يعرض 4,621 - 4,640 نتائج من 6,221 نتيجة بحث عن 'significantly ((((we decrease) OR (teer decrease))) OR (greatest decrease))', وقت الاستعلام: 0.38s تنقيح النتائج
  1. 4621

    Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury حسب figshare admin karger (2628495)

    منشور في 2025
    "…However, ACOTs' effect on CaOx kidney stone formation remains to be explored. Here, we aimed to investigate the effect of ACOTs on CaOx kidney stone formation. …"
  2. 4622

    Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …"
  3. 4623

    Image 2_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... حسب Khalidah Ibraheem (9525220)

    منشور في 2025
    "…Scalp cooling remains the only available method to mitigate CIA, but its effectiveness varies amongst patients. We previously reported that the cytoprotective effects of cooling are temperature dependent. …"
  4. 4624

    Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …"
  5. 4625

    Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... حسب Junhong Yang (7807046)

    منشور في 2025
    "…</p>Materials and methods<p>We conducted a cross-sectional study on donor hemovigilance data reported to the national network from 2020 to 2022 in China. …"
  6. 4626

    Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... حسب Khalidah Ibraheem (9525220)

    منشور في 2025
    "…Scalp cooling remains the only available method to mitigate CIA, but its effectiveness varies amongst patients. We previously reported that the cytoprotective effects of cooling are temperature dependent. …"
  7. 4627

    Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
  8. 4628

    Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
  9. 4629

    Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
  10. 4630

    Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX حسب Ji Zeng (4336561)

    منشور في 2024
    "…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…"
  11. 4631

    Data_Sheet_1_Banxia-Yiyiren alleviates insomnia and anxiety by regulating the gut microbiota and metabolites of PCPA-induced insomnia model rats.zip حسب Liang Wang (23021)

    منشور في 2024
    "…</p>Materials and methods<p>We employed 16S ribosomal ribonucleic acid (rRNA) gene sequencing combined with metabonomic analysis to explore the mutual effects of the PCPA-induced insomnia model and the gut microbiota and the intrinsic regulatory mechanism of Banxia-Yiyiren on the gut microbiota and metabolites in the PCPA-induced insomnia model.…"
  12. 4632

    Raw data for figures and tables in the paper. حسب Runhai Jiang (19871068)

    منشور في 2024
    "…We employed broth culture and pot experiments to investigate the effect of the inoculation of <i>P</i>. …"
  13. 4633

    Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx حسب Dan-Ni Yang (17642947)

    منشور في 2025
    "…Subgroup analyses with both cohorts revealed the decreased AUC in older patients. The resampling method revealed decreased AUC with the advancement of age.…"
  14. 4634

    Table 4_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf حسب Ziqin Feng (22318243)

    منشور في 2025
    "…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …"
  15. 4635

    Data Sheet 2_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.xlsx حسب Li-Yan Zhang (5091608)

    منشور في 2025
    "…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …"
  16. 4636

    Presentation 1_Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.pptx حسب Ryohei Yamamura (20386047)

    منشور في 2025
    "…Background<p>The advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). …"
  17. 4637

    <b>Litter decomposition regulated by stand ECM dominance but not litter mycorrhizal type in a subtropical mountainous forest</b> حسب Lu Mengzhen (20146224)

    منشور في 2025
    "…</a> AM and ECM litter decomposition in plots with a natural gradient of ECM tree dominance showed that the decomposition rates of both AM litter and ECM litter decreased significantly in plots with increasing ECM dominance. …"
  18. 4638

    Data Sheet 1_Meiotic chiasmata variations in the H genome among Triticeae species of varying ploidy.docx حسب Ying Yang (24175)

    منشور في 2025
    "…The frequency of chiasmata significantly decreased from H. bogdanii to E. sibiricus and H. brevisubulatum in both the terminal and interstitial regions. …"
  19. 4639

    Effect of soil salinity on cotton cultivation and the potential for introducing <i>Amaranthaceae</i> halophytes in the Yellow River Delta, China حسب Hiroshi Takagi (271173)

    منشور في 2025
    "…Levels of major (K<sup>+</sup>, Ca<sup>2+</sup> and Mg<sup>2+</sup>) or minor (Fe<sup>2+</sup>, Mn<sup>2+</sup>, Zn<sup>2+</sup> and Cu<sup>2+</sup>) essential elements were not significantly decreased by the increase of field EC in any plant species, except for K<sup>+</sup> in <i>S</i>. …"
  20. 4640

    Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf حسب Ziqin Feng (22318243)

    منشور في 2025
    "…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …"