Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…<p>In late 2019, the conditional approval process for drugs in China transitioned from a pilot project to a formal program. Our study comprehensively analyzed 103 conditional approvals (CAs) authorized by the National Medical Products Administration (NMPA) from 2020 to 2023, specifically focusing on their characteristics, clinical evidence, and implementation effects. …”

Supplementary Material for: Spontaneous Massive Retroperitoneal Hematoma: A Rare Complication of Anticoagulation after Stenting in Malignant Superior Vena Cava Syndrome by figshare admin karger (2628495)

“…After the procedure, she was on prophylactic low-molecular-weight heparin and developed a large retroperitoneal hematoma with a significant decrease in haemoglobin on day four. …”

Datasheet1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf by Fei He (145896)

“…Significant decreases in trans-coarctation PGs and SBP were observed. …”

Table1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf by Fei He (145896)

“…Significant decreases in trans-coarctation PGs and SBP were observed. …”

Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study by Andrea Loggini (12077927)

“…Elevated cTnI was not significantly associated with sICH (OR:3.75, 95%CI 0.52–27.21, <i>p</i> = 0.19), but was independently associated with increased in-hospital mortality (OR:1.96, 95%CI 1.62–6.20, <i>p</i> = 0.025) and decreased odds of good functional outcome at 30 days (OR:0.40, 95%CI 0.19–0.84, <i>p</i> = 0.016). …”

Data Sheet 1_Endophytic and antagonistic Bacillus amyloliquefaciens 8SE-IF1-derived nanoparticles encumber phytopathogenic oomycetes, fungi, bacteria, and viruses with enhanced gro... by A. Mary Sharmila (21898730)

“…The water-diffusible extract (WDE) of Ba-8SE-IF1 significantly inhibited the mycelial growth of Pythium aphanidermatum (44.6%), Phytophthora nicotianae (60.1%), Fusarium oxysporum f. sp. lycopersici (65.5%), and Colletotrichum gloeosporioides (66.7%) in poisoned food assays; the growth of Ralstonia solanacearum and Xanthomonas campestris in the agar well method (inhibition zones of 20.25 mm and 28.52 mm, respectively); and decreased the symptoms produced by tomato spotted wilt virus (TSWV) in local lesion host (68.3%) and tomato leaf curl New Delhi virus (ToLCNDV) in tomato plants (66.1%). …”

Image 1_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Image 2_Clinical outcomes of an intelligent pressure-controlled disposable ureteroscope for Laser lithotripsy in renal stone surgery: a retrospective matched cohort study.tif by Zhong Lv (4568410)

“…The overall complication rate was significantly lower in the experimental group</p>Conclusions<p>The use of an intelligent pressure-controlled disposable ureteroscope with laser lithotripsy for upper urinary tract surgeries can effectively reduce postoperative inflammation indicators, decrease average hospital stay and renal pelvis pressure, and improve the initial and total stone clearance rates.…”

Data Sheet 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.docx by Chang Liu (35901)

“…Background<p>Sleep deprivation (SD) has been associated with cognitive deficits, mediated by mechanisms such as neuroinflammation and oxidative stress. Acupuncture, a core component of traditional Chinese medicine, has shown promise in mitigating SD-induced cognitive impairment. …”

Supplementary Material for: Impact of early oral feeding on postoperative outcomes after elective colorectal surgery: a systematic review and meta-analysis by Lee S.Y. (4128808)

“…The EOF group demonstrated a decreased time to flatus (mean difference [MD] -0.87; 95% CI -1.00 to -0.74) and shortened hospital stay (MD -0.76; 95% CI -0.89 to -0.6). …”

Data Sheet 1_Perceptions and needs of patients, caregivers and health professionals regarding an oncology community center: a qualitative study.pdf by Inbal Mitnik (21611342)

“…</p>Conclusion<p>The results indicate that the new OCC was perceived as a significant step in developing medical services, however the main concern was a decrease in the level of confidence due to its distance from the hospital. …”

Image 2_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 3_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 1_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 4_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Data Sheet 1_Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study.xlsx by Jiayun Ling (15249289)

“…After 2 weeks of TCZ treatment, median (IQR) serum C3 levels declined from 1.45(1.27-1.75) g/L at baseline to 1.11 (0.97-1.18) g/L (a 23.45% reduction, P = 0.009), and C4 levels decreased from 0.29 (0.21-0.38) g/L to 0.13 (0.09-0.17) g/L (a 55.17% reduction, P = 0.005). …”

<b>Feature-based molecular networking of two Arenga species extracts, appraisal of their anti-inflammatory, analgesic and antidiarrheal activity</b>: Raw data (LC-MS/MS) by Wafaa A. Ahmed (21667440)

“…Also, it decreased the gastrointestinal motility in charcoal meal protocol and a showed an inhibitory effect on gastrointestinal motility with all investigated doses. …”

Effects of Semaglutide and Dapagliflozin on Neuronal Integrity, Apoptosis, and LRP1 Expression in the Hippocampal CA1 Region of T2DM Mice. by Yan Zhu (112437)

“…(D) Quantitative analysis of LRP1 expression shows significantly decreased levels in the T2DM group compared to control (***<i>p</i> < 0.001), while both semaglutide and da<i>p</i>agliflozin treatment significantly restored LRP1 expression compared to the T2DM group (***<i>p</i> < 0.001). …”

Image 1_Effects of ultraviolet radiation as a climate variable on the geographic distribution of Oryza sativa under climate change based on Biomod2.tif by Rulin Wang (4814577)

“…In the future climate scenario, the total suitable habitat area of O. sativa tended to decrease, but the suitable distribution area under the influence of UV was larger than that without UV.…”

Table 1_Efficacy and safety of tranexamic acid in reducing hidden blood loss during unilateral total knee arthroplasty: a retrospective study.xlsx by Luo Liangliang (21466589)

“…The study found that TXA significantly reduced total blood loss by 37.4%, with a notable decrease in hidden blood loss (p < 0.05). …”