Table 1_Working like a mule? The physiological toll of heavy loads on mules.docx by Tamara Tadich (17244898)

“…Enzymatic activities of γ-glutamyltransferase (GGT), lactate dehydrogenase (LDH), and alkaline phosphatase (SAP/ALP) also increased with heavier loads, suggesting greater muscular effort and mild tissue stress. Conversely, glutathione peroxidase (GPx) activity decreased as load increased, implying increased oxidative demand. …”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Table 1_Comparative analysis of soil properties before and after Morchella sextelata cultivation across various soil types.xlsx by Juan Zhao (109151)

“…In this study, our results reveals that cultivation significantly alters soil properties and microbial communities in a soil type-dependent manner. …”

Data Sheet 1_Reducing enteric methane emission in dairy goats: impact of dietary inclusions of quebracho tannin extract on ruminal microbiota.pdf by Paola Cremonesi (5892311)

“…The overall fungal biodiversity was also significantly changed (P < 0.05); the fiber-degrading Liebetanzomyces decreased, while the tannin-degrading Aspergillus increased (P < 0.05). …”

Flowchart of the study. by Ramazan Cevik (19959160)

“…After the intervention, all groups showed increased ROM and decreased VAS and NDI scores (p<0.001). The Mulligan group exhibited significantly greater improvement in VAS, ROM, and NDI compared to other groups (p<0.001). …”

Multi-omics reveals glycolipid metabolism processes during the early development of largemouth bass (Micropterus salmoides) by Yujie Jiang (2991267)

“…Early embryos' yolk and oil droplet diameters decreased significantly with embryonic development (P < 0.05). …”

Data Sheet 1_Increased vegetation disturbance intensity reduces soil nutrients while enhancing microbial network interactions.pdf by Boya Gao (8840498)

“…</p>Results<p>The findings reveal that higher disturbance intensity significantly alters soil nutrient levels, which in turn affects microbial diversity, abundance, community composition, and interspecies interactions. …”

Supplementary file 1_Interspecific association characteristics of Alternanthera philoxeroides-invaded communities and their latitudinal variations.docx by Hao Wu (65943)

“…The ratio of species pairs with positive/negative associations (PNR) in terrestrial communities dramatically decreased at higher latitudes. The values of the Jaccard index (J_A), Ochiai index (O_I), and Dice index (D_I) which represent the interspecific association intensity in terrestrial communities, were extremely significantly greater than those in aquatic communities. …”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…Moreover, cap-dependent protein synthesis was significantly altered by the triple substitution STS/DDD, pointing towards a role of these residues in protein synthesis regulation.…”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …”

Data Sheet 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Frontier analysis showed that as the Socio-demographic Index increased, the disparity in CRC ASRs among countries widened, with developed regions having greater potential to reduce these rates. The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”

Table 3_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.xlsx by Tao Zhang (43681)

“…Frontier analysis showed that as the Socio-demographic Index increased, the disparity in CRC ASRs among countries widened, with developed regions having greater potential to reduce these rates. The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”

Table 2_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Frontier analysis showed that as the Socio-demographic Index increased, the disparity in CRC ASRs among countries widened, with developed regions having greater potential to reduce these rates. The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”

Table 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx by Tao Zhang (43681)

“…Frontier analysis showed that as the Socio-demographic Index increased, the disparity in CRC ASRs among countries widened, with developed regions having greater potential to reduce these rates. The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”

Data Sheet 1_Dietary supplementation with proanthocyanidins and rutin alleviates the symptoms of type 2 diabetes mice and regulates gut microbiota.docx by Yue Gao (263086)

“…Background<p>Obesity and high fasting blood glucose (FBG) resulting from high-fat diets (HFDs) have emerged as significant public health concerns, garnering increasing attention. …”

Table 1_Transcriptomic and metabolomic analysis of carotenoid metabolism and accumulation of carotenoid-derived products in tobacco leaves before and after curing.docx by Tao Liu (10785)

“…Significant decrease in carotenoid contents in leaves was observed during the curing process after harvest. …”

Table 2_Transcriptomic and metabolomic analysis of carotenoid metabolism and accumulation of carotenoid-derived products in tobacco leaves before and after curing.xlsx by Tao Liu (10785)

“…Significant decrease in carotenoid contents in leaves was observed during the curing process after harvest. …”

Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx by Jingtao Wang (828021)

“…At the genus level, the relative abundance of Streptococcus was significantly increased in the dry skin group, whereas a decreasing trend was observed for Cutibacterium. …”

Data Sheet 1_Effect of Bacillus coagulans BC99 supplementation on body weight and gut microbiota in overweight and obese individual: a randomized, double-blind, placebo-controlled... by Rui Wang (52434)

“…Weight loss was significantly greater in the probiotic group than in the placebo group (P < 0.05). …”