<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…We studied the impact of 1, 3, or 6 months of canagliflozin (CANA), an SGLT2i treatment, on the skeleton of 6-month-old genetically heterogeneous UM-HET3 mice. …”

Table 1_Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome.docx by Miaohong Wang (8975903)

“…The impact of age was significant, with OBS benefits only observed in those aged 40 and older.…”

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Table 4_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Data Sheet 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.zip by Xi Luo (361139)

“…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …”

Table 2_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Loss of b-cell K_ATP reduces Ca²⁺ sensitivity of insulin secretion and <i>Trpm5</i> expression by Nathaniel W. York (20410828)

“…Paradoxically, despite the initial insulin hypersecretion, many CHI cases, as well as K_ATP knockout (KO) animals, eventually ‘crossover’ to undersecretion and even diabetes. Here we confirm that S<i>ur1</i> KO islets exhibit higher intracellular [Ca²⁺] (<a href="" target="_blank">[Ca²⁺]_i</a>) at all [glucose], but show decreased glucose-stimulated insulin secretion. …”

Table 3_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Table 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.docx by Xi Luo (361139)

“…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …”

VB2 cell fate analysis of <i>hlh-17</i>, <i>hlh-31</i>, and <i>hlh-32</i> mutant animals. by G. Robert Aguilar (13889674)

“…Error bars indicate standard deviation of the mean. ****<i>p</i> ≤ 0.0001, *<i>p</i> ≤ 0.05, ns: not significant. …”

DataSheet1_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx by Patrick Yawo Kpai (20376234)

“…<p>Cannabis cultivated for medical and adult use is a high-value horticultural crop in North America; however, we lack information on its optimal mineral nutrition due to previous legal restrictions. …”

DataSheet2_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx by Patrick Yawo Kpai (20376234)

“…<p>Cannabis cultivated for medical and adult use is a high-value horticultural crop in North America; however, we lack information on its optimal mineral nutrition due to previous legal restrictions. …”

Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl... by Caroline V. Cameron (22355207)

“…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …”

Bacterium-Phage Symbiosis Facilitates the Enrichment of Bacterial Pathogens and Antibiotic-Resistant Bacteria in the Plastisphere by Rong Xia (30438)

“…The plastisphere phage community exhibited decreased diversity and virulent proportion compared to those found in environments. …”

Relating the biophysical forces that govern bacterial adhesion to experimental data. by Mikkel Anbo (15287803)

“…<p>A: We show that the relative polarity of the expressed serotype correlates with adhesion to tissue culture polystyrene. …”

Pilot study on the impact of HIFU treatment on miRNA profiles in vaginal secretions of uterine fibroids and adenomyosis patients by Wei-Chun Chen (276732)

“…Notably, hsa-miR-7977, hsa-miR-155-5p, hsa-miR-191-5p, and hsa-miR-223-3p showed significant changes in fibroid cases, except in low-energy treatments. hsa-miR-7977 consistently decreased post-treatment, while hsa-miR-155-5p decreased in the least efficient cases. …”

Supplementary file 1_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.docx by Yiwei Yue (22307683)

“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”

Supplementary file 2_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.pdf by Yiwei Yue (22307683)

“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”

Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf by Mattia Dalle Nogare (22696022)

“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Supplementary file 1_Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study.docx by Ee Fung Teo (21181196)

“…There were also significant differences in prokinetic use between institutions.…”