Image 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.tif by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.docx by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_The impact of diagnosis-related group-based medical insurance payment model on the prognosis and nursing care of patients undergoing composite trabeculectomy: a retrospecti... by Yu Wang (12152)

“…Similarly, when comparing follow-up indicators after more than 6 months post-surgery between the two groups, visual acuity (p > 0.05), intraocular pressure (p > 0.05), and field of view (p > 0.05) were not significantly different from baseline.</p>Conclusion<p>This study represents the first empirical validation demonstrating that the implementation of the Diagnosis-Related Groups (DRG)-based medical insurance reform significantly reduced the mean length of hospital stay for patients undergoing compound trabeculectomy (from 8 days to 5 days). …”

Data Sheet 2_An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults.pdf by Luisa Knopf (22518134)

“…The trajectories in cortisol levels throughout the session, especially around the memory task, differed by age: While there was a decrease in cortisol levels for younger adults from before to after the memory task, we did not observe such a decrease in older participants. …”

Data Sheet 1_An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults.pdf by Luisa Knopf (22518134)

“…The trajectories in cortisol levels throughout the session, especially around the memory task, differed by age: While there was a decrease in cortisol levels for younger adults from before to after the memory task, we did not observe such a decrease in older participants. …”

Table 1_Assessing and projecting the global impacts of Alzheimer’s disease.docx by Nanlong Zhang (20563511)

“…</p>Conclusion<p>From 1990 to 2030, global burden of AD is projected to decrease, with significant gender and regional disparities. …”

Table 1_Revising cancer incidence in a Central European country: a Hungarian nationwide study between 2011–2019 based on a health insurance fund database.xlsx by Zoltán Kiss (5570003)

“…All-site cancer incidence showed a mean annual decrease of 1.9% (95% CI: 2.4%-1.4%) in men and 1.0% (95% CI:1.42%-0.66%) in women, parallel to mortality trends (-1.6% in males and -0.6% in females; ESP 2013). …”

Table 1_Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression.xlsx by Fangmin Zhong (17415318)

“…Patients with high autophagy scores had a greater proportion of regulatory T-cell infiltration and greater cytokine–cytokine receptor interaction signaling pathway activity, while patients with low autophagy scores had greater γδT cell infiltration and PD-1 expression. …”

Multimorbidity and health related quality of life in midlife – a longitudinal study from Northern Finland Birth Cohort 1966 by Oili Junttila (21337262)

“…Furthermore, the more diseases the patient had at the age of 31, the more mean 15D-Scores decreased when having more new emerging diseases at the age of 46.…”

Betti curves of CD4(+) T cells, B220(+) DN T cells and megakaryocytes populations in the murine spleen tissue. by Maria Torras-Pérez (22439376)

“…I, J, K, L: same plots for megakaryocytes, but for the case of Betti-0 curves, which count the proportion of clusters which are alive at a given parameter value. We observe a very sharp decrease in the disease curves at small values, which is due to the presence of clusters in the cell population cells.…”

Data_Sheet_1_Synergistic co-evolution of rhizosphere bacteria in response to acidification amelioration strategies: impacts on the alleviation of tobacco wilt and underlying mechan... by Zhang Bian-hong (19768686)

“…The key factors controlling wilt were identified through random forest regression analysis as an increase in soil pH and exchangeable bases, along with a decrease in exchangeable acidity. However, lime treatment alone led to an increase in soil bulk density and a decrease in available nutrients, whereas both biochar and lime-biochar treatments significantly improved these parameters (p < 0.05). …”

DataSheet1_RETRACTED: MiRNA-200b Regulates RMP7-Induced Increases in Blood-Tumor Barrier Permeability by Targeting RhoA and ROCKII.XLS by Teng Ma (109475)

“…Microarray analysis revealed 34 significantly deregulated miRNAs including miR-200b in the BTB as induced by RMP7 and 8 significantly up-regulated miRNAs in the BTB by RMP7. …”

Supplementary file 1_Soluble suppression of tumorigenicity-2 changes during cardiotoxic cancer treatment: a systematic review and meta-analysis.docx by Luca Fazzini (22599380)

“…Using random-effects models, mean differences (MD), and standardized MD (SMD), we analyzed (i) ST2 longitudinal changes, (ii) the association between ST2 and cardiotoxicity [defined through left ventricular ejection fraction (LVEF)] providing pooled estimates of correlations, and (iii) the SMD variations among biomarkers.…”

Image 2_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg by Joshua G. Macopson-Jones (20311497)

“…Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…”

Image 1_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg by Joshua G. Macopson-Jones (20311497)

“…Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…”

Image 3_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg by Joshua G. Macopson-Jones (20311497)

“…Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…”

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

Data Sheet 1_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”

DataSheet1_Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.docx by Chaoli Chen (20359785)

“…The difference was also significant after 6 months (38.06% in the PGxT group vs. 24.84% in the TAU group; p < 0.001). …”

Data Sheet 1_Aberrant white matter and subcortical gray matter functional network connectivity associated with static and dynamic characteristics in subjects with temporal lobe epi... by Sukesh Kumar Das (21359084)

“…The study also demonstrates that the static functional connectivity strength (FCS) of the left ILF decreased significantly in subjects with TLE. However, the dynamic FCS of the splenium and brain stem were altered significantly in TLE, implying that the total dynamic connections of this network with all other networks experienced greater changes. …”