Table 1_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.doc by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Image 2_A WRKY transcription factor, SlWRKY75, positively regulates tomato (Solanum lycopersicum L.) resistance to Ralstonia solanacearum.tif by Na Chen (153323)

“…In this study, subcellular localization revealed that SlWRKY75 is located in the nucleus, while the transcriptional activation assay indicated that SlWRKY75 acts as a transcriptional activator. To investigate the functional role of SlWRKY75, we generated overexpression transgenic lines. …”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…<p>Sleep disturbances are common in Alzheimer’s disease (AD) and AD-related dementia (ADRD). We performed a sleep study on Tg-SwDI mice, a cerebral amyloid angiopathy (CAA) model, and age-matched wild-type (WT) control mice. …”

Data_Sheet_1_Exercising educational equity using California’s physical fitness data: a call for more school physical fitness programs, data, and research.docx by Da’Shay Templeton (19802262)

“…The lack of safe and affordable options for physical activity coupled with the significant decrease in physical activity rates among most American children underscores the need for programs, data, and research on physical fitness in schools, where children spend a significant amount of their time. …”

The upper plots show the changes in ZMK for summer and autumn. by Peyman Karami (5909264)

“…<p>Red indicates an increasing trend and green indicates a decreasing trend in fire density. The lower plots show significant increasing and decreasing trends for different biomes in Iran.…”

Table 2_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Table 3_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Image 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.jpg by Roberta Belli (6939221)

“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”

Data Sheet 1_The sigma factor σ54 (rpoN) functions as a global regulator of antibiotic resistance, motility, metabolism, and virulence in Clostridioides difficile.docx by Ying Yang (24175)

“…Additionally, rpoN deletion led to a decrease in glucose metabolic rate, which we attribute to the downregulation of glycolytic enzymes. …”

Potential of Fenfuro^®, a novel, standardized <i>Trigonella foenum-graecum</i> (Fenugreek) seed extract, in ameliorating glycation-mediated amyloidogenesis by Sreemoyee Saha (20391298)

“…It was determined that these significant spectral changes were due to a combined effect of the protein as well as non-protein part of the extract and not attributable to any single bioactive component. …”

Adverse event list. by Stefan Halbherr (21353882)

“…</p><p>Methods and findings</p><p>We prospectively enrolled 12 patients with PD into a single-center, open-label phase I trial to assess the safety and tolerability of weekly infusions with TLN. …”

Patient characteristics. by Stefan Halbherr (21353882)

“…</p><p>Methods and findings</p><p>We prospectively enrolled 12 patients with PD into a single-center, open-label phase I trial to assess the safety and tolerability of weekly infusions with TLN. …”

Supplementary file 1_Characteristics, clinical evidence and implementation effects of conditional approvals for drugs in China, a pooled analysis from 2020 to 2023.docx by Li Yang (6520)

“…<p>In late 2019, the conditional approval process for drugs in China transitioned from a pilot project to a formal program. Our study comprehensively analyzed 103 conditional approvals (CAs) authorized by the National Medical Products Administration (NMPA) from 2020 to 2023, specifically focusing on their characteristics, clinical evidence, and implementation effects. …”

Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx by Dan-Ni Yang (17642947)

“…This study aimed to investigate the influence of age and sex on the accuracy of CEA for differentiating MPE and benign pleural effusion (BPE).</p>Methods<p>We enrolled participants from a prospective cohort (SIMPLE) and a retrospective cohort (BUFF). …”

Supplementary file 1_Effects of nitrogen addition on SOC in alpine grasslands of the Qinghai-Tibetan Plateau and adjacent mountain regions: a meta-analysis.docx by Yanhui Ye (22775894)

“…However, long-term additions promote C loss via soil acidification and a critical shift in the microbial community, notably a decreased fungal-to-bacterial ratio. …”

Supplementary file 1_Wearable-derived heart rate variability and sleep monitoring as predictors of mood episodes in bipolar disorder: a case report.jpg by Aiko Eto (22769225)

“…Background<p>Bipolar disorder is a chronic psychiatric condition characterized by alternating episodes of mania and depression, and the prediction and management of mood episodes remain significant clinical challenges. …”

Table 1_The nonlinear relationship between estimated glomerular filtration rate and cardiovascular disease in US adults: a cross-sectional study from NHANES 2007–2018.docx by Ce Zhou (2257300)

“…</p>Results<p>The study revealed a significant non-linear inverse association between eGFR and CVD risk, with a threshold effect observed at 99.3 ml/min/1.73 m². …”

Table 3_Associations between vitamin K and systemic immune and inflammation biomarkers: a population-based study from the NHANES (2007–2020).docx by Wenjiao Luo (1805428)

“…When the level of vitamin K intake was less than 237.7 mcg/d, RAR showed a significant decreasing trend with the increase of vitamin K. …”

Image 1_Associations between vitamin K and systemic immune and inflammation biomarkers: a population-based study from the NHANES (2007–2020).pdf by Wenjiao Luo (1805428)

“…When the level of vitamin K intake was less than 237.7 mcg/d, RAR showed a significant decreasing trend with the increase of vitamin K. …”