Exploring the protective role of DDIT4/mTOR in podocyte integrity through macrophage polarization in diabetic kidney disease حسب Jingxuan Shi (10807695)

"…<p>In this study, we explored the mechanism by which DDIT4 influences the polarization phenotypic transformation of macrophages and inflammation through the regulation of mTOR signaling pathway, providing a new mechanism and target for the treatment of diabetic nephropathy.…"

Microbial Alliances: Unveiling the Effects of a Bacterial and Fungal Cross-Kingdom SynCom on Bacterial Dynamics, Rhizosphere Metabolites, and Soybean Resilience in Acidic Soils حسب Zhongling Wen (13878743)

"…The native RhRi SynCom outperformed EfRi, significantly improving soybean growth, yield, and soil health. …"

Table 1_Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course.docx حسب Elisabetta Zucchi (9527077)

"…</p>Results<p>Our study showed that Treg levels did not change significantly on average during the observation period in our ALS cohort. …"

Image 1_Effects of different additives on fermentation quality, mycotoxin concentrations, and microbial communities in high-moisture corn kernels during wet storage.tif حسب Xingya Wang (3126705)

"…In contrast, despite higher lactic and acetic acid levels in the EN treatment, the pH did not decrease significantly due to higher NH₃-N content. …"

<b>Triptolide alleviates </b><b>cognitive</b><b> impairment via </b><b>autophagy</b><b> and Akt/mTOR/p70S6K pathway in an APP/PS1 Alzheimer’s disease mouse model</b> حسب xinyao Qi (21686459)

"…</p><p dir="ltr">The Morris Water Maze (MWM) test assessed cognitive function, where TP treatment significantly decreased escape latencies in AD mice without affecting swimming speeds, suggesting improved spatial learning and memory independent of motor function. …"

Table 1_Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observat... حسب Yuya Koide (22261300)

"…</p>Results<p>GLP-1RA therapy significantly reduced HbA1c, body weight, and body fat percentage at 12 months. …"

Image 2_Effects of different additives on fermentation quality, mycotoxin concentrations, and microbial communities in high-moisture corn kernels during wet storage.tif حسب Xingya Wang (3126705)

"…In contrast, despite higher lactic and acetic acid levels in the EN treatment, the pH did not decrease significantly due to higher NH₃-N content. …"

Table 1_Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management.docx حسب Junming Chen (3603422)

"…Multimodal management combining pharmacotherapy (escitalopram, tandospirone), transcranial magnetic stimulation (9 sessions), biofeedback (14 sessions), psychotherapy, and lifestyle interventions achieve: mean BP decreased significantly from 176/105 mmHg to 125/72 mmHg during hospitalization; significant anxiety reduction (HAMA = 3), mean BP stabilized at 131/77 mmHg with 50% reduction in antihypertensive dosages, normalization of elevated ACTH (99.9→normal pg/mL) and cortisol (18.7→normal μg/dL) and sustained improvement at 6-month follow-up.…"

Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx حسب Juanjuan Fang (413481)

"…RCS showed a non-linear negative trend for DI-GM (p < 0.001; nonlinear p = 0.046) and a non-linear association for DI-GM beneficial (p < 0.001; non-linear p = 0.023) with sleep disorders. …"

Data Sheet 1_Artificial intelligence-assisted delineation for postoperative radiotherapy in patients with lung cancer: a prospective, multi-center, cohort study.docx حسب Ziming Han (19926057)

"…In addition to better contouring accuracy, the AI-assisted delineation significantly decreased the consuming time and improved the efficiency.…"

<b>Efficacy of </b><b>GLP-1-based Therapies on</b><b> </b><b>Metabolic Dysfunction-Associated Steatotic</b><b> Liver Disease and </b><b>Metabolic Dysfunction-Associated</b><b> Stea... حسب Yahao Wang (21291242)

"…GLP-1RAs treatment significantly decreased serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) andγ-glutamyl transferase (GGT) compared with control. …"

Table 1_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 7_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 3_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 6_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 2_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 5_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Table 4_Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence.docx حسب Aling Tang (17523700)

"…In vivo experiments confirmed a significant decrease in serum 25(OH)D levels in CLP group mice compared to the Sham group (Sham: 90.7 ± 1.7 vs. …"

Impact of Oral Semaglutide on Kidney Outcomes in People with Type 2 Diabetes: Results from the SOUL Randomized Trial حسب Johannes F. E. Mann (22017555)

"…</p><p dir="ltr">RESULTS</p><p dir="ltr">Among 9,650 participants, mean eGFR was 73.8 mL/min/1.73 m2 and follow-up was 47.5 months. …"

Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx حسب Zhi Shang (4849129)

"…Renal function decline was defined as an estimated glomerular filtration rate decreasing by ≥ 40% from baseline. All participants were categorized into tertiles according to the systemic inflammatory indices. …"