Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

DataSheet1_Leaf functional traits highlight phenotypic variation of two tree species in the urban environment.docx by Ahram Cho (20437850)

“…Norway Maple gas exchange values decreased as the growing season progressed, as expected by ontogeny. …”

Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif by Toru Miwa (8528715)

“…MNAM increased SIRT1 protein levels in the cochlea without altering Sirt1 mRNA, suggesting post-transcriptional regulation. …”

Data Sheet 1_Intratumoral microbiota composition in women’s cancers: a systematic review and meta-analysis.docx by Qin Wen (3505655)

“…Compared to adjacent normal tissues, the Simpson index significantly decreased in breast cancer (SMD = -0.75, 95% CI: [-0.94, -0.55]) and endometrial cancer (SMD = -0.83, 95% CI: [-1.37, -0.28]). …”

Table1_Trp-574-Leu and the novel Pro-197-His/Leu mutations contribute to penoxsulam resistance in Echinochloa crus-galli (L.) P. Beauv..docx by Penglei Sun (18343673)

“…Molecular docking studies revealed that Trp-574-Leu mutation primarily reduced the enzyme’s ability to bind to the triazole-pyrimidine ring of penoxsulam due to decreased π–π stacking interactions, while Pro-197-His/Leu mutations impaired binding to the benzene ring by altering hydrogen bonds and hydrophobic interactions. …”

Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx by Asmaa M. El-kady (16502930)

“…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…”

Table 1_Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota.xlsx by Jiangsong Cao (22580375)

“…</p>Results and discussion<p>Compared to the control (CON) group, the gastric ulcer (GU) group exhibited significant pathological alterations in the gastric mucosa. …”

Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

“…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F_V/F_M increased by 39%, Y_II and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”

Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... by Liang Wu (131111)

“…</p>Results<p>HSYA significantly inhibited HFD-induced weight gain and alleviated liver inflammation. …”

DataSheet1_Efferocytosis dysfunction in CXCL4-induced M4 macrophages: phenotypic insights in systemic sclerosis in vitro and in vivo.docx by Erwan Le Tallec (19834785)

“…</p>Results<p>Our results demonstrated that efferocytosis was significantly reduced in M0-MDMs from healthy donors exposed to the CXCL4-rich plasma of SSc patients. …”

Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip by Qiwei Zhao (12519351)

“…Furthermore, CAP increased levels of MDA, Fe²⁺, and ROS while decreasing GSH; these alterations were reversed by Fer-1 treatment. …”

Table 1_A species of Coprococcus is related to BMI in patients who underwent malabsorptive bariatric surgery and its abundance is modified by magnesium and thiamin intake.docx by Fernando Suárez-Sánchez (7552866)

“…The Shannon and Simpson diversity indices decreased significantly after surgery (p < 0.001). …”

Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx by Tangjuan Liu (2634649)

“…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …”

Supplementary file 1_Transcriptome-wide N6-methyladenosinem modifications analysis of chicken cecum in responding to Campylobacter jejuni inoculation.zip by Yanan Zhao (3132906)

“…</p>Results<p>In the S group, the level of proinflammatory cytokines (IL-8, IL-1β, IL-18, TNF-α, IL-17A) and global RNA methylation were significantly decreased (P < 0.05). A total of 30,427 and 30,367 m⁶A peaks were identified in R and S groups, which were primarily located in 3'UTR and CDS regions. …”

The impact of nano-curcumin on cell viability and proliferation in breast cancer cells. by Taraneh Givi (22793530)

“…(C, D) MTT assays were conducted on MCF7-S and MCF7-TR cells following nano-curcumin treatment. Cell viability significantly decreased at all tested time points. (E, F) mRNA Expression levels <i>PI3K</i>, <i>AKT1</i>, <i>mTOR</i>, <i>NF-KB</i>, <i>Cyclin D1</i>, <i>DILA1</i> and <i>PTEN</i> in breast cancer cells. …”

Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study by figshare admin karger (2628495)

“…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …”

Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”

Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg by Johnny Amer (495285)

“…However, the extent to which ALI regulates lung tissue-resident NK (trNK) activity and their molecular phenotypic alterations are not well defined. We aimed to assess the impact of 1,25-hydroxy-vitamin-D3 [1,125(OH)₂D] on ALI clinical outcome in a mouse model and effects on lung trNK cell activations.…”