Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…<p>The PERI-DYS study evaluates patients at very high cardiovascular (CV) risk, including those who receive PCSK9 monoclonal antibodies (PCSK9-mAb) and those who are eligible for PCSK9-mAb but do not receive them.</p> <p>This is a prospective observational registry at 70 sites in Germany, categorising patients by PCSK9-mAb treatment status at baseline. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…Only two serious adverse events were reported (one hyperkalemia and one decreased white blood cell count).</p>Conclusion<p>This real-world study supports the effectiveness and safety of serplulimab-based regimens as a first-line treatment for patients with locally advanced or metastatic esophageal cancer, regardless of their diverse characteristics.…”

Performance following comparative feedback by K. Skylar Powell (15384878)

“…</li></ul><p dir="ltr">Hence, given that there are multiple round observations for each participant, this is a panel dataset.…”

Supplementary Material for: Electrical impedance tomography during the extubation phase in very preterm born infants by figshare admin karger (2628495)

“…The percentage of non-dependent silent spaces decreased of after extubation in successfully extubated patients (p<0.001). …”

Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... by Pengyu Wang (6680312)

“…</p>Methods<p>Diabetic liver injury was induced by a high-fat diet combined with STZ in mice. Biochemical kit detection and H&E staining were used to observe lipid aggregation and oxidative stress in liver tissue. …”

Table 1_The effect of self-compassion versus mindfulness interventions on autonomic responses to stress in generalized anxiety disorders.docx by Xuejun Qi (3842173)

“…We also demonstrated a significant correlation between decreased heart rate response and less negative emotions.…”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. …”

Digitized maps of vascular plant species distributions in Denmark in the early 20th century by Ditte Marie Christiansen (12182972)

“…<p dir="ltr"><b>Historic data are essential for quantifying changes in biodiversity and drivers thereof. A large part of such legacy data are stored undigitized in archives at e.g., natural history museums, and make up significant untapped resources for insights into past biodiversity patterns. …”

Supplementary file 1_Spatiotemporal monitoring in beidagang wetland using Landsat time-series images and Google Earth Engine during 2000–2022.docx by Xinyue Zhang (271120)

“…Therefore, we developed a Decision Tree (DT)-based classification method, incorporating water frequency (WF) and vegetation frequency (VF) calibrated with field observations, to monitor wetland dynamics using Landsat-5/7/8/9 time-series images (2000–2022) and Google Earth Engine (GEE). …”

Data Sheet 1_Boundary currents in the Bransfield Strait: near-surface interbasin water volume and heat exchange.pdf by Marta Veny (20937656)

“…Heat transport analyses reveal significant asymmetries: the Bransfield Current contributes up to 5.44x10¹² W eastward in summer based on a hydrographic climatology constructed from CTD, MEOP, and Argo float measurements (0–100 m depth) and 6.67x10¹¹ W using remotely-sensed sea surface temperature (0–10 m depth). …”

CARE-checklist JOSPT[1].docx by Sanjivani Bangde (19749151)

“…The patient’s pain levels decreased, and functional status improved as indicated by a reduction in score.…”

Table 1_Organic and inorganic fertilizers modulate the response of the soil microbiome to salinity stress.docx by Halima Malal (21570602)

“…Over the long-term, the microbial community evolved into a new pattern under salt stress, favoring the presence of Bacteriodota, a salt-tolerant phylum, while decreasing the relative abundance of Acidobacteriota and Planctomycetota, which are more salt-sensitive. …”

Photomicrograph of the gastric mucosa colored with an anti-caspase-3 antibody. by Rehab F. Taher (20478600)

“…<p>The percentage of caspase-3 positive cells having strong brown coloring is reduced in the omeprazole group (c), while the control ethanol group (d) exhibited increased expression of caspase-3 and a higher percentage of positive cells with powerful brown cytoplasmic and/or nuclear coloring, (d) PM-EtOH (25 mg/kg) group showing decreased expression of caspase-3, along with the presence of moderately stained cells, (e) PM-EtOH (50 mg/kg) group showing decreased percentage of caspase-3 positive cells, (f) PM-EtOH (100 mg/kg) group showing weak caspase-3 expression, via a significant lowering in caspase-3-positively colored cells. …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Data Sheet 1_Inverse associations of the lifestyle critical 9 with cardiorenal syndrome: the mediating role of the dietary inflammatory index.xlsx by Hongman Li (19546419)

“…DII shows a significant positive connection with CRS (p < 0.001), but DII indicates a decreasing trend when LC9 rises (β = −0.65, p < 0.001). …”