Image 3_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

Table 1_Expansion of CD57+ CD8 T cells in common variable immunodeficiency with hepatopathy and CMV infection.pdf by Patrick Bez (13168041)

“…</p>Results<p>The expansion of CD57⁺ CD8 T cells was part of the previously described immune alteration, including altered CD4/CD8 ratio and a decrease in naïve CD4 T cells. The loss of significant association with increasing age might corroborate the suggestion of premature immunosenescence in CVID. …”

Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

DataSheet1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.PDF by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

Table1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.XLSX by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

3D modelling of the impact of stellar activity on tidally-locked terrestrial exoplanets: atmospheric composition and habitability (dataset) by R Ridgway (9137141)

“…We find that coronal mass ejections abiotically generate significant levels of potential bio-signatures such as N2O. …”

Table 2_Improved quality of life in head and neck cancer patients treated with modern arc radiotherapy techniques – A prospective longitudinal analysis.docx by Eva Yu-Hsuan Chuang (19724116)

“…Patients who received chemotherapy had significantly lower global QoL scales (mean difference, 27.94; 95% CI, 9.33-46.55; p=0.005). …”

Table 1_Improved quality of life in head and neck cancer patients treated with modern arc radiotherapy techniques – A prospective longitudinal analysis.docx by Eva Yu-Hsuan Chuang (19724116)

“…Patients who received chemotherapy had significantly lower global QoL scales (mean difference, 27.94; 95% CI, 9.33-46.55; p=0.005). …”

sRAGE accelerates regeneration in aged skeletal muscle after cryoinjury. by Naftali Horwitz (3130086)

“…Dots represent data for individual animals overlaid with mean ±  SD. Data analyzed for statistical significance by one-way ANOVA with Tukey post hoc test (A, D, G) or Student’s two-tailed unpaired t test (E, H, J, K, L, M). …”

Data Sheet 1_Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging.docx by Zhiqiang Qiu (4603993)

“…</p>Results<p>Compared to HCs, CNSP patients showed decreased mean FA values and increased mean MD values in bilateral intracranial STT compared to the HC group, but two-sample t-test results indicated no statistically significant differences (p > 0.05). …”

Supplementary file 1_Influence of circadian rhythm on the determination of the IMMune age indeX (IMMAX).docx by Sina Trebing (22578458)

“…</p>Results<p>While individual immune cell ratios showed changes during the day, we determined no significant variability of the IMMAX score between the measurements. …”

Raw data for hand and arm dysfunction following hemodialysis access placement by Kyoungrae Kim (10312460)

“…RESULTS: Six weeks post-surgery, patients exhibited significant functional decline in the access limb. Postoperative grip strength declined by approximately 15% (P=0.0015), finger pressure decreased by ~30 mmHg (P<0.0001), and the perceived HAD score increased significantly (P=0.0450) compared to the preoperative values. …”

Effects of vidarabine, V2E, V3E and V5E on cardiac fibrosis. by Kenji Suita (750993)

“…(B) Chronic ISO infusion significantly increased the area of fibrosis in cardiac muscle but this increase was significantly decreased by Vida, V2E, V3E and V5E. …”

Data Sheet 1_Global respiratory tumor mortality correlation study with economic level, 2000–2019.docx by Mingjie Wang (1719895)

“…</p>Results<p>The core cohort included 50 countries with sufficient data. The global mean ASMR for respiratory cancers showed a decreasing trend from 2000 to 2019. …”

EPB-113 binds to hexameric nsp15 protein. by Benjamin Van Loy (9496075)

“…The top panel shows the curves generated from the mean data of three independent experiments. The graph (bottom panel) shows the melting temperatures (individual and mean values) in three independent experiments. …”

Data Sheet 1_The effects of acupoint catgut embedding therapy on anthropometric parameters and endocrine function in obese women: a systematic review and meta-analysis.pdf by Shuangqiu Li (8083634)

“…Hormonal changes included decreased LH and FSH and increased E2.</p>Conclusion<p>Our meta-analysis demonstrates that ACET significantly improves anthropometric parameters and endocrine function in obese women, though it does not significantly impact lipid metabolism or insulin resistance. …”

Data Sheet 2_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Conclusion<p>This meta-analysis reveals gut microbiota imbalances in Chinese IBS patients: significantly increased Enterobacter and Enterococcus with decreased Lactobacillus and Bifidobacterium overall, and reduced Bacteroides specifically in IBS-D.…”

Data Sheet 1_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Conclusion<p>This meta-analysis reveals gut microbiota imbalances in Chinese IBS patients: significantly increased Enterobacter and Enterococcus with decreased Lactobacillus and Bifidobacterium overall, and reduced Bacteroides specifically in IBS-D.…”

Image 4_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…We aimed to explore the prognostic and predictive value of serum neuritin in ICH.…”

Image 6_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…We aimed to explore the prognostic and predictive value of serum neuritin in ICH.…”