The impact of chronic pain on the quality of life of patients attending soshanguve community health centre (CHC), Tshwane district, South Africa by Thanyani Pandelani (8218809)

“…<p dir="ltr">Background: Chronic pain poses a considerable challenge to individuals' well-being, leading to decreased quality of life, limitations in daily functioning, and a higher reliance on healthcare services, resulting in significant economic burdens. …”

Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff by Haoming Shen (3816988)

“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”

Data Sheet 1_Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study.pdf by Song Hao (5700608)

“…The relationships between the HU value and other data between the vertebral body defect group and the nonvertebral body defect group were compared. We found significant differences in age (70.6 ± 8.4 vs. 63.8 ± 9.5, p < 0.001), sex (male/female) (26/69 vs. 43/61, p < 0.05), BMI (23.8 ± 3.4 vs. 24.8 ± 3.4, p < 0.05), and total spine HUs (84.65 ± 35.49 vs. 124.86 ± 49.59, p < 0.001). …”

Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff by Haoming Shen (3816988)

“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”

Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip by Haoming Shen (3816988)

“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”

Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf by Kai Sun (140584)

“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”

Table 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”

Table 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”

Image 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf by Kai Sun (140584)

“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”

Data Sheet 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…</p>Methods and results<p>Utilizing a comprehensive pan-cancer analysis with datasets from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), ArrayExpress database and the International Cancer Genome Consortium (ICGC), we evaluated the prognostic significance of CHMP4A, its clinical implications, associated signaling pathways, DNA methylation status, immune cell infiltration, and response to chemotherapy. …”

Data Sheet 1_Quantifying the temporal trends of the combined effect of temperature and relative humidity on hand, foot, and mouth disease in Yunnan, China.pdf by Zhaohan Wang (9333969)

“…Background<p>Hand, foot, and mouth disease (HFMD) poses a significant risk to children. While most studies focus on the individual effects of temperature or relative humidity, the combined effect of these factors and their temporal variations remain unclear. …”

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel by Satoshi Kaneda (571209)

“…Statistical calculations were performed in R version 4.2.2 (R Development Core Team, 2022), and the significance of the explanatory variable was assessed with F-tests using package car. …”

Data Sheet 3_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.docx by Li Cui (37567)

“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Table_1_Oxidative stress and inflammation mediate the association between elevated oxidative balance scores and improved sleep quality: evidence from NHANES.docx by Qu Zhang (486455)

“…Sensitivity analyses revealed a significant association between OBS and sleep disorder (p < 0.001).…”

Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…Despite advances in cardiac care and infection control, the global burden, temporal trends, and regional disparities of pediatric IE remain poorly characterized.</p>Methods<p>We conducted a comprehensive analysis of pediatric IE burden among children aged 5–14 years using the Global Burden of Disease (GBD) 2021 dataset. …”

Image 1_The advanced lung cancer inflammation index as a predictor of kidney stone risk in men: a cross-sectional analysis.tif by Yan Zhou (6523)

“…Background<p>Kidney stone incidence and recurrence are increasing, which poses significant health problems. The Advanced Lung Cancer Inflammation Index (ALI) combines body mass index (BMI), albumin, and neutrophil-to-lymphocyte ratio (NLR). …”

Table 1_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”

Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Image 4_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Systemic iron overload, which leads to serious complications and affects both patients’ quality of life and overall survival, is a common clinical challenge in patients with acute myeloid leukemia (AML). We previously elucidated the direct effects of iron overload on AML cells. …”

Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx by Nan Jiang (21252)

“…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …”