Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel by Yuzhen Lu (4402591)

“…<p><i>Metarhizium robertsii</i>, a fungal pathogen employed in pest biocontrol, can alkalize the surrounding environment, although the biological implications remain unclear. Here, we found that <i>M. robertsii</i> glutamate dehydrogenase 2 (<i>MrGDH2</i>) was responsible for alkalization during fungal growth on insect wings or media containing cuticle powder. …”

Image 4_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg by Aleksandr Berezovski (20548583)

“…By examining the effects of these components across different seasons, we aimed to elucidate their relative contributions to light absorption and PP. …”

Image 3_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg by Kaleigh O’Hara (22750082)

“…We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …”

Supplementary Material for: The power of a good word: Enhancing the efficacy of analgesics in clinical settings by Treister R. (19801920)

“…In study 2, in the last two timepoints of assessment, participants in the EC arm also consumed fewer doses of opioids than participants in the RC arm (p<0.001). No significant differences were found in vital signs. Conclusions: We provide ecological evidence that positive information about treatment significantly decreases pain and opioid consumption during routine clinical care. …”

Table 2_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.docx by Yaser Shabanpour (13247160)

“…Using all-atom molecular dynamics simulations, we compared native red blood cell membranes (protein-free domains) with a ferroptosis model, in which PUFAs were replaced with hydroperoxide derivatives. …”

Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Table 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf by Yaser Shabanpour (13247160)

“…Using all-atom molecular dynamics simulations, we compared native red blood cell membranes (protein-free domains) with a ferroptosis model, in which PUFAs were replaced with hydroperoxide derivatives. …”

Data Sheet 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…Simulation results highlight key components affected, including thrombin, tissue plasminogen activator, plasmin, fibrin degradation products, interleukin 6 (IL-6), the IL-6 and IL-6R complex, and the terminal complement complex (C5b-9). We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Oral L-Arginine Treatment Attenuates<i>Cryptococcus neoformans</i>Extrapulmonary Dissemination and Disease Progression by Adithap Hansakon (21708473)

“…Key assessments included fungal burden quantification, inflammatory cell and cytokine characterization, brain gene expression analysis, histological examinations, and survival studies. We found significant depletion of serum L-arginine and its downstream metabolites, accompanied by increased arginase activity in infected tissues, indicating a disrupted metabolic balance. …”

Image 4_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg by Kaleigh O’Hara (22750082)

“…We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …”

Table 3_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.docx by Yaser Shabanpour (13247160)

“…Using all-atom molecular dynamics simulations, we compared native red blood cell membranes (protein-free domains) with a ferroptosis model, in which PUFAs were replaced with hydroperoxide derivatives. …”

Data_Sheet_1_MakC and MakD are two proteins associated with a tripartite toxin of Vibrio cholerae.pdf by Nandita Bodra (19793703)

“…Through deletion mutant analysis, we found that individual deletions of makC or makD do not significantly affect MakA expression or secretion. …”

Data Sheet 8_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…Simulation results highlight key components affected, including thrombin, tissue plasminogen activator, plasmin, fibrin degradation products, interleukin 6 (IL-6), the IL-6 and IL-6R complex, and the terminal complement complex (C5b-9). We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Data Sheet 1_Involvement of long non-coding RNA (lncRNA) MALAT1 in shear stress regulated adipocyte differentiation.docx by Justin Caron (21249173)

“…By leveraging a novel gapmer double stranded locked nuclei acid nanobiosensor, we showed that shear stress inhibits MALAT1 expression, with significantly reduced fluorescence intensity. …”

Table_1_Tick cysteine protease inhibitors suppress immune responses in mannan-induced psoriasis-like inflammation.docx by Huimei Wu (12087239)

“…Tick protease inhibitors have significantly decreased psoriasis symptoms and disease manifestations but had differential effects on inflammatory responses and immune cell populations, suggesting different modes of action of these inhibitors on psoriasis-like inflammation. …”

Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Data Sheet 15_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…Simulation results highlight key components affected, including thrombin, tissue plasminogen activator, plasmin, fibrin degradation products, interleukin 6 (IL-6), the IL-6 and IL-6R complex, and the terminal complement complex (C5b-9). We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 5_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg by Aleksandr Berezovski (20548583)

“…By examining the effects of these components across different seasons, we aimed to elucidate their relative contributions to light absorption and PP. …”

DataSheet1_Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.docx by Sayaka Suzuki (248729)

“…Consequently, the frequencies of exhausted CD8 T cells and regulatory T cells significantly decreased in the bone marrow of cDC1-depleted mice.…”

Table 1_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.docx by Lianjie Ruan (22660265)

“…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.…”