Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…All pemphigus patients demonstrated improved antibody responses after the third vaccination and none of them suffered from severe COVID-19 illness. Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…All pemphigus patients demonstrated improved antibody responses after the third vaccination and none of them suffered from severe COVID-19 illness. Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation. by Dilara Koc (22431017)

“…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …”

Data Sheet 1_Perceived protective behavioral changes in Chinese residents post-dynamic zero-COVID policy lifting: a cross-sectional study.docx by Yuan-Yuan Song (6287387)

“…The mean scores for the two vaccination-related items were significantly greater than the hypothesized no-change value of 2 (p < 0.001). …”

LC_MS/MS analysis for OGG1 interactomes. by Lang Pan (5145221)

“…Importantly, inhibiting OGG1’s ability to recognize 8-oxoGua significantly decreases RSV progeny production. Our results underscore the viral replication machinery’s adaptation to oxidative challenges, suggesting that inhibiting OGG1’s reading function could be a novel strategy for antiviral intervention.…”

Primer sequences for RT q-PCR. by Lang Pan (5145221)

“…Importantly, inhibiting OGG1’s ability to recognize 8-oxoGua significantly decreases RSV progeny production. Our results underscore the viral replication machinery’s adaptation to oxidative challenges, suggesting that inhibiting OGG1’s reading function could be a novel strategy for antiviral intervention.…”

Oligo sequences for EMSA and excision assay. by Lang Pan (5145221)

“…Importantly, inhibiting OGG1’s ability to recognize 8-oxoGua significantly decreases RSV progeny production. Our results underscore the viral replication machinery’s adaptation to oxidative challenges, suggesting that inhibiting OGG1’s reading function could be a novel strategy for antiviral intervention.…”

Supplementary file 1_Is a single calibration for the TloadDback cognitive fatigue induction task reliable?.docx by Jeromy Michael Hrabovecky (21781397)

“…Comparisons across the 3 calibration sessions (χ²(2) = 34.1, p < 0.0001) showed a significant STD decrease (i.e., performance improvement) with the most salient between sessions 1 and 2 (t = 3.98, p = 0.0003^***). …”

Genetic prediction of the relationship between mitochondrial proteins and diabetic polyneuropathy risk: a Mendelian randomization study by Zixiao Wang (6078317)

“…<p>This Mendelian Randomization (MR) study investigates the causal relationships between mitochondrial proteins and Diabetic polyneuropathy (DPN).</p> <p>Using a two-sample MR design with data from FINNGEN (1048 DPN cases, 374,434 controls) and 63 mitochondrial proteins from GWAS datasets. …”

DataSheet1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.PDF by Zhen Kang (335450)

“…</p>Results<p>In the UVMR result, genetic prediction showed that age at first sexual intercourse (AFS) (OR = 0.474, 95% CI 0.396–0.567; p = 4.6 × 10–16), age at first birth (AFB) (OR = 0.865, 95% CI 0.805–0.930; p = 8.02 × 10⁻⁵), and age at last live birth (ALLB) (OR = 0.296, 95% CI 0.138–0.636; p = 0.002) were significantly inversely associated with PPD, while a higher lifetime number of sexual partners (LNSP) (OR = 1.431, 95% CI 1.009–2.031; p = 0.045) and a greater number of spontaneous miscarriages (OR = 1.519, 95% CI 1.021–2.262; p = 0.039) are suggested to be associated with an increased risk of PPD. …”

Transgenic barley over-expressing <i>Aspergillus niger</i> phytase phyA in field trials by T Vlčko (22248667)

“…Increased phytase activity gradually decreased over the generations showing the most significant drop in the initial years of field trials. …”

<b>Evaluating Trauma-Focused Cognitive Behavioral Therapy in Earthquake Survivors: A Controlled Trial</b> by Metin Çınaroğlu (18498525)

“…Assessments were conducted using the PTSD Checklist (PCL), Beck Depression Inventory-II (BDI-II), and Beck Anxiety Inventory (BAI) at baseline, after the sixth and twelfth sessions, and at a three-month follow-up. Results showed substantial improvements in the treatment group, with PTSD scores decreasing from an average of 37.5 to 20.4, depression scores from 31.5 to 24.2, and anxiety scores from 31.5 to 24.2. …”

Dynamic network effects of right DLPFC-tDCS protocol (F4a-Fp1c). by Yanqing Dong (8829548)

“…Warmer colors indicate an increase in FC, while cooler colors indicate a decrease in FC. Color bars indicate statistical t-values (<i>p</i> < 0.05).…”

<b>Prevalence and Correlates of Diabetes Distress in Pregnant Individuals With Preexisting Diabetes: A Cross-Sectional Study</b> by Holly Tschirhart (823039)

“…Having a common-law partner or spouse, comorbid depression, depressive symptoms, and depression scores were all significantly associated with increased PAID scores (P <0.05). …”

Data Sheet 1_Effects of icariin as a feed additive on the reproductive function in bucks (Capra hircus).docx by Fang-e Zhao (20140809)

“…However, the serum concentration of GnRH in the ICA group initially increased, followed by a subsequent decrease (p < 0.05). The hypothalamic concentrations of dopamine (DA) and 5-hydroxytryptamine (5-HT) were significantly higher in the ICA group compared to the control group (p < 0.01). …”

Data Sheet 1_Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study.zip by Argul Issilbayeva (21398168)

“…</p>Conclusion<p>Our findings demonstrate that polyphenol supplementation maintains stable TMAO levels by restructuring gut microbiome composition in STEMI patients, evidenced by a more focused microbiome with a significant increase in beneficial butyrate-producing bacteria (Roseburia, Agathobaculum sp., Alistipes finegoldii, and Sellimonas) and a decreased Firmicutes/Bacteroidetes ratio, suggesting microbiome-mediated cardioprotective effects. …”

Supplementary Material for: Acute interstitial nephritis associated to Pertussis infection: a case report and review of the literature by figshare admin karger (2628495)

“…Case Presentation: A 73-year-old male with a history of systemic arterial hypertension, dyslipidemia, and previous left nephrectomy presented with a five-day history of fatigue, fever, cough, and nasal obstruction. …”

Datasheet1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

Table2_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

Table1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”