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9001
Data Sheet 2_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.xlsx
Published 2025“…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. We investigated the effects of intermittent and Ramadan fasting on the gut microbial composition, diversity, and short-chain fatty acid (SCFA) profile in a Pakistani population.…”
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9002
Data Sheet 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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9003
Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc
Published 2025“…The number of bacterial keystone taxa was first increased and then decreased, with Bacillota (formerly Firmicutes) being the dominant keystone phylum. …”
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9004
Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx
Published 2025“…Background<p>Preclinical and clinical research of insulin resistance and glucose homeostasis in metabolic disorders are essential. In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…”
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9005
Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”
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9006
Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf
Published 2025“…Introduction<p>We investigated the influence of genetic material and light spectrum on plant performance of two cultivars of potato (Solanum tuberosum L.), ‘Colomba’ and ‘Libra’, grown in greenhouse, in the view of future plant cultivation in Space and terrestrial vertical farming and controlled environment agriculture under limiting light conditions.…”
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9007
Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri...
Published 2025“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”
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9008
Data Sheet 1_A novel bivariate nomogram for predicting sequela vaginal lesions after surgery in patients with HPV-associated cervical cancer.docx
Published 2025“…Then we built three predictive models; multiple logistic regression was optional, with its AUC at 0.7955 in the ROC curve.…”
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9009
Data Sheet 1_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.csv
Published 2025“…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. We investigated the effects of intermittent and Ramadan fasting on the gut microbial composition, diversity, and short-chain fatty acid (SCFA) profile in a Pakistani population.…”
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9010
Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx
Published 2025“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”
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9011
The impact of chronic pain on the quality of life of patients attending soshanguve community health centre (CHC), Tshwane district, South Africa
Published 2025“…<p dir="ltr">Background: Chronic pain poses a considerable challenge to individuals' well-being, leading to decreased quality of life, limitations in daily functioning, and a higher reliance on healthcare services, resulting in significant economic burdens. …”
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9012
Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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9013
Data Sheet 1_Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study.pdf
Published 2025“…The relationships between the HU value and other data between the vertebral body defect group and the nonvertebral body defect group were compared. We found significant differences in age (70.6 ± 8.4 vs. 63.8 ± 9.5, p < 0.001), sex (male/female) (26/69 vs. 43/61, p < 0.05), BMI (23.8 ± 3.4 vs. 24.8 ± 3.4, p < 0.05), and total spine HUs (84.65 ± 35.49 vs. 124.86 ± 49.59, p < 0.001). …”
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9014
Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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9015
Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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9016
Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf
Published 2025“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”
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9017
Table 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx
Published 2025“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”
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9018
Table 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx
Published 2025“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”
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9019
Image 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf
Published 2025“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”
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9020
Data Sheet 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx
Published 2025“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”