Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx حسب Maria Cristina Ceccarelli (19233688)

"…The co-treatment with PDNPs effectively mitigated these effects by reducing oxidative stress, suppressing the upregulation of M1 markers, and decreasing cytokine release, thereby preventing the shift toward a pro-inflammatory state. …"

Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds حسب Wen Gu (129075)

"…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …"

Table 1_Optimization of drying parameters and texture properties of winter jujube slices by radio frequency combined with hot air.xlsx حسب Yang Li (7082)

"…Vitamin C (VC) content, red and green value (a*), and drying rate (DR) were used as quality indexes, and the changing trend of texture properties was analyzed. …"

Table 1_Uniaxial tensile material properties of adult Chinese dura mater: investigating the influence of age, sex, and anatomical site.docx حسب Jinming Wang (191356)

"…</p>Results<p>indicated significant age-related degradation: E_C, σ_Tf, ε_Tf; and MaxForce significantly decreased with age (median E_C declined from 28.0 MPa in young adults to 15.3 MPa in the elderly, P < 0.05; median ε_Tf from 0.215 to 0.156, P < 0.05), while E_E showed no significant age correlation (P = 0.10). …"

Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC حسب Xikai Luo (21520875)

"…RUNX1 promoter SNP rs2071029T had a decreased risk of severe CIN compared with rs2071029C. …"

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models... حسب Shreshta Jain (12274885)

"…</p>Results<p>Decanoic acid significantly improved learning and memory performance, enhanced antioxidant enzyme activity (superoxide dismutase, reduced glutathione, catalase), promoted autophagy by inhibiting mTOR, reduced cellular senescence (β-galactosidase-positive cells), and decreased amyloid-β toxicity. …"

Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg حسب Shenglan He (7641308)

"…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …"

Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes حسب Motoshi Kozakai (22435636)

"…</p> <p>MSC-ex might be a novel alternative therapeutic tool for treatment of existing AAs.…"

Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx حسب Lai Yuan (20136422)

"…However, it is still unknown whether DBM has a beneficial effect on cognitive deficits and depression.…"

Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif حسب Jingyi Zhang (741111)

"…</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …"

Data Sheet 1_Impact of iron ore mining activities on the rhizosphere fungal communities of Musa basjoo, Apegdalus persica, and Triticum aestivum L..pdf حسب Caijing Wan (20699261)

"…The results revealed that, due to iron ore mining, the pH value of the soil in the mining area generally exhibited weak acidity, and the Fe and TP contents increased significantly (P < 0.05). Notably, iron ore mining reduced fungal diversity in the rhizosphere, and only the wheat group presented a significant reduction in fungal diversity (P < 0.05). …"

Data Sheet 1_Neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; systemic immune-inflammatory Index: inflammatory indicators of cognitive impairment in schizophrenia pati... حسب Ke Chen (73307)

"…Higher NLR, PLR, and SII were substantially related to an increased risk of CI, but higher lymphocytes were associated with a decreased risk of CI.</p>Conclusion<p>NLR, PLR, and SII may be serum inflammatory markers of CI in schizophrenia, and lymphocytes may be protective variables for cognitive function in schizophrenia.…"

Data Sheet 1_Nitrogen effects and genotypic variation in Cd absorption, translocation, and chemical forms in wheat.docx حسب Xiaoli Wu (58959)

"…Moreover, increasing N fertilization significantly decreased soil pH, increased soil Cd exchange capacity and soil Cd bioavailability, resulting in increased Cd accumulation in plants, Chuanmai88 promoted the activation of the Cd migration in the soil.…"

Table 1_Optimization of ultrasonic-assisted extraction of total flavonoids from Zanthoxylum bungeanum residue by response surface methodology and evaluation of its algicidal proper... حسب Jie Cheng (294193)

"…Meanwhile, treatment with Z. bungeanum residue extract at doses of 40.0 mg/L significantly decreased the Fv/Fm and PIabs values of T. obliquus by 24.36 and 88.87% at 50 h, respectively. …"

Table 1_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.xlsx حسب Chenchao Zou (22768010)

"…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …"