The enriched GO terms of the 19 DECAGs. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Primers of the tested genes. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Summary of patient demographic characteristics. by Jing Wang (6206297)

“…Subsequently, in the single-cell analysis of AD peripheral blood, all hub-genes except SOD1 were found to be up-regulated in B cells, NK cells, and CD4+ T cells, possibly acting on the MIF pathway. Finally, we discovered that the levels of <i>PDK1</i> expression in AD patients were remarkably upregulated, while <i>FDX1</i> and <i>GLS</i> were significantly decreased using qPCR.…”

Supplementary Material for: The Association Between Tumor Necrosis Factor-Alpha Inhibitor Use and Dementia Risk in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-... by figshare admin karger (2628495)

“…Also, the subgroup analyses indicated that TNFi use was associated with a decreased dementia risk in older adult patients with a mean age of ≥65 years at enrollment (HR = 0.86, 95% CI 0.80-0.92) and in TNFi new users (HR = 0.86, 95% CI 0.80-0.92). …”

Table 1_COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023).xls by Xiaoqiang Li (612879)

“…The MIC values for vancomycin in MRSA strains remained stable over time, whereas a decreasing susceptibility trend to vancomycin in MSSA strains and linezolid MIC shifts were not observed. …”

Supplementary file 1_Changes of potential shorty-chain fatty acids producing bacteria in the gut of patients with spinal cord injury: a systematic review and meta-analysis.zip by Zaowei Zhong (20796020)

“…<p>Gut bacteria that potential produce short-chain fatty acids (SCFAs) influences the recovery of motor function in the host in patients with spinal cord injury (SCI). We aimed to conduct a review and meta-analysis of the literature on gut microbiota in SCI patients. …”

Supplementary file 1_Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study.docx by Zhiyu Qiao (12514712)

“…For every 10 mL/min/1.73 m² increase in eGFR_diff, the incidence of various diseases decreased by approximately 10–19%.</p>Conclusion<p>eGFR_diff is significantly associated with increased risks of mortality, CVD incidence, and multiple CVD-related conditions. …”

Data_Sheet_1_Evaluating a computer-based body exposure paradigm for the treatment of body image disturbance in adolescent Anorexia Nervosa: effects on the attentional bias and emot... by Lena Sasse (20434616)

“…</p>Conclusions<p>While the existence of an AB was demonstrated, the carried-out body exposures were neither sufficient to reduce the AB nor the psychopathology; nevertheless, a significant decrease in anxiety levels showed the usefulness of the exposure sessions. …”

Table 1_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…Meanwhile, observations from drifters and buoys since 2001 have documented decreases in MCC current speed which has been linked to a climate driven strengthening of southwesterly winds. …”

Table 2_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…Meanwhile, observations from drifters and buoys since 2001 have documented decreases in MCC current speed which has been linked to a climate driven strengthening of southwesterly winds. …”

Table 1_The relationship between positive future thinking, entrapment, defeat and death-related mental imagery in individuals with and without a suicidal history: an experimental s... by Gonca Köse (21477470)

“…Mean scores for PFT from pre-to post-negative mood induction decreased significantly in the participants with a history of suicidal thoughts/behaviours but not in those without a suicidal history. …”

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX by Mingming Zhao (760369)

“…Nineteen identified metabolites, including five organic acids, four short-chain fatty acids, four amino acids, three fatty acids, and three benzenoids, differed significantly among the three groups, showing a strong association with VPA-induced hepatotoxicity. …”

Data Sheet 1_Impact of mini-dose dexmedetomidine supplemented analgesia on sleep structure in patients at high risk of obstructive sleep apnea: a pilot trial.docx by Pei Sun (115160)

“…</p>Setting<p>A tertiary university hospital in Beijing, China.…”

Image 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Table 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.xlsx by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Table 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Image 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Table 7_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.xlsx by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Table 3_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”

Image 7_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

“…</p>Results<p>Homozygous, crim1^−/− larvae demonstrated smaller eyes and small and misshapen lenses compared to controls, but we did not observe colobomas. Bulk RNA-Seq using dissected eyes from crim1^−/− larvae and controls at 72 h post fertilization showed significant downregulation of crim1 and chloride intracellular channel 4 (clic4) and upregulation of fibroblast growth factor 1b (fgf1b) and complement component 1, q subcomponent (c1q), amongst other dysregulated genes.…”