Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…Moreover, in our center's experience, neither arrhythmia burden, nor contractility have worsened in the vast majority of patients: we note a clinically insignificant mean decrease in left ventricular ejection fraction (LVEF), with only two patients requiring temporary mavacamten discontinuance for LVEF < 50%. …”

Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx by Pamela Mda (20390050)

“…Nevertheless, some pregnancies occur in almost all studies. We examined contraceptive use, pregnancy incidence, and the relationship between pregnancy and HIV seroconversion in one HIV vaccine trial.…”

Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. by Michelle So (400874)

“…Beta2 score, derived from fasting glucose, C-peptide, HbA1c and insulin dose at 12 weeks, was optimal for predicting QRS>0 following one year of treatment with baricitinib and the other immunotherapies (areas under receiver-operator curve 0.864 and 0.765 respectively). A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…”

Data Sheet 1_Hemodynamic changes and their relationship with white matter hyperintensities in CSVD patients with cognitive impairment: a 4D flow study.pdf by Jiajun Cao (11560062)

“…There was a moderately positive correlation between MMSE, MoCA score and flow rate, flow velocity, and WSS (r = 0.226–0.544, all P < 0.05), and a moderately negative correlation between MMSE, MoCA score and PI, RI (r = −0.230 to −0.406, all P < 0.05). Multiple linear regression indicated that, the flow rate and mean velocity in venous sinuses (β = −0.472 to −0.381, all P < 0.05) and the WSS in arterial segments (β = −0.771 to −0.441, all P < 0.05) had independently negative association with WMH burden; Meanwhile, a significant positive relationship was found between PI in arterial segments and specific-distributed WMH (PVWMH and S-CC WMH) (β = 0.239 to 0.356, all P < 0.05).…”

Comparative Analysis of Gut Microbiota in Collegiate Swimmers Following Changes in Exercise by Jarrad Hampton-Marcell (695263)

“…Peak training volume, measured as swimming distance, decreased significantly during the study period from 32.6 ± 4.8 km/wk to 11.3 ± 8.1 km/wk (ANOVA, p < 0.05); however, body composition showed no significant changes. …”

Image 1_Evaluation of clopidogrel impact on canine platelet function using flow cytometry and thromboelastography platelet mapping.tif by Eunchae Yoon (21487805)

“…Flow cytometry confirmed the marked inhibition of platelet activation, with significant decreases in the percentage of CD62P positive platelets and the mean fluorescence intensity under ADP and epinephrine stimulation (p < 0.05). …”

Table 1_Single and consecutive 10-day remote ischemic preconditioning modify physical performance, post-exercise exerkine levels, and inflammation.docx by Magdalena Kochanowicz (20153682)

“…Similarly, a significant 15.5% (p < 0.05) decrease in the IL-6 concentration 120 min after the WAnT was observed only in the consecutive 10-day RIPC protocol, as well as a 12.2% (p < 0.01) increase in oncostatin M 60 min after the WAnT.…”

Table 1_Uncaria tomentosa extract exerts antimicrobial activity against boar seminal bacteria and influences sperm resilience under different conditions.xlsx by Maria Scaringi (18815462)

“…During semen storage, the extract did not show any cytotoxicity, and mean values of some sperm parameters were higher than the control group, although not significant (p > 0.05). …”

Data Sheet 1_Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study.pdf by Rebecca Lyng Holm (20620406)

“…Milk was collected before exercise/rest (at 07:00 h), immediately after exercise/rest (11:00 h), 1 h after exercise/rest (12:00 h), and 4 h after exercise/rest (15:00 h). We determined insulin concentrations in the milk using enzyme-linked immunosorbent assay and compared insulin concentrations after MICT and HIIT with REST using a linear mixed model with time-points and the interaction between time and condition as fixed factors.…”

Table_1_Association between serum iron levels and atherosclerotic cardiovascular diseases among American older adults: a cross-sectional study based on the National Health and Nutr... by Xiaochen Yu (3796927)

“…For serum iron levels below 131 μg/dL, each 10 μg/dL increase was associated with a 4% decrease in the odds of ASCVD (OR = 0.96; 95% CI, 0.93–0.98, p < 0.001). …”

Data Sheet 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.pdf by Yihong Yang (557831)

“…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …”

Table 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.xls by Yihong Yang (557831)

“…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …”

Data Sheet 1_Postoperative pain outcomes following uniportal vs. multiportal video-assisted thoracoscopic surgery: a systematic review and meta-analysis.pdf by Fahim Kanani (22589672)

“…Meta-regression identified a decrease in effect sizes over time (β = 0.05 per year, p = 0.024). …”

Supplementary Material for: The impact of laparoscopic cystectomy for ovarian endometrioma on anti-Mullerian hormone levels: a systematic review and meta-analysis by figshare admin karger (2628495)

“…Primary outcomes showed a statistically significant (P < 0.001) decrease in anti-Müllerian hormone in the postoperative short-term period [-1.39 ng/mL, 95% CI, -2.01- (-0.76)], medium term period [-1.13 ng/mL (95% CI, -1.4- (-0.87)], and long term [-2.12 ng/mL (95% CI, -2.61- (-1.63)]. …”

Table 1_Association between relative fat mass and risk of arthritis: a study based on populations in China and the United States.docx by Yang Yang (45629)

“…In the American female population, a non-linear correlation was observed between RFM and arthritis, with elevated RFM below the threshold of 35.85 exhibiting a modest decrease in the risk of arthritis, and elevated RFM above the threshold demonstrating a substantial increase in the risk of arthritis. …”

Datasheet1_Physiological characteristics of blood pressure responses after combined exercise in elderly hypertensive patients: a systematic review and meta-analysis.pdf by Zhiheng Li (525468)

“…</p>Results<p>In comparison to the control group (n = 194), individuals enrolled in the combined exercise group (n = 200) exhibited a notable decrease in both resting systolic blood pressure (SBP) [weighted mean difference (WMD) = −11.17 mm Hg, 95% confidence interval (CI) (−17.13, −5.22), Z = 3.68, P < 0.05] and diastolic blood pressure (DBP) [WMD = −5.93 mm Hg, 95% CI (−9.24, −2.61), Z = 3.51, P < 0.05]. …”

Table 1_Effect of a mindfulness-based cognitive behavior therapy intervention on occupational burnout among school teachers.docx by Netra Raj Paudel (20610806)

“…</p>Results<p>The mean level of EE decreased during the post-test for both treatment (mean change -0.93, 95% CI: -2.56 to 0.70) and control (-1.71, 95% CI: -3.24 to -0.18) arms. …”

The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil by Ilza Monteiro (10459778)

“…</p> <p>Fully completed questionnaires were received from 541 physicians aged (mean ± SD) 46.6 ± 12.5 years. Whereas the overall number of AUB-related visits decreased (<i>p</i> < 0.001) compared to the pre-pandemic period, the reduction was in office-based encounters; AUB-related visits at emergency facilities did not change. …”

Sleep deprivation by payam saidie (20329440)

“…Furthermore, in the NSP group, a significant decrease was observed at BASE compared to 60 min-PS (P ≤ 0.05) (20.72%).…”

BMI and sex disparity in uric acid level improvement in patients with obesity and diabetes following laparoscopic sleeve gastrectomy by Bian Wu (111324)

“…For lipid metabolism, a significant linear correlation was only observed between UA level changes and HDL in female and those with high presurgical UA levels.…”