DataSheet1_Cross-National Trends in Early Sexual Initiation Among 15-Year-Old Adolescents, 2002–2022.xlsx by András Költő (10831323)

“…Parental support (and its interaction with time) also had a significant but small protective role.</p>Conclusion<p>Despite a small decrease over time, still 4% of participants reported early sexual initiation in 2022. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein by Zili Li (20425625)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Data Sheet 1_Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial.pdf by Li-qin Meng (20633030)

“…</p>Methods<p>Based on randomization, we administered oral FFDS to 30 patients with SCHD in addition to conventional treatment for 30 days. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”

Table 1_Effect of Ebenatide on glycemic metabolism and body fat in patients with type 2 diabetes mellitus.docx by Cheng-lan Xu (21562694)

“…The triglyceride-glucose index (TyG) decreased at Week 52 compared with baseline (P<0.01). …”

Table 1_Declining trends in sweetness of the diet in the United Kingdom: 2008/9–2018/19.docx by Inga Kutepova (20873687)

“…Overall, the decline in ASE was larger for beverages than foods (ASE values declined 20.7% for beverages vs. 4.4% for foods), although both decreased significantly (p-value < 0.01). …”

Table_1_A causal association between obesity and constipation: a two-sample bidirectional Mendelian randomization study and meta-analysis.XLSX by Xian Sun (655494)

“…Objective<p>Observational studies suggest a potential link between obesity and constipation, but existing results are conflicting. Therefore, we conducted a Mendelian randomization (MR) study and meta-analysis to assess the causal relationship between obesity and the risk of constipation.…”

Data_Sheet_1_A causal association between obesity and constipation: a two-sample bidirectional Mendelian randomization study and meta-analysis.zip by Xian Sun (655494)

“…Objective<p>Observational studies suggest a potential link between obesity and constipation, but existing results are conflicting. Therefore, we conducted a Mendelian randomization (MR) study and meta-analysis to assess the causal relationship between obesity and the risk of constipation.…”

Mapping the properties of cells in relation to their local neighborhood. by Matthew French (13007466)

“…Local heterogeneity (CV) in TBX6 is greater than TBXT, which is greater than local heterogeneity in SOX2. …”

Data Sheet 1_Fungal planktonic community related to salinity and temperature in an oligotrophic sea.docx by Ashwag A. Asseri (20633438)

“…Our results showed that Chytridiomycota dominated these communities, accounting for 85% of reads, followed by members of the divisions Basidiomycota (4.7%) and Cryptomycota (4.13%). Interestingly, we found that fungal communities did not exhibit significant changes with depth or chlorophyll concentration. …”

Data Sheet 2_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... by Yao Wang (102387)

“…</p>Conclusion<p>In conclusion, although SGLT2i increase the risk of EKA and GUI and GLP-1RA decrease the risk of AKI, SGLT2i are at comparable risk of MACE, HHF, MI, stroke, hypoglycemia, and fracture to GLP-1RA.…”

Data Sheet 1_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... by Yao Wang (102387)

“…</p>Conclusion<p>In conclusion, although SGLT2i increase the risk of EKA and GUI and GLP-1RA decrease the risk of AKI, SGLT2i are at comparable risk of MACE, HHF, MI, stroke, hypoglycemia, and fracture to GLP-1RA.…”

Table 1_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes mell... by Yao Wang (102387)

“…</p>Conclusion<p>In conclusion, although SGLT2i increase the risk of EKA and GUI and GLP-1RA decrease the risk of AKI, SGLT2i are at comparable risk of MACE, HHF, MI, stroke, hypoglycemia, and fracture to GLP-1RA.…”

Table 1_Comparative analysis of soil properties before and after Morchella sextelata cultivation across various soil types.xlsx by Juan Zhao (109151)

“…In this study, our results reveals that cultivation significantly alters soil properties and microbial communities in a soil type-dependent manner. …”

Image 1_Markers of immunosenescence in CMV seropositive healthy elderly adults.tif by Ivón Johanna Rodríguez (20601272)

“…In this sense, this work aimed to identify senescence markers in cells of the innate and adaptive immune system in healthy older adults with CMV infection. We observed that older adults present an increase in the population of CD14⁺CD16⁺ intermediate monocytes, an expansion of CD56neg NK cells with an increase in the expression of CD57, as well as a decrease in the naïve CD4⁺ and CD8⁺ T cells, accompanied by an increased expression of senescence markers CD57 and KLRG1 in effector CD8⁺ T cells.…”

<b>Global pattern and drivers of disease heterogeneity in aging populations</b> by Chengcheng Jin (20326186)

“…We observed significant geographic variations in disease heterogeneity, with higher SHDI values in high-income Western countries such as the United States of America and Sweden and lower in South Asia and Oceania (p < 0.05). …”

Prognostic indicators and survival rates in vulvar cancer: insights from a retrospective study by Tharinee Rahong (21020147)

“…Multivariate analysis indicated that coexisting lesions such as Paget’s disease and lichen sclerosus, positive lymphovascular space invasion (LVSI), pelvic or para-aortic lymph node involvement, and positive p53 expression were significantly linked to reduced PFS. Additionally, a tumour size greater than 4 cm was associated with decreased OS. …”

Data Sheet 1_Can posttreatment blood inflammatory markers predict poor survival in gynecologic cancer?: a systematic review and meta-analysis.xlsx by Minyong Choi (22465405)

“…Furthermore, among the inconsistent blood draw timing and analytical methods, we aimed to suggest the most suitable strategies in the clinical setting.…”

Table 2_Associations between physical fitness components and metabolic syndrome in middle-aged adults: a cross-sectional study using relative strength indicators and ROC analysis.d... by Zhanfei Zheng (22629227)

“…In this cross-sectional study, we investigated the association between multiple fitness components and the presence of MetS in middle-aged adults, with emphasis on weight-normalized indices.…”

Data Sheet 1_Effects of continuous cropping on soil metabolomics and rhizosphere bacterial communities in Panax quinquefolius L..docx by Jian Song (4232)

“…Microbial community composition was assessed using Illumina high-throughput sequencing, and metabolite profiles were analyzed using non-targeted metabolomics (UPLC-MS/MS).</p>Results<p>Significant decreases were observed in soil pH (12.2–28.0%), cation exchange capacity (42.6–65.5%), organic matter (8.7–27.3%), total nitrogen (7.6–27.8%), and ammonium (NH₄⁺) content (16.9–56.6%) with an increasing number of continuous cropping years. …”