Xuefeng Sun (408801)

“…Background<p>Sleep is vital for physical and mental health, yet sleep deprivation is a widespread issue that may impair cognitive flexibility, leading to rigid thinking and slower decision-making. …”

Data Sheet 1_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…We present a fifth case of duodenal obstruction due to two congenital bands and provide a comprehensive literature review summarizing the clinical features of this condition.…”

Data Sheet 2_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…We present a fifth case of duodenal obstruction due to two congenital bands and provide a comprehensive literature review summarizing the clinical features of this condition.…”

Data Sheet 3_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…We present a fifth case of duodenal obstruction due to two congenital bands and provide a comprehensive literature review summarizing the clinical features of this condition.…”

Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Importantly, no significant side effects of the p62-plasmid during the whole treatment period were observed.…”

Video 3_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Importantly, no significant side effects of the p62-plasmid during the whole treatment period were observed.…”

Video 1_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Importantly, no significant side effects of the p62-plasmid during the whole treatment period were observed.…”

Exploring the dynamics of gut microbiota, antibiotic resistance, and chemotherapy impact in acute leukemia patients: A comprehensive metagenomic analysis by Ying Luo (381053)

“…Pre- and post-chemotherapy stool samples from patients revealed alterations in microbial richness, taxa, and antibiotic resistance genes (ARGs). The analysis revealed a decreased alpha diversity, increased dispersion in post-chemotherapy samples, and changes in the abundance of specific bacteria. …”

Supplementary Material for: The value of circulating tumor DNA in the prognostic diagnosis of bladder cancer: a systematic review and meta-analysis by figshare admin karger (2628495)

“…PLR and NLR were 2.8 (95% CI: 1.24-6.35) and 0.43 (95% CI: 0.28-0.65), respectively, with a DOR of 6.56 (95% CI: 2.12-20.33).Fagan plot analysis showed that the posterior probability of a positive result rose to 74% and the posterior probability of a negative result decreased to 30% when the prior probability was 50%. …”

Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

Figure 5 from Phenoscaping Reveals Multimodal γδ T-cell Cytotoxicity as a Strategy to Overcome Cancer Cell–Mediated Immunomodulation by Callum Baird Nattress (22619143)

“…<p>B7-H3 mAb facilitates Fc receptor–dependant ADCC by stIL15-γδ T cells. <b>A,</b> Therapeutic apoptosis by stIL15-γδ T cells ± mAb ± mAb (Fc null), against colorectal cancer PDO 141. …”

The long-term <i>in vitro</i> surrogate bacterial viability of canine and feline FMT products frozen at -80°C for six months. by Nina K. Randolph (21030732)

“…<p>All canine FMT products exhibited a significant decrease in overall bacterial viability at the six-month timepoint. …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…This work not only reports the direct nanopatterning of titanium oxide materials but also provides a step-by-step cross-linkable group functionalization strategy to enhance their lithography applications.…”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…This work not only reports the direct nanopatterning of titanium oxide materials but also provides a step-by-step cross-linkable group functionalization strategy to enhance their lithography applications.…”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

“…This work not only reports the direct nanopatterning of titanium oxide materials but also provides a step-by-step cross-linkable group functionalization strategy to enhance their lithography applications.…”