Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…In this study, we utilised structure-based virtual screening (SBVS) from NCI library to discover novel DYRK1A inhibitors. …”

Data Sheet 1_Global, regional, and national disease burden of tobacco-related Alzheimer’s disease among individuals over the age of 55: a global burden of disease study.docx by Tianyi Dong (8060000)

“…It is anticipated that the burden will continue to gradually decrease from 2021 to 2040.</p>Conclusion<p>Although the global burden of tobacco-related Alzheimer’s disease among the older adults declined from 1990 to 2021, significant disparities existed across regions, age groups, sex, and SDI.…”

Data Sheet 1_Synergistic remediation of continuous cropping obstacles in facility agriculture: insights from the Stropharia rugosoannulata-Ornamental Sunflower Rotation System.docx by Jia Lu (181094)

“…The SR-OS2 system significantly enhanced soil properties by increasing pH (+0.57 units), decreasing electrical conductivity (−37.56%), and boosting available phosphorus (+84.2%), while also shifting microbial communities toward bacterial dominance with a 37.4% increase in bacterial Chao1 diversity and a 39.1% decrease in fungal diversity, alongside strengthened bacterial connectivity (+42%) and reduced fungal modularity in co-occurrence networks. …”

Image2_Multi-omics analysis provides insights into the mechanism underlying fruit color formation in Capsicum.tif by Zhao Song (7135202)

“…In this study, the light-yellow color observed in immature CSJ009 fruits compared to CSJ010 could be attributed to decreased chlorophyll and carotenoid pigments. Through integrated analysis of the transcriptome and metabolome of CSJ009 and CSJ010, we identified 23,930 differentially expressed genes (DEGs) and 345 differentially accumulated metabolites (DAMs). …”

Actual Vs predicted revenue. by Guibing You (21728593)

“…To address this challenge, we propose F-TransR, a Transformer-based multimodal revenue prediction model. …”

Supplementary Material for: Streptococcus mutans GcrR regulates oral biofilm from a cariogenic state to a non-cariogenic state by affecting exopolysaccharides production and biofil... by Zhang B. (3112698)

“…The orphan response regulator GcrR negatively regulates exopolysaccharides (EPSs) synthesis in S. mutans. We aimed to investigate the effect of GcrR on the cariogenicity of oral biofilms. …”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Genetic evidence linking gastroesophageal reflux disease to chronic kidney disease and kidney failure: a two-step Mendelian randomization study by Fanghong Zheng (8931326)

“…Interventions with these factors could significantly decrease the burden of CKD attributable to GERD.…”

None - by Sisay Fikadu Jaleta (20912783)

“…<div><p>Malaria remains a significant global health challenge, particularly in developing countries. …”

Image_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.JPEG by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Table_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.DOCX by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Droperidol is associated with reduced length of stay in the treatment of cannabinoid hyperemesis syndrome by Geoffrey S. Kelly (21537766)

“…After adjustments, droperidol use was associated with a reduced length of stay (mean ratio 0.76; 95% CI: 0.62 0.94; <i>P</i> = 0.01), decreased total medication administration (OR 0.34; 95% CI: 0.20–0.58; <i>P <</i>0.001) and decreased usage of opioids (OR 0.16; 95% CI: 0.07–0.39; <i>P <</i>0.001). …”

Image 1_SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.tif by Junchen Pan (19417598)

“…RT-PCR and Western blot analyses were used to investigate the relevant molecular mechanisms.</p>Results<p>We show that SQLE is significantly overexpressed in pancreatic cancer, and abrogation of SQLE results in a significant increase in squalene accumulation within tumor cells. …”

Data Sheet 1_Shifts in soil microbial and nematode communities over progression of pine wilt disease occurring in Pinus koraiensis stands.pdf by Siyu Tian (9874001)

“…Consequently, we observed a lower inter-kingdom network complexity in the soil community of the pines following the PWD, in which the bacterial networks decreased but fungal networks increased in complexity. …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for α-diversity index were estimated using a random effects model. …”

Upper extremity orthopedic softball injuries presenting to the emergency department: epidemiology across the lifespan by David F. Painter (12884672)

“…The average incidence rate of UE injuries from 2012–2021 was 187.9 per 100,000 persons, with a significant decrease in injury incidence across the timespan (<i>p</i> < .001). …”

Data Sheet 1_An in vitro evaluation of intravenous lipid emulsion on three common canine toxicants.docx by Emery Jones (19736377)

“…ILE therapy may have other means of significantly decreasing lipophilic drug concentration in cases of toxicosis.…”

Accuracy rates for deductive (categorical and propositional) and inductive (propositional) arguments before and after left inferior frontal gyrus tDCS. by Shane Fresnoza (8409477)

“…Pairwise comparisons were Bonferroni corrected with a significance level of <i>p</i> ≤ 0.05. Data are presented as mean ± standard error of mean.…”

Accuracy rates for deductive and inductive arguments before and after tDCS of the left dorsolateral prefrontal cortex. by Shane Fresnoza (8409477)

“…Pairwise comparisons were Bonferroni corrected with a significance level of <i>p</i> ≤ 0.05. Data are presented as mean ± standard error of mean.…”

Data Sheet 1_Changes in the community composition and function of the rhizosphere microbiome in tobacco plants with Fusarium root rot.docx by Min Yang (146229)

“…In the root tissues of diseased plants, the Shannon index of bacterial and fungal communities decreased by 17.71–27.05% (P < 0.05). Additionally, we observed that the rhizosphere microbial community of diseased tobacco plants shifted toward a pathological combination, with a significant increase in the relative abundance of harmful microbes such as Alternaria, Fusarium, and Filobasidium (89.46–921.29%) and a notable decrease in the relative abundance of beneficial microbes such as Lysobacter, Streptomyces, Mortierella, and Penicillium (48.48–81.56%). …”