Data Sheet 4_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Data Sheet 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Table 1_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.docx by Dongli Cao (18700097)

“…</p>Results<p>We identified two functionally distinct endothelial subpopulations: 1. …”

Minimal data sets. by Razia Rashid Rahil (22772495)

“…Sphingolipids such as ceramide (CER) mediates inflammation and VC in the vascular tissue. We investigated whether evogliptin ameliorate phenotypic transition and pyroptosis in VSMCs as underlying cause of VC. …”

Data Sheet 2_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.docx by Chao Xue (503328)

“…</p>Results<p>We found that HBOT alleviated aGVHD in mice, which was associated with a significantly prolonged overall survival (OS) and reduced pathological injury, whereas Nrf2 inhibition had the opposite effect. …”

Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX by Sara R. Oliveira (10972152)

“…LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. Finally, in SH-SY5Y neuroblastoma cells, miR-335 decreased the expression of pro-inflammatory genes triggered by α-synuclein. …”

Data Sheet 1_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.pdf by Chao Xue (503328)

“…</p>Results<p>We found that HBOT alleviated aGVHD in mice, which was associated with a significantly prolonged overall survival (OS) and reduced pathological injury, whereas Nrf2 inhibition had the opposite effect. …”

pone.0337200.t001 - by Razia Rashid Rahil (22772495)

“…Sphingolipids such as ceramide (CER) mediates inflammation and VC in the vascular tissue. We investigated whether evogliptin ameliorate phenotypic transition and pyroptosis in VSMCs as underlying cause of VC. …”

Data Sheet 1_Impact of large-scale oceanic variability on Adriatic fisheries evidenced through the ‘mean temperature of the catch’ approach.docx by Elvis Kamberi (22759586)

“…<p>Climate change is significantly impacting marine ecosystems, altering their structure and functioning by influencing all levels of organization. …”

Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Supplementary Material for: Single intraluminal delivery of a nitric oxide-donor results in inhibition of intimal thickening in the rabbit femoral artery by Böttger P. (20682794)

“…Linsidomine treatment decreased the intima media ratio significantly (0.65±0.05 vs 1,2±0.2 intima-media-ratio, p<0.05). …”

Whole 16S rRNA gene sequencing reveals differences in the oral microbiota of healthy individuals infected with oral HPV by Toby I. Maidment (15296219)

“…Statistical analysis of alpha- and beta-diversity, as well as taxonomic composition (differential abundance testing), were used to determine differences between-subject groups.</p> <p>We demonstrated (1) significant differences in the abundance of <i>Streptococcus salivarius</i> in oral HPV-negative males; (2) males with low-risk HPV had an increased abundance of several species and (3) decreased abundance of <i>Streptococcus salivarius</i> and <i>Streptococcus parasanguinis</i>. …”

Supporting data for "Excess mortality during the COVID-19 pandemic in Hong Kong and South Korea" by Shuqi Xu (12992556)

“…Mortality from influenza and pneumonia was estimated to have a statistically significant increase in HK but a decrease in SK probability due to different coding practices. …”

<b>Sex-specific anti-inflammatory effects of a ketogenic diet in a mouse model of allergic airway inflammation</b> by Carolyn Ekpruke (17014107)

“…Male and female mice were fed either a KD or normal chow and exposed to house dust mite allergens. Results revealed significant sex-diet interactions in lung immune cell populations, with males showing greater reductions in eosinophils, increased NKT cells, and decreased NK cells. …”

Image 1_Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11.tif by Li Ling (424480)

“…Moreover, the combination of SAS and ¹³¹I significantly increased the MDA levels and lipid peroxidation, decreased the GSH levels, and suppressed the expression of SLC7A11 and GPX4, while SLC7A11 knockdown significantly enhanced ferroptosis-related markers in DTC cells. …”

Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio... by Liming Liu (107470)

“…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …”

Table 1_Effects of two kinds of vestibular function training on reducing motion sickness in college students.docx by Linyao Shi (20684204)

“…</p>Results<p>After training, both groups’ Graybiel scores, blood pressure, high-frequency power (HF), and root mean square of successive differences (rMSSD) between adjacent normal heartbeats significantly decreased. In the visual-motion cage rotating chair group, in addition to a reduction in the percentage of adjacent normal-to-normal intervals which differed by more than 50 ms (pNN50), as well as decreases in low-frequency power (LF), an increase in LF/HF was observed. …”

Table 2_Outcomes after therapeutic SBE-ERCP for choledochojejunal/hepaticojejunal anastomotic stenosis after bile duct injury.docx by Yijun Shu (3456728)

“…Background<p>Choledochojejunal/hepaticojejunal anastomotic stenosis (CJS/HJS) is significant clinical problem associated with decreased survival postsurgery. …”

Image 1_PipC affects the virulence of Salmonella enterica serovar Enteritidis and its deletion strain provides effective immune protection in mice.tif by Lu Zhang (50563)

“…Meanwhile, the expression levels of SPI-1-related genes (invH, sipA, sipB, sipC, sopB, and sopE2) and SPI-2-related genes (spvB, ssrA, orf245, ssaS, ssaT, ssaU, sseB, and sseD) encoding the Salmonella type III secretion system (T3SS) were found to be decreased, leading to a significant reduction in the bacteria’s invasion and intracellular survival abilities. …”