S1 Graphical abstract - by Hai Nguyen Ngoc Dang (19200560)

“…Furthermore, the median aortic compliance (AC, 10^-2mm/mmHg) and aortic distensibility (AD, 10^-3mmHg^-1) in individuals with T2DM were 4.07 (2.28–7.44) and 3.08 (1.57–5.26), respectively, lower than those in the control group, with median values of 6.40 (3.08–10.75) and 5.33 (2.80–9.79). A longer diabetes duration was linked to a greater ASI (r = 0.43, p < 0.05), while the AS decreased (r = -0.37, p < 0.05).…”

Data Sheet 1_Genetic variation in RYR1 is associated with heart failure progression and mortality in a diverse patient population.docx by Leonardo A. Guerra (20762270)

“…Based on eQTL data, these SNPs were associated with decreased RYR1 expression in vascular tissue. Two missense variants, in linkage disequilibrium with rs2915950 (rs2915952 and rs2071089) were significantly associated with decreased mortality risk (P = 0.03) and decreased risk of atrial fibrillation/flutter (OR: 0.66, 95% CI: 0.44–0.96; P = 0.03 and OR: 0.67, 95% CI: 0.45–0.98; P = 0.04, respectively). …”

Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study by Andrea Loggini (12077927)

“…</p> <p>We conducted a multicenter retrospective cohort study of AIS patients treated with thrombolytics at Southern Illinois Healthcare and the University of Oklahoma (2017–2024). …”

Rescue of <i>pbp1</i>-KD phenotypes using CRISPRi trans-complementation. by Gregory A. Harrison (16639446)

“…Dots indicate individual cells, and the larger, outlined symbols represent the mean cell length from each replicate. The mean and standard deviation were calculated across replicates; statistical significance was determined by a one-way ANOVA with Tukey’s multiple comparisons test. ns, not significant; **** p < 0.0001.…”

Data Sheet 1_Morning spot urinary cortisol-to-creatinine ratio: a novel screening tool for assessing excess cortisol secretion.docx by Yingning Liu (22643762)

“…The negative predictive value (NPV) of morning spot UCCR was 83.5% for cortisol >1.8 µg/dL and 96.8% for >5.0 µg/dL post-1mg DST. A significant reduction in ROC AUC was observed in males, with a borderline decrease noted in patients with diabetes.…”

Table 1_Assessment the relationship between health anxiety and iranian nurses’ quality of life: a cross-sectional study.docx by Zahra Amoozadeh (20944724)

“…</p>Conclusion<p>This study showed that there is a significant relationship between health anxiety and different dimensions of quality of life, so that the quality of life of nurses decreases with the increase of health anxiety.…”

Trimester-specific thyroid function markers and gestational diabetes risk: evidence from a tertile-based cohort of euthyroid pregnancies by Erkan Sağlam (21764816)

“…TSH levels increased, while fT3 and fT4 levels decreased significantly across trimesters (<i>p</i> < 0.001). …”

Sample collection methods and preliminary analysis of sequencing data. by Zhen Wu (358187)

Fig 6 - by Joon Young Park (15256702)

“…The binding intensity of RpoD upstream of <i>ptsG</i> and <i>ptsHI</i> significantly decreases in response to heat shock. (C) Heat map showing sigma factor binding and expression change for carbon metabolism genes in response to heat shock. …”

Data Sheet 1_Efficacy of antioxidant intervention and exercise intervention for lipid peroxidation in dialysis patients: a meta-analysis.zip by Mengyuan Yu (3568580)

“…Curcumin supplementation significantly reduced Ox-LDL levels (p = 0.03). Exercise intervention decreased MDA levels (p < 0.0001). …”

Table 1_Effects of different reduction patterns on stress distribution in patients with intertrochanteric fractures with intramedullary nail fixation: a finite element analysis.xls... by Jiajing Zhu (5117738)

“…</p>Results<p>As the head–neck fragment moved forward, the von Mises stress at the fracture surface, the proximal intersection point of the intramedullary nail, and the distal intersection point gradually decreased. This resulted in reduced fracture displacement, a significant decrease in trabecular bone volume, and a slight increase in the risk of screw cut-out. …”

Data_Sheet_1_Discovering a novel glycosyltransferase gene CmUGT1 enhances main metabolites production of Cordyceps militaris.docx by Rong-an He (19925664)

“…However, C. militaris strains are highly susceptible to irreversible degradation in agricultural production, which is often manifested as a prolonged color change period and a significant decrease in the production of secondary metabolites. …”

Figure 4 from OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility by Hanieh Taheri (20944284)

“…<p>OATP1B deficiency results in elevated AI plasma exposure and decreased liver accumulation. <b>A,</b> Pharmacokinetic profile of letrozole after a single oral dose of 10 mg/kg in wild-type and Oatp1a/1b^(−/−) mice. …”

Glial 5-HT_2a receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…The Or42a OSN innervation volume with glial <i>5-HT</i>_<i>2A</i><i>R</i> OE is very significantly decreased in comparison to the control EB condition (<i>p</i> = 4.64 × 10⁻¹⁰). …”

Reconstruction of RpoS regulon under both control and heat shock conditions. by Joon Young Park (15256702)

“…<p>(A) The scatter plot illustrates the relationships between intensity and transcript expression levels related to RpoD and RpoS binding in response to heat shock. …”

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx by Aierpati Moheteer (21522284)

“…Therapeutic evaluation in a DSP nanoparticles-treated mouse liver hydatid model revealed that the DSP nanoparticles-H group significantly reduced liver, spleen, and vesicle weights compared to both control and albendazole (ABZ)-treated groups (P <0.05). …”

Data Sheet 1_Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis.pdf by Hao Liu (12832)

“…The remaining interventions indicated a trend toward reducing SIC incidence; however, this was not statistically significant.…”

Data Sheet 1_Association between interleukin gene polymorphisms and the risk of pneumoconiosis: a systematic review and meta-analysis.zip by Lu Liu (171341)

“…Overall, there was a significant association between IL-1RA +2018 and IL-6 -634 with the risk of pneumoconiosis. …”

Table 1_Impact of repeated in-vitro bacterial culture on virulence and antibiotic resistance characteristics: a study of Gram-positive and Gram-negative fish pathogens.docx by Angana Bag (21398267)

“…The fish pathogenic bacterial isolates, namely Lactococcus lactis, Enterococcus gallinarum, Proteus penneri, and Escherichia coli, underwent 56 consecutive subcultures in tryptic soy broth and were evaluated for virulence, antimicrobial susceptibility, and AMR gene expression. The results revealed a significant decrease in the virulence of Gram-positive pathogens. …”

Microemulsion for stimulating wells with high gas and water cut by Baghir A. Suleimanov (20460195)

“…It has been found that the treatment of the bottomhole zone with the developed microemulsion leads to a significant reduction in the size of gas bubbles due to a decrease in interfacial tension, which facilitates their removal from the bottomhole zone and increases hydraulic diffusivity of the porous medium for oil approximately five times. …”