Image 1_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 3_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Table 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Image 4_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 7_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 9_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 8_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Image 2_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Image 5_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Data Sheet 1_Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study.xlsx by Jiayun Ling (15249289)

“…Notably, C3 remained significantly correlated at week 48 (r = 0.513, P = 0.025). …”

Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx by Ke He (331344)

“…The centroid ratio slightly decreased with increasing DBH, indicating that larger trees tend to have more ovate leaves than elliptical leaves. …”

Suppl. Figure 1, García-Ortuño, et al. by NORMA A. Bobadilla (22642043)

“…After delivery, maternal body weight decreased, returned to pre-gestational values and remained stable throughout lactation, with no differences observed among the four groups of dams (Suppl. …”

Supplementary Data for article '<b>Long-term biochar amendment alters microbial necromass carbon accumulation in topsoil and subsoil of two contrasting croplands: Alfisol and Ultis... by Zhiwei Liu (17302867)

“…Compared to the biochar-free control, biochar amendment significantly increased total necromass C (TNC) by 45.9% in the topsoil of Ultisol but decreased it by 9.9% in Alfisol. …”

Data Sheet 1_Perilipin 5 alleviates ferroptosis of cardiomyocytes by targeting USP10-p53-TfR proteasome-dependent degradation.docx by Jianqiao Zhao (14519036)

“…</p>Methods<p>H9c2 cells were treated with H₂O₂ and Erastin, while the rat model of MI was established by ligating the left anterior descending coronary artery.</p>Results<p>We found that after MI, cardiac subcellular iron levels increased and the expression of PLIN5 decreased. …”

Data Sheet 1_Global, regional, and national trends and burden of hypertensive disorders in pregnancy among women of childbearing age from 1990 to 2021.pdf by Zhongyun Tang (21287855)

“…</p>Conclusion<p>Over the past 32 years, HDP prevalence cases and incidence cases have risen globally, but death cases and DALYs cases have significantly decreased, particularly in low SDI regions and the 25–29 age group. …”

Table 1_GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells.xlsx by Fumiya Ito (14833366)

“…However, resistance to EGFR inhibitors, such as erlotinib, presents a significant challenge in treating lung cancer. In this study, we established an EGFR-independent, erlotinib-resistant (ER) phenotype in lung cancer A549 cells by exposing them to erlotinib for an extended period. …”

Data Sheet 2_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx by Yang Yu (4292)

“…TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …”

Table 1_Puf4 -mediated oxidative stress virulence attenuation in Cryptococcus neoformans.docx by Chenhao Suo (7022351)

“…</p>Methods<p>In this study, we systematically investigated the role of Puf4 in the metabolism and virulence of C. neoformans using RNA sequencing (RNA-seq), biochemical analysis, and in vivo animal experiments.…”