Supplemental Figures by Danielle A. Jeffrey (21187329)

“…FXR1 has seven isoforms, including isoforms mostly expressed in skeletal and cardiac tissue, and play a significant role in heart development and function. …”

Effects of Semaglutide and Dapagliflozin on Neuronal Integrity, Apoptosis, and LRP1 Expression in the Hippocampal CA1 Region of T2DM Mice. by Yan Zhu (112437)

“…(D) Quantitative analysis of LRP1 expression shows significantly decreased levels in the T2DM group compared to control (***<i>p</i> < 0.001), while both semaglutide and da<i>p</i>agliflozin treatment significantly restored LRP1 expression compared to the T2DM group (***<i>p</i> < 0.001). …”

Table 1_Disc degeneration influences the strain magnitude and stress distribution within the adjacent trabecular bone.docx by Kay A. Raftery (17080234)

Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx by Yutong Wu (3130584)

“…</p>Methods<p>We compiled a real-world safety dataset of nivolumab from the FDA Adverse Event Reporting System (FAERS) database, encompassing reports from Q4–2014 through Q2 2024. …”

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

S3 File - by Zi-Yun Yi (19859589)

“…In contrast, MII oocytes in the TSD group showed a decrease in the mtDNA copy number and a lower Δψm compared with the controls. …”

S2 File - by Zi-Yun Yi (19859589)

“…In contrast, MII oocytes in the TSD group showed a decrease in the mtDNA copy number and a lower Δψm compared with the controls. …”

Image_2_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…A common single nucleotide polymorphism (SNP) in the pro-domain of the human BDNF gene that leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) significantly decreases activity-dependent BDNF release without affecting basal BDNF secretion. …”

Image_1_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…A common single nucleotide polymorphism (SNP) in the pro-domain of the human BDNF gene that leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) significantly decreases activity-dependent BDNF release without affecting basal BDNF secretion. …”

Table 1_Factors affecting health-seeking behavior in sports climbers in Metro Manila: a cross-sectional study.docx by Danyelle Jay T. Cruz (20772668)

“…Among the injury factors studied, the location of pain at the hip/pelvis and knee was found to be significant (p < 0.05).</p>Discussion<p>Climbers in Metro Manila have a decreased tendency to engage in health-seeking behavior. …”

Data Sheet 1_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 6_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 3_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 2_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 4_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Data Sheet 5_Efficacy and safety of different medications compared for the treatment of postherpetic neuralgia: a network meta-analysis.pdf by Zhen Guo (68566)

“…The secondary outcomes showed a significant effect of hydromorphone in improving sleep quality (MD = −3.8, 95% CI: [−23.0, −15.0]) and decreasing pain questionnaire scores (MD = −13.0, 95% CI: [−28.0, 2.1]). …”

Table 1_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…All levels of PA were significantly associated with a decreased risk of cardiovascular death with HRs ranging from 0.577 to 0.938 (P < 0.01). …”

Table 2_Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.pdf by Yanwen Chen (460790)

“…All levels of PA were significantly associated with a decreased risk of cardiovascular death with HRs ranging from 0.577 to 0.938 (P < 0.01). …”

Table 1_Gut microbiota alterations and systemic inflammation in community-acquired pneumonia: a prospective gut-lung axis study.docx by Xue-Qin Yang (3494345)

“…The abundance of short-chain fatty acid-producing genera in CAP patients decreased significantly, such as Blautia and Agathobacter. …”

List of primers used in quantitative RT-PCR. by Tarek A. Essa (22430744)

“…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …”