<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …”

Data Sheet 1_Splenic volume as a predictor of survival in cancer patients treated with immune checkpoint inhibitors.docx by Yunhua Zhang (231470)

“…Additionally, HCC patients who experienced an increase in spleen volume during ICI therapy exhibited significantly poorer OS (HR: 2.27, 95% CI: 1.17–4.41, p = 0.016) and PFS (HR: 2.40, 95% CI: 1.30–4.41, p = 0.005) than those whose spleen volume decreased. …”

NHR-49/80 mediated FEDUS via the peroxisomal activation. by Meiyu Ruan (19929335)

“…Lower population density significantly decreased palmitic acid-induced AWC maturation. …”

Scenarios.csv by Anna Lipinska (20427389)

“…Using empirical data and simulated scenarios of snow cover disappearance, we assess the impacts of varying winter temperature minima on population survival and growth.…”

GETM dataset - The major role of riverine outflows in shaping the current and future habitats of Harmful Algal Blooms : the case of the North Sea by Olaf Duteil (20376648)

“…These findings have significant implications for environmental policy and management.…”

Table 1_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.docx by Ming Qian (429232)

“…Conversely, salivary cortisol levels exhibited a decrease post-therapy, indicating a reduction in stress reactivity. …”

Data Sheet 1_Culture-based characterization of gut microbiota in inflammatory bowel disease.zip by Hyunjoon Park (6090965)

“…Consistent with our 16S rRNA gene amplicon sequencing results, a significant decrease in microbial diversity and a severe imbalance, especially in CD patients, were also observed in the culture-based analysis. …”

symulationvertigo.sce by Anna Lipinska (20427389)

“…Using empirical data and simulated scenarios of snow cover disappearance, we assess the impacts of varying winter temperature minima on population survival and growth.…”

Table 2_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.xlsx by Ming Qian (429232)

“…Conversely, salivary cortisol levels exhibited a decrease post-therapy, indicating a reduction in stress reactivity. …”

Data Sheet 1_Refinement of the novel tank diving test: toward standardized and robust analysis of anxiety-like behavior in zebrafish.docx by Takuro Shinkai (22518659)

“…We optimized the detection parameters for region entry and freezing behavior using logistic regression analysis, significantly reducing false-positive classifications caused by tracking artifacts. …”

Table 1_Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.docx by Mohamed A. Abdelnaim (16976001)

“…The mean Y-BOCS decreased from 31.11 at baseline to 16.50 at the last follow-up. …”

Nonadjacent dependency learning in Swiss toddlers (Bodard et al., 2025) by Julie Bodard (21715023)

“…However, at 27 months, we observed a significant decrease in gaze duration for ungrammatical test trials between the first and the second blocks, together with a tendency to look longer at grammatical stimuli in the second block, a pattern of results that, if confirmed in future studies, might indicate the start of novel NAD learning.…”

Data Sheet 1_Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study.pdf by Genwen Sun (22678739)

“…Three-level meta-regression models were implemented to examine the influence of study-level moderators, including age, sex, measurement level and comparison category.</p>Results<p>A significant decrease in CSA was observed only in osteoporotic patients compared with controls, and multiple muscle groups were evaluated. …”

Table 1_Diagnostic potential of WNT signaling gene methylation in pulmonary tuberculosis.doc by Hua Wang (13530)

“…The methylation levels of promoter region in WNT signaling pathway genes (SFRP1, WNT3A, CTNNB1, WIF-1, DKK-1, LRP5, LRP6) were detected by MethylTarget technique.</p>Results<p>We found that the methylation levels of SFRP1, WNT3A, CTNNB1, DKK-1, LRP6 genes were significantly decreased in the peripheral blood of PTB patients when compared to normal controls, while WIF-1, LRP5 genes methylation levels showed no significant difference between PTB patients and controls. …”

Data Sheet 1_The association between the gut microbiome and antituberculosis drug-induced liver injury.docx by Shengfei Pei (20852069)

“…</p>Results<p>Following anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”

Image 9_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.jpeg by Xiaqin Zhang (10211396)

“…Richness was significantly decreased from pre-treat to post-treat.…”

Table 1_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.xlsx by Xiaqin Zhang (10211396)

“…Richness was significantly decreased from pre-treat to post-treat.…”

Image 8_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.jpeg by Xiaqin Zhang (10211396)

“…Richness was significantly decreased from pre-treat to post-treat.…”

Image 5_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.jpeg by Xiaqin Zhang (10211396)

“…Richness was significantly decreased from pre-treat to post-treat.…”

Image 2_Genomic, transcriptomic, and T cell receptor profiling in stratifying response to first-line chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.jpeg by Xiaqin Zhang (10211396)

“…Richness was significantly decreased from pre-treat to post-treat.…”