Table 4_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Table 3_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Table 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.xlsx حسب Meng Yi (7853249)

"…IL1R1 emerged as the most significant risk factor. scRNA-seq revealed altered cellular composition in diabetic discs, notably increased proportion of granulocytes (predominantly neutrophils) and decreased proportion of nucleus pulposus (NP) cells. …"

Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx حسب Yuchen Liang (8596404)

"…To investigate the mechanisms underlying cold tolerance in L. angustifolia and support economic development, we measured the sugar content and performed transcriptome analysis at temperatures of 30°C (control), 20°C, 10°C, and 0°C. …"

Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf حسب Irina A. Strigo (9745472)

"…</p>Results<p>MyP led to significant decreases in PEG scores overall. Furthermore, MyP responders exhibited increased pain-related activation in key brain regions, including the contralateral posterior insula, bilateral ventral anterior insula, ventral anterior cingulate, dorsolateral prefrontal cortex, and nucleus accumbens. …"

<b>Canagliflozin-induced adaptive metabolism in bone</b> حسب Sher Bahadur Poudel (20686192)

"…We studied the impact of 1, 3, or 6 months of canagliflozin (CANA), an SGLT2i treatment, on the skeleton of 6-month-old genetically heterogeneous UM-HET3 mice. …"

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"

Table 4_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"

Data Sheet 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.zip حسب Xi Luo (361139)

"…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …"

Table 2_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"

Loss of b-cell K_ATP reduces Ca²⁺ sensitivity of insulin secretion and <i>Trpm5</i> expression حسب Nathaniel W. York (20410828)

"…Paradoxically, despite the initial insulin hypersecretion, many CHI cases, as well as K_ATP knockout (KO) animals, eventually ‘crossover’ to undersecretion and even diabetes. Here we confirm that S<i>ur1</i> KO islets exhibit higher intracellular [Ca²⁺] (<a href="" target="_blank">[Ca²⁺]_i</a>) at all [glucose], but show decreased glucose-stimulated insulin secretion. …"

Table 3_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"

Table 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.docx حسب Xi Luo (361139)

"…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …"

VB2 cell fate analysis of <i>hlh-17</i>, <i>hlh-31</i>, and <i>hlh-32</i> mutant animals. حسب G. Robert Aguilar (13889674)

"…Error bars indicate standard deviation of the mean. ****<i>p</i> ≤ 0.0001, *<i>p</i> ≤ 0.05, ns: not significant. …"

DataSheet1_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx حسب Patrick Yawo Kpai (20376234)

"…<p>Cannabis cultivated for medical and adult use is a high-value horticultural crop in North America; however, we lack information on its optimal mineral nutrition due to previous legal restrictions. …"

DataSheet2_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx حسب Patrick Yawo Kpai (20376234)

"…<p>Cannabis cultivated for medical and adult use is a high-value horticultural crop in North America; however, we lack information on its optimal mineral nutrition due to previous legal restrictions. …"

Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl... حسب Caroline V. Cameron (22355207)

"…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …"

Bacterium-Phage Symbiosis Facilitates the Enrichment of Bacterial Pathogens and Antibiotic-Resistant Bacteria in the Plastisphere حسب Rong Xia (30438)

"…The plastisphere phage community exhibited decreased diversity and virulent proportion compared to those found in environments. …"

Pilot study on the impact of HIFU treatment on miRNA profiles in vaginal secretions of uterine fibroids and adenomyosis patients حسب Wei-Chun Chen (276732)

"…Notably, hsa-miR-7977, hsa-miR-155-5p, hsa-miR-191-5p, and hsa-miR-223-3p showed significant changes in fibroid cases, except in low-energy treatments. hsa-miR-7977 consistently decreased post-treatment, while hsa-miR-155-5p decreased in the least efficient cases. …"

Supplementary file 1_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.docx حسب Yiwei Yue (22307683)

"…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …"