Table 2_Gut metagenomic features of frailty.xlsx by Zharkyn Jarmukhanov (19743034)

“…Taxonomically, we observed a significant inverse correlation between Firmicutes abundance and frailty. …”

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…In both our highlighted case and in our aggregate data, we report significant improvement in wall thickness, mitral regurgitation, left ventricular outflow tract obstruction and New York Heart Association symptom class. …”

Table1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.docx by Sheena I. Dev (20293434)

“…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …”

Image1_Cognitive performance in ISS astronauts on 6-month low earth orbit missions.pdf by Sheena I. Dev (20293434)

“…There was slowed performance observed in early flight on tasks of processing speed, visual working memory, and sustained attention. We observed a decrease in risk-taking propensity during late flight and post-flight mission phases. …”

Data Sheet 1_The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.pdf by Sijie Zhang (7429373)

“…Furthermore, we also found significant associations between this variant and IGI, corrected insulin response (CIR), and DIo (All P < 0.001) in female individuals whose waist-to-hip ratio (WHR) is greater than 0.85, with considerable heterogeneity (P_het = 0.009, 0.030, and 0.049, respectively) to male participants in the NGT individuals, but not in the impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) individuals. …”

Data Sheet 1_White matter functional networks in the developing brain.docx by Yali Huang (621760)

“…Significant developmental differences in brain white matter functional networks exist between the two group, characterized by increased inter-network FC, decreased intra-network FC, and higher high-frequency energy distribution. …”

Data Sheet 1_miR-198 targets TOPORS: implications for oral squamous cell carcinoma pathogenesis.pdf by Pankhuri Kaushik (20381022)

“…Delivery of a synthetic miR-198 mimic to OSCC cells results in a significant decrease in xenograft size in nude mice, potentiating its use in therapeutics.…”

Table 1_Trends in the burden of urolithiasis in China: an analysis from the global burden of disease study 2021.xlsx by Yangyang Lin (3797422)

“…</p>Conclusion<p>In this study, we analysed the trend of the disease burden of urolithiasis in China during 1992–2021 by GBD 2021. …”

Raw data for Figs 1, 2, 3, 4 and S2. by Areej A. Alfaifi (20422411)

“…Bulk RNA-sequencing of parotid salivary glands from COVID-19 autopsies demonstrated statistically significant decreased expression of histatin and amylase genes. …”

Data Sheet 1_Global, regional, and national burden of pneumococcal disease among children and adolescents aged <20 years from 1990 to 2021: a predictive analysis.docx by Gan-min Wang (21188933)

“…Background<p>Pneumococcal infections remain a leading cause of preventable deaths among children and adolescents aged <20 years. Despite a global decrease in burden, significant regional and socioeconomic disparities, as well as long-term trends, are not fully understood.…”

Supplementary Material for: Global, Regional, and National Burden of Neonatal Encephalopathy Due to Birth Asphyxia and Trauma, Its Attributable Risk Factors, 1990-2021: Results fro... by figshare admin karger (2628495)

“…Low SDI regions experienced a substantial 112.9% increase in NEBAT cases, while high-middle SDI regions witnessed a significant 34.8% decrease. Although mortality rates declined across all SDI regions, the low SDI region had the smallest decline. …”

Data Sheet 1_Clinical predictors and concomitant antiseizure medications effects on seizure control in relation to plasma cenobamate concentration: a multicenter retrospective stud... by Francesca Felicia Operto (12509263)

“…Among responders, 53.8% (14/26) achieved response on ≤100 mg/day, with CNBp of 0.5–17.6 μg/mL (median ∼5–6 μg/mL). There was no significant relationship between age and gender, although there was a statistically significant correlation between CNBp and BMI (p = 0.038; R2 = 0.157). …”

Integrated bioinformatic and experimental study links cyclin B1/B2 to poor prognosis and immune infiltration in endometrial cancer by Haikun Yang (14815742)

“…In TCGA cohort, high expression of CCNB1/CCNB2 correlated with greater disease severity and predicted poor prognosis. …”

Data Sheet 1_The impact of cell density variations on nanoparticle uptake across bioprinted A549 gradients.docx by Luigi Di Stolfo (21216599)

“…This inverse relationship correlated with greater average cell surface area in lower-density regions, while differences in the proliferation rates of the A549 cells at varying densities did not significantly impact uptake, did not significantly impact uptake.…”

Table 1_Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution.docx by Ning Yu (358970)

“…Compared with those in the NPDC or BC group, the relative abundances of o_RF39, f_Porphyromonadaceae, f_Christensenellaceae, g_parabacteroides, and g_nitrobacteria in the PDC group were significantly greater. The random forest analysis results revealed that Alistipes, Butyricimonas, Odoribacter, Parabacteroides, and Corynebacterium are bacterial genera that significantly differ between the PDC and NPDC groups and greatly contribute to group differentiation. …”

Efficacy of Shenkang Injection combined with renin-angiotensin-aldosterone system blockers in diabetic nephropathy: a systematic review and meta-analysis of randomized controlled t... by Xinyue Zhang (271120)

“…Urinary protein excretion rate (UPER), serum creatinine (SCr), blood urea nitrogen (BUN), 24-hour urinary protein (24h-UTP), total cholesterol (TC), and triglyceride (TG) levels all significantly decreased in the combination group. Subgroup analysis showed that patients aged ≤55 years had greater reductions in SCr (WMD −25.62, 95% CI −29.41 to −21.83) and BUN (WMD −2.51, 95% CI −2.75 to −2.27). …”

Consort flow diagram of the participants. by Preeyaphorn Songsorn (21799601)

“…During flow incentive spirometry, stroke volume and heart rate significantly increased, while cardiac output significantly decreased compared to volume incentive spirometry and costal breathing exercises with sustained maximal inspiration throughout the 10 breathing cycles.…”

Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study by ShaSha Li (12163175)

“…Individuals with AKI were prospectively followed up for 90 days to determine the association between their average sKlotho level and short-term AKI outcomes. Interestingly, we found that sKlotho value was significantly decreased and an alteration in the sKlotho level ran parallel to changes in kidney function in AKI patients. …”

Data Sheet 1_Rice glycosyltransferase OsDUGT1 is involved in heat stress tolerance by glycosylating flavonoids and regulating flavonoid metabolism.doc by Guang-rui Dong (11871026)

“…Correspondingly, the loss of OsDUGT1 function caused a significant decrease in endogenous flavonoid accumulation in rice, which was demonstrated by our metabolomics analysis. …”

Table 1_Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study.docx by Katarzyna Kosinska-Kaczynska (6794522)

“…However, in both sites none difference was found to be statistically significant after p-value correction.</p>Conclusions<p>Despite small sample size, we demonstrated slight trends in microbiota composition between groups. …”