Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics حسب Maximillian K. Osterberg (22514185)

"…A majority of the 2645 quantifiable Cys-containing peptides that show an increase in abundance-corrected Cys reactivity (150) are derived from known Zn-, Fe-, and Fe–S-cluster proteins, revealing a significant decrease in metal occupancy (undermetalation) across the proteome. …"

Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics حسب Maximillian K. Osterberg (22514185)

"…A majority of the 2645 quantifiable Cys-containing peptides that show an increase in abundance-corrected Cys reactivity (150) are derived from known Zn-, Fe-, and Fe–S-cluster proteins, revealing a significant decrease in metal occupancy (undermetalation) across the proteome. …"

Exploring Metalloproteome Remodeling in Calprotectin-Stressed Acinetobacter baumannii Using Chemoproteomics حسب Maximillian K. Osterberg (22514185)

"…A majority of the 2645 quantifiable Cys-containing peptides that show an increase in abundance-corrected Cys reactivity (150) are derived from known Zn-, Fe-, and Fe–S-cluster proteins, revealing a significant decrease in metal occupancy (undermetalation) across the proteome. …"

Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx حسب Xiamei Yan (21014921)

"…Objective<p>To compare the real-world clinical efficacy and safety of interleukin (IL)-17A inhibitors (secukinumab [SEC] and ixekizumab [IXE]) versus the IL-23 inhibitor guselkumab (GUS) in patients with nail psoriasis, with a focus on site-specific biologic therapeutic responses (nail matrix vs. nail bed) in a 24-week prospective observational cohort.…"

Data Sheet 1_The efficacy of ophiopogonanone B in treating the cough in mice infected with Mycoplasma pneumoniae.docx حسب Nan-Nan Liu (12093551)

"…Histological staining using HE and Masson techniques revealed that the lung tissue morphology and structure in the ophiopogonanone B-treated group closely mirrored those observed in the blank group. Subsequent immunohistochemistry and RT-PCR revealed a significant reduction (P < 0.01 or P < 0.05) in the proteins and mRNA expression levels of TRPA1, SP, and CGRP in the lung tissue of mice treated with high and medium doses of ophiopogonanone B.…"

Graded loading creep stress loading level. حسب Dengke Yang (842532)

"…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …"

Schematic diagram of rock samples. حسب Dengke Yang (842532)

"…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …"

Rock mechanics testing machine. حسب Dengke Yang (842532)

"…The results reveal that (1) freeze-thaw cycles exert a significant influence on the rock’s creep behavior, with axial strain, instantaneous strain, and creep strain increasing progressively with the number of freeze-thaw cycles; (2) dual-fractured rock samples with varying fracture angles exhibit distinct differences in creep phenomena, where increased fracture angles result in pronounced increases in instantaneous and creep strains, and higher horizontal stress levels lead to greater strain generation; (3) all rock samples with different pre-existing fractures exhibit rock bridge breakthrough during creep failure, and the variation in fracture angle affects the failure mode; (4) and the long-term strength of the rock varies with changes in fracture angle and freeze-thaw cycle frequency, showing an increasing trend with greater fracture angles but a rapid decrease with increasing freeze-thaw cycles. …"

The variation of creep strain with the number of freeze-thaw cycles. حسب Dengke Yang (842532)

Creep failure morphology and sketch map of intact rock. حسب Dengke Yang (842532)

The variation of instantaneous strain with the number of freeze-thaw cycles. حسب Dengke Yang (842532)

Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf حسب Wei Gong (112494)

"…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …"

Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf حسب Wei Gong (112494)

"…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …"

The variation of creep strain of rock samples with different dip angles of double fissures with stress level. حسب Dengke Yang (842532)

Creep failure mode and sketch map of slow-step fractured rock. حسب Dengke Yang (842532)

Creep failure mode and sketch map of slow-slow fractured rock. حسب Dengke Yang (842532)

Creep curve clusters of rock samples with different fracture dip angles. حسب Dengke Yang (842532)

The variation of instantaneous strain of rock samples with different dip angles of double fissures with stress level. حسب Dengke Yang (842532)

Creep failure mode and sketch map of step-step fractured rock. حسب Dengke Yang (842532)

Long-term creep strength of three kinds of double-fractured rock samples. حسب Dengke Yang (842532)