Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation by Wang Ka LEE (20876477)

“…Flow cytometric analysis confirmed increased HSC populations and progenitor activation for megakaryocyte, erythrocyte, and lymphocyte lineages. The CFU assay showed a significant increase in BFU-E and CFU-G, but a decrease in CFU-GM in FL-HSCs from the H-PFOS group, indicating altered differentiation potential. …”

Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation by Wang Ka LEE (20876477)

“…Flow cytometric analysis confirmed increased HSC populations and progenitor activation for megakaryocyte, erythrocyte, and lymphocyte lineages. The CFU assay showed a significant increase in BFU-E and CFU-G, but a decrease in CFU-GM in FL-HSCs from the H-PFOS group, indicating altered differentiation potential. …”

Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation by Wang Ka LEE (20876477)

“…Flow cytometric analysis confirmed increased HSC populations and progenitor activation for megakaryocyte, erythrocyte, and lymphocyte lineages. The CFU assay showed a significant increase in BFU-E and CFU-G, but a decrease in CFU-GM in FL-HSCs from the H-PFOS group, indicating altered differentiation potential. …”

Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation by Wang Ka LEE (20876477)

“…Flow cytometric analysis confirmed increased HSC populations and progenitor activation for megakaryocyte, erythrocyte, and lymphocyte lineages. The CFU assay showed a significant increase in BFU-E and CFU-G, but a decrease in CFU-GM in FL-HSCs from the H-PFOS group, indicating altered differentiation potential. …”

Impact of PFOS Exposure on Murine Fetal Hematopoietic Stem Cells, Associated with Intrauterine Metabolic Perturbation by Wang Ka LEE (20876477)

“…Flow cytometric analysis confirmed increased HSC populations and progenitor activation for megakaryocyte, erythrocyte, and lymphocyte lineages. The CFU assay showed a significant increase in BFU-E and CFU-G, but a decrease in CFU-GM in FL-HSCs from the H-PFOS group, indicating altered differentiation potential. …”

Complementary conditioning measures across the clinical study groups. by Gabriela Ribeiro (4748373)

“…Post hoc tests showed significant decreases for the surgical group (<i>P</i> = 0.05), while in the remaining groups, results did not reach significance (Healthy, <i>P</i> = 0.4; Obese, <i>P</i> = 0.1). …”

Complementary conditioning measures in healthy subjects. by Gabriela Ribeiro (4748373)

“…<b>(I) Novelty</b> ratings significantly decreased from pre to post-conditioning (F_(1,51) = 10.2, <i>P</i> = 0.002; post hoc CS^-, <i>P</i> = 0.0001; post hoc CS⁺, <i>P</i> = 0.01) but similarly for both stimuli (F_{(1, 51)} = 0.17, <i>P</i> = 0.7; Interaction: F_{(1, 51)} = 1.1, <i>P</i> = 0.3). …”

Participant interview topics. by Lex D. de Jong (22138778)

“…</p><p>Conclusion</p><p>Using a valgus brace decreased knee pain intensity during walking activities. …”

The participants’ baseline characteristics. by Lex D. de Jong (22138778)

“…</p><p>Conclusion</p><p>Using a valgus brace decreased knee pain intensity during walking activities. …”

General data comparison. by Haifeng Chang (386047)

“…</p><p>Conclusion</p><p>The COVID-19 pandemic has impacted trauma patients admitted through the emergency department, with increases in the proportion of male and younger patients, surgical cases, and a decrease in mortality rates during the pandemic.…”

The epidemic period group. by Haifeng Chang (386047)

“…</p><p>Conclusion</p><p>The COVID-19 pandemic has impacted trauma patients admitted through the emergency department, with increases in the proportion of male and younger patients, surgical cases, and a decrease in mortality rates during the pandemic.…”

Original data. by Haifeng Chang (386047)

“…</p><p>Conclusion</p><p>The COVID-19 pandemic has impacted trauma patients admitted through the emergency department, with increases in the proportion of male and younger patients, surgical cases, and a decrease in mortality rates during the pandemic.…”

Post-epidemic group. by Haifeng Chang (386047)

“…</p><p>Conclusion</p><p>The COVID-19 pandemic has impacted trauma patients admitted through the emergency department, with increases in the proportion of male and younger patients, surgical cases, and a decrease in mortality rates during the pandemic.…”

Comparison of admissions by department. by Haifeng Chang (386047)

“…</p><p>Conclusion</p><p>The COVID-19 pandemic has impacted trauma patients admitted through the emergency department, with increases in the proportion of male and younger patients, surgical cases, and a decrease in mortality rates during the pandemic.…”

Source data for Fig 2. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for lung metabolomics. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 5. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 1. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Flow cytometry gating strategy for MDSC. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 3. by Qi Xu (134661)

“…Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”